Benign and generally self-limiting spindle cell tumor of bone containing osteoclast-like giant cells
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Reporting Tips
Selected References
Baumhoer D et al: Non-ossifying fibroma. In Fletcher CDM et al: WHO Classification of Tumours: Tumours of Soft Tissue and Bone. IARC Press. 447-8, 2020
Goldin AN et al: Nonossifying fibromas: a computed tomography-based criteria to predict fracture risk. J Pediatr Orthop. 40(2):e149-54, 2020
Sakamoto A et al: Non-ossifying fibromas: case series, including in uncommon upper extremity sites. World J Orthop. 8(7):561-6, 2017
Wadhwa V et al: Enlarging nonossifying fibroma mimicking aggressive bone tumour. Indian J Cancer. 50(4):301, 2013
Sakamoto A et al: Nonossifying fibroma accompanied by pathological fracture in a 12-year-old runner. J Orthop Sports Phys Ther. 38(7):434-8, 2008
Hetts SW et al: Case 110: Nonossifying fibroma. Radiology. 243(1):288-92, 2007
von Falck C et al: Nonossifying fibroma can mimic residual lymphoma in FDG PET: additional value of combined PET/CT. Clin Nucl Med. 32(8):640-2, 2007
Goodin GS et al: PET/CT characterization of fibroosseous defects in children: 18F-FDG uptake can mimic metastatic disease. AJR Am J Roentgenol. 2006 Oct;187(4):1124-8. Erratum in: AJR Am J Roentgenol. 187(5):1146, 2006
Drubach LA et al: Stress-induced fracture involving a nonossifying fibroma. Clin Nucl Med. 29(1):41-2, 2004
Levine SM et al: Cortical lesions of the tibia: characteristic appearances at conventional radiography. Radiographics. 23(1):157-77, 2003
Nelson M et al: Translocation (1;4)(p31;q34) in nonossifying fibroma. Cancer Genet Cytogenet. 142(2):142-4, 2003
Smith SE et al: Primary musculoskeletal tumors of fibrous origin. Semin Musculoskelet Radiol. 4(1):73-88, 2000
Greenspan A et al: Differential Diagnosis of Tumors and Tumor-like Lesions of Bones and Joints. Lippincott-Raven. 205-9, 1998
Jee WH et al: Nonossifying fibroma: characteristics at MR imaging with pathologic correlation. Radiology. 209(1):197-202, 1998
Benign and generally self-limiting spindle cell tumor of bone containing osteoclast-like giant cells
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Reporting Tips
Selected References
Baumhoer D et al: Non-ossifying fibroma. In Fletcher CDM et al: WHO Classification of Tumours: Tumours of Soft Tissue and Bone. IARC Press. 447-8, 2020
Goldin AN et al: Nonossifying fibromas: a computed tomography-based criteria to predict fracture risk. J Pediatr Orthop. 40(2):e149-54, 2020
Sakamoto A et al: Non-ossifying fibromas: case series, including in uncommon upper extremity sites. World J Orthop. 8(7):561-6, 2017
Wadhwa V et al: Enlarging nonossifying fibroma mimicking aggressive bone tumour. Indian J Cancer. 50(4):301, 2013
Sakamoto A et al: Nonossifying fibroma accompanied by pathological fracture in a 12-year-old runner. J Orthop Sports Phys Ther. 38(7):434-8, 2008
Hetts SW et al: Case 110: Nonossifying fibroma. Radiology. 243(1):288-92, 2007
von Falck C et al: Nonossifying fibroma can mimic residual lymphoma in FDG PET: additional value of combined PET/CT. Clin Nucl Med. 32(8):640-2, 2007
Goodin GS et al: PET/CT characterization of fibroosseous defects in children: 18F-FDG uptake can mimic metastatic disease. AJR Am J Roentgenol. 2006 Oct;187(4):1124-8. Erratum in: AJR Am J Roentgenol. 187(5):1146, 2006
Drubach LA et al: Stress-induced fracture involving a nonossifying fibroma. Clin Nucl Med. 29(1):41-2, 2004
Levine SM et al: Cortical lesions of the tibia: characteristic appearances at conventional radiography. Radiographics. 23(1):157-77, 2003
Nelson M et al: Translocation (1;4)(p31;q34) in nonossifying fibroma. Cancer Genet Cytogenet. 142(2):142-4, 2003
Smith SE et al: Primary musculoskeletal tumors of fibrous origin. Semin Musculoskelet Radiol. 4(1):73-88, 2000
Greenspan A et al: Differential Diagnosis of Tumors and Tumor-like Lesions of Bones and Joints. Lippincott-Raven. 205-9, 1998
Jee WH et al: Nonossifying fibroma: characteristics at MR imaging with pathologic correlation. Radiology. 209(1):197-202, 1998
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