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Non-Small Cell Lung Cancer
Anita Thomas, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        TERMINOLOGY

        • Definitions

          • Non-small cell lung cancer (NSCLC)
            • Group of lung cancers arising from secretory cells
            • Accounts for 85% of all lung cancers
            • Squamous cell carcinoma, large cell carcinoma, adenocarcinoma, and adenocarcinoma in situ

        IMAGING

        • F-18 FDG PET/CT Findings

          DIFFERENTIAL DIAGNOSIS

            PATHOLOGY

            • General Features

              • Staging, Grading, & Classification

                • Microscopic Features

                  CLINICAL ISSUES

                  • Presentation

                    • Demographics

                      • Natural History & Prognosis

                        • Treatment

                          • Surgery

                            • Combined Chemoradiation

                              • Systemic Therapy

                                • Radiation Therapy

                                  DIAGNOSTIC CHECKLIST

                                  • Image Interpretation Pearls

                                    Selected References

                                    1. Mena E et al: The current and evolving role of PET in personalized management of lung lancer. PET Clin. 11(3):243-59, 2016
                                    2. Grootjans W et al: PET in the management of locally advanced and metastatic NSCLC. Nat Rev Clin Oncol. 12(7):395-407, 2015
                                    3. Vilstrup MH et al: [18F]fluorodeoxyglucose PET in thoracic malignancies.PET Clin. 9(4):391-420, v, 2014
                                    4. Detterbeck FC et al: Screening for lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 143(5 Suppl):e78S-92S, 2013
                                    5. Gregory DL et al: Effect of PET/CT on management of patients with non-small cell lung cancer: results of a prospective study with 5-year survival data. J Nucl Med. 53(7):1007-15, 2012
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Top Differential Diagnoses

                                          TERMINOLOGY

                                          • Definitions

                                            • Non-small cell lung cancer (NSCLC)
                                              • Group of lung cancers arising from secretory cells
                                              • Accounts for 85% of all lung cancers
                                              • Squamous cell carcinoma, large cell carcinoma, adenocarcinoma, and adenocarcinoma in situ

                                          IMAGING

                                          • F-18 FDG PET/CT Findings

                                            DIFFERENTIAL DIAGNOSIS

                                              PATHOLOGY

                                              • General Features

                                                • Staging, Grading, & Classification

                                                  • Microscopic Features

                                                    CLINICAL ISSUES

                                                    • Presentation

                                                      • Demographics

                                                        • Natural History & Prognosis

                                                          • Treatment

                                                            • Surgery

                                                              • Combined Chemoradiation

                                                                • Systemic Therapy

                                                                  • Radiation Therapy

                                                                    DIAGNOSTIC CHECKLIST

                                                                    • Image Interpretation Pearls

                                                                      Selected References

                                                                      1. Mena E et al: The current and evolving role of PET in personalized management of lung lancer. PET Clin. 11(3):243-59, 2016
                                                                      2. Grootjans W et al: PET in the management of locally advanced and metastatic NSCLC. Nat Rev Clin Oncol. 12(7):395-407, 2015
                                                                      3. Vilstrup MH et al: [18F]fluorodeoxyglucose PET in thoracic malignancies.PET Clin. 9(4):391-420, v, 2014
                                                                      4. Detterbeck FC et al: Screening for lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 143(5 Suppl):e78S-92S, 2013
                                                                      5. Gregory DL et al: Effect of PET/CT on management of patients with non-small cell lung cancer: results of a prospective study with 5-year survival data. J Nucl Med. 53(7):1007-15, 2012