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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Malignant germ cell neoplasm (MGCN)
Definitions
- Primary mediastinal MGCN
- Yolk sac (endodermal sinus) tumor
- Choriocarcinoma
- Embryonal carcinoma
- Mixed type germ cell neoplasm
- Primary mediastinal MGCN
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
PET/CT
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Gillian TD, Kantoff PW: Extragonadal germ cell tumors involving the mediastinum and retroperitoneum. Uptodate.com. accessed 7/14/2011
- Fedyanin M et al: Prognostic factors and efficacy of different chemotherapeutic regimens in patients with mediastinal nonseminomatous germ cell tumors. J Cancer Res Clin Oncol. 140(2):311-8, 2014
- Fukui N et al: Treatment outcome of patients with extragonadal nonseminomatous germ cell tumors: the Saitama Cancer Center experience. Int J Clin Oncol. 18(4):731-4, 2013
- Ueno T et al: Spectrum of germ cell tumors: from head to toe. Radiographics. 24(2):387-404, 2004
- Rosado-de-Christenson ML et al: From the archives of the AFIP. Mediastinal germ cell tumors: radiologic and pathologic correlation. Radiographics. 12(5):1013-30, 1992
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Malignant germ cell neoplasm (MGCN)
Definitions
- Primary mediastinal MGCN
- Yolk sac (endodermal sinus) tumor
- Choriocarcinoma
- Embryonal carcinoma
- Mixed type germ cell neoplasm
- Primary mediastinal MGCN
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
PET/CT
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Gillian TD, Kantoff PW: Extragonadal germ cell tumors involving the mediastinum and retroperitoneum. Uptodate.com. accessed 7/14/2011
- Fedyanin M et al: Prognostic factors and efficacy of different chemotherapeutic regimens in patients with mediastinal nonseminomatous germ cell tumors. J Cancer Res Clin Oncol. 140(2):311-8, 2014
- Fukui N et al: Treatment outcome of patients with extragonadal nonseminomatous germ cell tumors: the Saitama Cancer Center experience. Int J Clin Oncol. 18(4):731-4, 2013
- Ueno T et al: Spectrum of germ cell tumors: from head to toe. Radiographics. 24(2):387-404, 2004
- Rosado-de-Christenson ML et al: From the archives of the AFIP. Mediastinal germ cell tumors: radiologic and pathologic correlation. Radiographics. 12(5):1013-30, 1992
