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Neurogenic Neoplasms of the Sympathetic Ganglia
John P. Lichtenberger, III, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Definitions

              • Ganglioneuroma: Benign neoplasm of sympathetic ganglia
              • Ganglioneuroblastoma, neuroblastoma: Malignant neoplasms of sympathetic ganglia
              • Paraganglioma: Neoplasm of paraganglion cells in sympathetic or parasympathetic chains

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            Selected References

                                            1. Carter BW et al: Imaging of the posterior/paravertebral mediastinum. Radiol Clin North Am. 59(2):243-9, 2021
                                            2. Park JW et al: Pictorial review of mediastinal masses with an emphasis on magnetic resonance imaging. Korean J Radiol. 22(1):139-54, 2021
                                            3. Pavlus JD et al: Imaging of thoracic neurogenic tumors. AJR Am J Roentgenol. 1-10, 2016
                                            4. Woo OH et al: Wide spectrum of thoracic neurogenic tumours: a pictorial review of CT and pathological findings. Br J Radiol. 81(968):668-76, 2008
                                            5. Ilias I et al: New functional imaging modalities for chromaffin tumors, neuroblastomas and ganglioneuromas. Trends Endocrinol Metab. 16(2):66-72, 2005
                                            6. Sahdev A et al: CT and MR imaging of unusual locations of extra-adrenal paragangliomas (pheochromocytomas). Eur Radiol. 15(1):85-92, 2005
                                            7. Tanaka O et al: Neurogenic tumors of the mediastinum and chest wall: MR imaging appearance. J Thorac Imaging. 20(4):316-20, 2005
                                            8. Lonergan GJ et al: Neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: radiologic-pathologic correlation. Radiographics. 22(4):911-34, 2002
                                            9. Aquino SL et al: Nerves of the thorax: atlas of normal and pathologic findings. Radiographics. 21(5):1275-81, 2001
                                            10. Erasmus JJ et al: MR imaging of mediastinal masses. Magn Reson Imaging Clin N Am. 8(1):59-89, 2000
                                            11. Reeder LB: Neurogenic tumors of the mediastinum. Semin Thorac Cardiovasc Surg. 12(4):261-7, 2000
                                            12. Lee JY et al: Spectrum of neurogenic tumors in the thorax: CT and pathologic findings. J Comput Assist Tomogr. 23(3):399-406, 1999
                                            13. Strollo DC et al: Primary mediastinal tumors: part II. Tumors of the middle and posterior mediastinum. Chest. 112(5):1344-57, 1997
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Definitions

                                                        • Ganglioneuroma: Benign neoplasm of sympathetic ganglia
                                                        • Ganglioneuroblastoma, neuroblastoma: Malignant neoplasms of sympathetic ganglia
                                                        • Paraganglioma: Neoplasm of paraganglion cells in sympathetic or parasympathetic chains

                                                      IMAGING

                                                      • General Features

                                                        • Radiographic Findings

                                                          • CT Findings

                                                            • MR Findings

                                                              • Nuclear Medicine Findings

                                                                • Imaging Recommendations

                                                                  DIFFERENTIAL DIAGNOSIS

                                                                    PATHOLOGY

                                                                    • General Features

                                                                      • Staging, Grading, & Classification

                                                                        • Gross Pathologic & Surgical Features

                                                                          • Microscopic Features

                                                                            CLINICAL ISSUES

                                                                            • Presentation

                                                                              • Demographics

                                                                                • Natural History & Prognosis

                                                                                  • Treatment

                                                                                    DIAGNOSTIC CHECKLIST

                                                                                    • Consider

                                                                                      Selected References

                                                                                      1. Carter BW et al: Imaging of the posterior/paravertebral mediastinum. Radiol Clin North Am. 59(2):243-9, 2021
                                                                                      2. Park JW et al: Pictorial review of mediastinal masses with an emphasis on magnetic resonance imaging. Korean J Radiol. 22(1):139-54, 2021
                                                                                      3. Pavlus JD et al: Imaging of thoracic neurogenic tumors. AJR Am J Roentgenol. 1-10, 2016
                                                                                      4. Woo OH et al: Wide spectrum of thoracic neurogenic tumours: a pictorial review of CT and pathological findings. Br J Radiol. 81(968):668-76, 2008
                                                                                      5. Ilias I et al: New functional imaging modalities for chromaffin tumors, neuroblastomas and ganglioneuromas. Trends Endocrinol Metab. 16(2):66-72, 2005
                                                                                      6. Sahdev A et al: CT and MR imaging of unusual locations of extra-adrenal paragangliomas (pheochromocytomas). Eur Radiol. 15(1):85-92, 2005
                                                                                      7. Tanaka O et al: Neurogenic tumors of the mediastinum and chest wall: MR imaging appearance. J Thorac Imaging. 20(4):316-20, 2005
                                                                                      8. Lonergan GJ et al: Neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: radiologic-pathologic correlation. Radiographics. 22(4):911-34, 2002
                                                                                      9. Aquino SL et al: Nerves of the thorax: atlas of normal and pathologic findings. Radiographics. 21(5):1275-81, 2001
                                                                                      10. Erasmus JJ et al: MR imaging of mediastinal masses. Magn Reson Imaging Clin N Am. 8(1):59-89, 2000
                                                                                      11. Reeder LB: Neurogenic tumors of the mediastinum. Semin Thorac Cardiovasc Surg. 12(4):261-7, 2000
                                                                                      12. Lee JY et al: Spectrum of neurogenic tumors in the thorax: CT and pathologic findings. J Comput Assist Tomogr. 23(3):399-406, 1999
                                                                                      13. Strollo DC et al: Primary mediastinal tumors: part II. Tumors of the middle and posterior mediastinum. Chest. 112(5):1344-57, 1997