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Neurocysticercosis
Surjith Vattoth, MD, FRCR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Neurocysticercosis (NCC)
              • Synonyms

                • Cysticercosis
              • Definitions

                • Intracranial parasitic infection caused by pork tapeworm Taenia solium; 4 pathologic stages: 2 vesicular & 2 nodular
                  • Vesicular, colloidal vesicular, granular nodular, & nodular calcified

              IMAGING

              • General Features

                • CT Findings

                  • MR Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Staging, Grading, & Classification

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Arroyo G et al: Albendazole sulfoxide plasma levels and efficacy of antiparasitic treatment in patients with parenchymal neurocysticercosis. Clin Infect Dis. ePub, 2019
                                            2. Ghosh RN et al: Perfusion magnetic resonance imaging in differentiation of neurocysticercosis and tuberculoma. Neuroradiology. 61(3):257-63, 2018
                                            3. Rodrigues A et al: A classic neurocysticercosis case with an unusual complication. Eur J Case Rep Intern Med. 5(1):000762, 2018
                                            4. Del Brutto OH: Neurocysticercosis. Handb Clin Neurol. 121:1445-59, 2014
                                            5. Hernández RD et al: Magnetic resonance imaging in neurocysticercosis. Top Magn Reson Imaging. 23(3):191-8, 2014
                                            6. Bhattacharjee S et al: Clinical profile and follow-up of 51 pediatric neurocysticercosis cases: a study from Eastern India. Ann Indian Acad Neurol. 16(4):549-55, 2013
                                            7. Carpio A et al: Neurocysticercosis: five new things. Neurol Clin Pract. 3(2):118-25, 2013
                                            8. Cuello-García CA et al: Corticosteroids for neurocysticercosis: a systematic review and meta-analysis of randomized controlled trials. Int J Infect Dis. 17(8):e583-92, 2013
                                            9. Souza Ad et al: Solitary cerebral parenchymal cysticercosis: a prospective comparative study with computed tomography and magnetic resonance imaging. Neurol India. 61(6):639-43, 2013
                                            10. Lerner A et al: Imaging of neurocysticercosis. Neuroimaging Clin N Am. 22(4):659-76, 2012
                                            11. Sinha S et al: Intraventricular neurocysticercosis: a review of current status and management issues. Br J Neurosurg. 26(3):305-9, 2012
                                            12. Matushita H et al: Hydrocephalus in neurocysticercosis. Childs Nerv Syst. 27(10):1709-21, 2011
                                            13. Angeles CF et al: Transventricular neuroendoscopic excision of giant racemose subarachnoid cysticercosis. Childs Nerv Syst. 25(4):503-8, 2009
                                            14. Sinha S et al: Neurocysticercosis: a review of current status and management. J Clin Neurosci. 16(7):867-76, 2009
                                            15. Goel RK et al: Endoscopic management of intraventricular neurocysticercosis. J Clin Neurosci. 15(10):1096-101, 2008
                                            16. Handique SK et al: Coinfection of Japanese encephalitis with neurocysticercosis: an imaging study. AJNR Am J Neuroradiol. 29(1):170-5, 2008
                                            17. Jimenez-Vazquez OH et al: Cisternal neurocysticercosis. Br J Neurosurg. 22(6):774-5, 2008
                                            18. Jung H et al: Medical treatment for neurocysticercosis: drugs, indications and perspectives. Curr Top Med Chem. 8(5):424-33, 2008
                                            19. Kraft R: Cysticercosis: an emerging parasitic disease. Am Fam Physician. 2007 Jul 1;76(1):91-6. Review. Erratum in: Am Fam Physician. 77(6):748, 2008
                                            20. Odermatt P et al: Treatment of neurocysticercosis: a randomised controlled trial. J Neurol Neurosurg Psychiatry. 79(9):978, 2008
                                            21. Kwee RM et al: Virchow-Robin spaces at MR imaging. Radiographics. 27(4):1071-86, 2007
                                            22. Lucato LT et al: The role of conventional MR imaging sequences in the evaluation of neurocysticercosis: impact on characterization of the scolex and lesion burden. AJNR Am J Neuroradiol. 28(8):1501-4, 2007
                                            23. Mathews M et al: Intraventricular cryptococcal cysts masquerading as racemose neurocysticercosis. Surg Neurol. 67(6):647-9, 2007
                                            24. Bhigjee AI et al: Optimizing therapy of seizures in patients with HIV and cysticercosis. Neurology. 67(12 Suppl 4):S19-22, 2006
                                            25. Reddy JS et al: The role of diffusion-weighted imaging in the differential diagnosis of intracranial cystic mass lesions: a report of 147 lesions. Surg Neurol. 66(3):246-50; discussion 250-1, 2006
                                            26. Sáenz B et al: Neurocysticercosis: clinical, radiologic, and inflammatory differences between children and adults. Pediatr Infect Dis J. 25(9):801-3, 2006
                                            27. Velasco TR et al: Calcified cysticercotic lesions and intractable epilepsy: a cross sectional study of 512 patients. J Neurol Neurosurg Psychiatry. 77(4):485-8, 2006
                                            28. Jayakumar PN et al: MRI and in vivo proton MR spectroscopy in a racemose cysticercal cyst of the brain. Neuroradiology. 46(1):72-4, 2004
                                            29. Garcia HH et al: Taenia solium cysticercosis. Lancet. 362(9383):547-56, 2003
                                            30. Zee CS et al: Imaging of neurocysticercosis. Neuroimaging Clin N Am. 10(2):391-407, 2000
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Pathology

                                                    • Clinical Issues

                                                      • Diagnostic Checklist

                                                        TERMINOLOGY

                                                        • Abbreviations

                                                          • Neurocysticercosis (NCC)
                                                        • Synonyms

                                                          • Cysticercosis
                                                        • Definitions

                                                          • Intracranial parasitic infection caused by pork tapeworm Taenia solium; 4 pathologic stages: 2 vesicular & 2 nodular
                                                            • Vesicular, colloidal vesicular, granular nodular, & nodular calcified

                                                        IMAGING

                                                        • General Features

                                                          • CT Findings

                                                            • MR Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Staging, Grading, & Classification

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  DIAGNOSTIC CHECKLIST

                                                                                  • Consider

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Arroyo G et al: Albendazole sulfoxide plasma levels and efficacy of antiparasitic treatment in patients with parenchymal neurocysticercosis. Clin Infect Dis. ePub, 2019
                                                                                      2. Ghosh RN et al: Perfusion magnetic resonance imaging in differentiation of neurocysticercosis and tuberculoma. Neuroradiology. 61(3):257-63, 2018
                                                                                      3. Rodrigues A et al: A classic neurocysticercosis case with an unusual complication. Eur J Case Rep Intern Med. 5(1):000762, 2018
                                                                                      4. Del Brutto OH: Neurocysticercosis. Handb Clin Neurol. 121:1445-59, 2014
                                                                                      5. Hernández RD et al: Magnetic resonance imaging in neurocysticercosis. Top Magn Reson Imaging. 23(3):191-8, 2014
                                                                                      6. Bhattacharjee S et al: Clinical profile and follow-up of 51 pediatric neurocysticercosis cases: a study from Eastern India. Ann Indian Acad Neurol. 16(4):549-55, 2013
                                                                                      7. Carpio A et al: Neurocysticercosis: five new things. Neurol Clin Pract. 3(2):118-25, 2013
                                                                                      8. Cuello-García CA et al: Corticosteroids for neurocysticercosis: a systematic review and meta-analysis of randomized controlled trials. Int J Infect Dis. 17(8):e583-92, 2013
                                                                                      9. Souza Ad et al: Solitary cerebral parenchymal cysticercosis: a prospective comparative study with computed tomography and magnetic resonance imaging. Neurol India. 61(6):639-43, 2013
                                                                                      10. Lerner A et al: Imaging of neurocysticercosis. Neuroimaging Clin N Am. 22(4):659-76, 2012
                                                                                      11. Sinha S et al: Intraventricular neurocysticercosis: a review of current status and management issues. Br J Neurosurg. 26(3):305-9, 2012
                                                                                      12. Matushita H et al: Hydrocephalus in neurocysticercosis. Childs Nerv Syst. 27(10):1709-21, 2011
                                                                                      13. Angeles CF et al: Transventricular neuroendoscopic excision of giant racemose subarachnoid cysticercosis. Childs Nerv Syst. 25(4):503-8, 2009
                                                                                      14. Sinha S et al: Neurocysticercosis: a review of current status and management. J Clin Neurosci. 16(7):867-76, 2009
                                                                                      15. Goel RK et al: Endoscopic management of intraventricular neurocysticercosis. J Clin Neurosci. 15(10):1096-101, 2008
                                                                                      16. Handique SK et al: Coinfection of Japanese encephalitis with neurocysticercosis: an imaging study. AJNR Am J Neuroradiol. 29(1):170-5, 2008
                                                                                      17. Jimenez-Vazquez OH et al: Cisternal neurocysticercosis. Br J Neurosurg. 22(6):774-5, 2008
                                                                                      18. Jung H et al: Medical treatment for neurocysticercosis: drugs, indications and perspectives. Curr Top Med Chem. 8(5):424-33, 2008
                                                                                      19. Kraft R: Cysticercosis: an emerging parasitic disease. Am Fam Physician. 2007 Jul 1;76(1):91-6. Review. Erratum in: Am Fam Physician. 77(6):748, 2008
                                                                                      20. Odermatt P et al: Treatment of neurocysticercosis: a randomised controlled trial. J Neurol Neurosurg Psychiatry. 79(9):978, 2008
                                                                                      21. Kwee RM et al: Virchow-Robin spaces at MR imaging. Radiographics. 27(4):1071-86, 2007
                                                                                      22. Lucato LT et al: The role of conventional MR imaging sequences in the evaluation of neurocysticercosis: impact on characterization of the scolex and lesion burden. AJNR Am J Neuroradiol. 28(8):1501-4, 2007
                                                                                      23. Mathews M et al: Intraventricular cryptococcal cysts masquerading as racemose neurocysticercosis. Surg Neurol. 67(6):647-9, 2007
                                                                                      24. Bhigjee AI et al: Optimizing therapy of seizures in patients with HIV and cysticercosis. Neurology. 67(12 Suppl 4):S19-22, 2006
                                                                                      25. Reddy JS et al: The role of diffusion-weighted imaging in the differential diagnosis of intracranial cystic mass lesions: a report of 147 lesions. Surg Neurol. 66(3):246-50; discussion 250-1, 2006
                                                                                      26. Sáenz B et al: Neurocysticercosis: clinical, radiologic, and inflammatory differences between children and adults. Pediatr Infect Dis J. 25(9):801-3, 2006
                                                                                      27. Velasco TR et al: Calcified cysticercotic lesions and intractable epilepsy: a cross sectional study of 512 patients. J Neurol Neurosurg Psychiatry. 77(4):485-8, 2006
                                                                                      28. Jayakumar PN et al: MRI and in vivo proton MR spectroscopy in a racemose cysticercal cyst of the brain. Neuroradiology. 46(1):72-4, 2004
                                                                                      29. Garcia HH et al: Taenia solium cysticercosis. Lancet. 362(9383):547-56, 2003
                                                                                      30. Zee CS et al: Imaging of neurocysticercosis. Neuroimaging Clin N Am. 10(2):391-407, 2000