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Neurogenic Neoplasms of the Nerve Sheath
Sherief H. Garrana, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Definitions

              • Peripheral nerve sheath tumor (PNST)
                • Schwannoma
                • Neurofibroma
              • Malignant peripheral nerve sheath tumor (MPNST)
                • Spindle cell sarcoma of nerve sheath origin

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Dewey BJ et al: FDG PET/CT and MRI features of pathologically proven schwannomas. Clin Nucl Med. 46(4):289-96, 2021
                                          2. Wilson MP et al: Diagnostic accuracy of MRI for the detection of malignant peripheral nerve sheath tumors: a systematic review and meta-analysis. AJR Am J Roentgenol. 1-9, 2021
                                          3. Pavlus JD et al: Imaging of thoracic neurogenic tumors. AJR Am J Roentgenol. 1-10, 2016
                                          4. Abreu E et al: Peripheral tumor and tumor-like neurogenic lesions. Eur J Radiol. 82(1):38-50, 2011
                                          5. Nam SJ et al: Imaging of primary chest wall tumors with radiologic-pathologic correlation. Radiographics. 31(3):749-70, 2011
                                          6. Kang J et al: Manifestations of systemic diseases on thoracic imaging. Curr Probl Diagn Radiol. 39(6):247-61, 2010
                                          7. Woertler K: Tumors and tumor-like lesions of peripheral nerves. Semin Musculoskelet Radiol. 14(5):547-58, 2010
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Definitions

                                                      • Peripheral nerve sheath tumor (PNST)
                                                        • Schwannoma
                                                        • Neurofibroma
                                                      • Malignant peripheral nerve sheath tumor (MPNST)
                                                        • Spindle cell sarcoma of nerve sheath origin

                                                    IMAGING

                                                    • General Features

                                                      • Radiographic Findings

                                                        • CT Findings

                                                          • MR Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Dewey BJ et al: FDG PET/CT and MRI features of pathologically proven schwannomas. Clin Nucl Med. 46(4):289-96, 2021
                                                                                  2. Wilson MP et al: Diagnostic accuracy of MRI for the detection of malignant peripheral nerve sheath tumors: a systematic review and meta-analysis. AJR Am J Roentgenol. 1-9, 2021
                                                                                  3. Pavlus JD et al: Imaging of thoracic neurogenic tumors. AJR Am J Roentgenol. 1-10, 2016
                                                                                  4. Abreu E et al: Peripheral tumor and tumor-like neurogenic lesions. Eur J Radiol. 82(1):38-50, 2011
                                                                                  5. Nam SJ et al: Imaging of primary chest wall tumors with radiologic-pathologic correlation. Radiographics. 31(3):749-70, 2011
                                                                                  6. Kang J et al: Manifestations of systemic diseases on thoracic imaging. Curr Probl Diagn Radiol. 39(6):247-61, 2010
                                                                                  7. Woertler K: Tumors and tumor-like lesions of peripheral nerves. Semin Musculoskelet Radiol. 14(5):547-58, 2010