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Neurosarcoid
Anne G. Osborn, MD, FACR; Gregory L. Katzman, MD, MBA
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Neurosarcoid (NS)
              • Definitions

                • Chronic multisystem inflammatory disease characterized by noncaseating epithelioid-cell granulomas

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Nuclear Medicine Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              Selected References

                                              1. Carlson ML et al: Cranial base manifestations of neurosarcoidosis: a review of 305 patients. Otol Neurotol. 36(1):156-66, 2015
                                              2. Hebel R et al: Overview of neurosarcoidosis: recent advances. J Neurol. 262(2):258-67, 2015
                                              3. Mercan M et al: A case of sarcoidosis of the central nervous system and orbita. Case Rep Med. 2015:403459, 2015
                                              4. Wegener S et al: Clinically isolated neurosarcoidosis: a recommended diagnostic path. Eur Neurol. 73(1-2):71-7, 2015
                                              5. Wiśniewski K et al: Isolated neurosarcoidosis mimicking intracranial tumours - Analysis of 3 cases. Neurocirugia (Astur). ePub, 2015
                                              6. Demir MK et al: Rare and challenging extra-axial brain lesions: CT and MRI findings with clinico-radiological differential diagnosis and pathological correlation. Diagn Interv Radiol. 20(5):448-52, 2014
                                              7. Shah R et al: Correlation of MR imaging findings and clinical manifestations in neurosarcoidosis. AJNR Am J Neuroradiol. 30(5):953-61, 2009
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Pathology

                                                      • Clinical Issues

                                                        • Diagnostic Checklist

                                                          TERMINOLOGY

                                                          • Abbreviations

                                                            • Neurosarcoid (NS)
                                                          • Definitions

                                                            • Chronic multisystem inflammatory disease characterized by noncaseating epithelioid-cell granulomas

                                                          IMAGING

                                                          • General Features

                                                            • Radiographic Findings

                                                              • CT Findings

                                                                • MR Findings

                                                                  • Nuclear Medicine Findings

                                                                    • Imaging Recommendations

                                                                      DIFFERENTIAL DIAGNOSIS

                                                                        PATHOLOGY

                                                                        • General Features

                                                                          • Gross Pathologic & Surgical Features

                                                                            • Microscopic Features

                                                                              CLINICAL ISSUES

                                                                              • Presentation

                                                                                • Demographics

                                                                                  • Natural History & Prognosis

                                                                                    • Treatment

                                                                                      DIAGNOSTIC CHECKLIST

                                                                                      • Consider

                                                                                        • Image Interpretation Pearls

                                                                                          Selected References

                                                                                          1. Carlson ML et al: Cranial base manifestations of neurosarcoidosis: a review of 305 patients. Otol Neurotol. 36(1):156-66, 2015
                                                                                          2. Hebel R et al: Overview of neurosarcoidosis: recent advances. J Neurol. 262(2):258-67, 2015
                                                                                          3. Mercan M et al: A case of sarcoidosis of the central nervous system and orbita. Case Rep Med. 2015:403459, 2015
                                                                                          4. Wegener S et al: Clinically isolated neurosarcoidosis: a recommended diagnostic path. Eur Neurol. 73(1-2):71-7, 2015
                                                                                          5. Wiśniewski K et al: Isolated neurosarcoidosis mimicking intracranial tumours - Analysis of 3 cases. Neurocirugia (Astur). ePub, 2015
                                                                                          6. Demir MK et al: Rare and challenging extra-axial brain lesions: CT and MRI findings with clinico-radiological differential diagnosis and pathological correlation. Diagn Interv Radiol. 20(5):448-52, 2014
                                                                                          7. Shah R et al: Correlation of MR imaging findings and clinical manifestations in neurosarcoidosis. AJNR Am J Neuroradiol. 30(5):953-61, 2009