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Normal Prepubertal Uterus and Ovaries
Sara M. O'Hara, MD, FAAP
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        TERMINOLOGY

        • Definitions

          • Varied appearance of uterus & ovaries with age
            • Prominence in newborns due to maternal hormones
            • Small, quiescent stage in ages 1-8 years
            • Growth with hormonal surge during puberty
          • Thelarche: Onset & progress of breast development
          • Adrenarche: Onset & progress of pubic & axillary hair development
          • Menarche: 1st episode of vaginal bleeding

        IMAGING

        • General Features

          • Ultrasonographic Findings

            • MR Findings

              • CT Findings

                • Imaging Recommendations

                  DIFFERENTIAL DIAGNOSIS

                    Selected References

                    1. Bhagwat NM et al: Asymmetrical ovarian enlargement: caught timely before the cut! J Pediatr Adolesc Gynecol. 28(3):e83-5, 2015
                    2. Bumbuliene Z et al: Uterine size and ovarian size in adolescents with functional hypothalamic amenorrhoea. Arch Dis Child. 100(10):948-51, 2015
                    3. Asăvoaie C et al: Ovarian and uterine ultrasonography in pediatric patients. Pictorial essay. Med Ultrason. 16(2):160-7, 2014
                    4. Heo SH et al: Review of ovarian tumors in children and adolescents: radiologic-pathologic correlation. Radiographics. 34(7):2039-55, 2014
                    5. Nayak S et al: Vaginal foreign body: a delayed diagnosis. J Pediatr Adolesc Gynecol. 27(6):e127-9, 2014
                    6. Tinggaard J et al: Ovarian morphology and function during growth hormone therapy of short girls born small for gestational age. Fertil Steril. 102(6):1733-41, 2014
                    7. Eksioglu AS et al: Value of pelvic sonography in the diagnosis of various forms of precocious puberty in girls. J Clin Ultrasound. 41(2):84-93, 2013
                    8. Pienkowski C et al: Ovarian cysts in prepubertal girls. Endocr Dev. 22:101-11, 2012
                    9. Cleemann L et al: Uterus and ovaries in girls and young women with Turner syndrome evaluated by ultrasound and magnetic resonance imaging. Clin Endocrinol (Oxf). 74(6):756-61, 2011
                    10. Razzaghy-Azar M et al: Sonographic measurement of uterus and ovaries in premenarcheal healthy girls between 6 and 13 years old: correlation with age and pubertal status. J Clin Ultrasound. 39(2):64-73, 2011
                    11. Sathasivam A et al: Pelvic ultrasonography in the evaluation of central precocious puberty: comparison with leuprolide stimulation test. J Pediatr. 159(3):490-5, 2011
                    12. Garel L et al: US of the pediatric female pelvis: a clinical perspective. Radiographics. 21(6):1393-407, 2001
                    Related Anatomy
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                    Related Differential Diagnoses
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                    References
                    Tables

                    Tables

                    KEY FACTS

                    • Terminology

                      • Imaging

                        • Top Differential Diagnoses

                          TERMINOLOGY

                          • Definitions

                            • Varied appearance of uterus & ovaries with age
                              • Prominence in newborns due to maternal hormones
                              • Small, quiescent stage in ages 1-8 years
                              • Growth with hormonal surge during puberty
                            • Thelarche: Onset & progress of breast development
                            • Adrenarche: Onset & progress of pubic & axillary hair development
                            • Menarche: 1st episode of vaginal bleeding

                          IMAGING

                          • General Features

                            • Ultrasonographic Findings

                              • MR Findings

                                • CT Findings

                                  • Imaging Recommendations

                                    DIFFERENTIAL DIAGNOSIS

                                      Selected References

                                      1. Bhagwat NM et al: Asymmetrical ovarian enlargement: caught timely before the cut! J Pediatr Adolesc Gynecol. 28(3):e83-5, 2015
                                      2. Bumbuliene Z et al: Uterine size and ovarian size in adolescents with functional hypothalamic amenorrhoea. Arch Dis Child. 100(10):948-51, 2015
                                      3. Asăvoaie C et al: Ovarian and uterine ultrasonography in pediatric patients. Pictorial essay. Med Ultrason. 16(2):160-7, 2014
                                      4. Heo SH et al: Review of ovarian tumors in children and adolescents: radiologic-pathologic correlation. Radiographics. 34(7):2039-55, 2014
                                      5. Nayak S et al: Vaginal foreign body: a delayed diagnosis. J Pediatr Adolesc Gynecol. 27(6):e127-9, 2014
                                      6. Tinggaard J et al: Ovarian morphology and function during growth hormone therapy of short girls born small for gestational age. Fertil Steril. 102(6):1733-41, 2014
                                      7. Eksioglu AS et al: Value of pelvic sonography in the diagnosis of various forms of precocious puberty in girls. J Clin Ultrasound. 41(2):84-93, 2013
                                      8. Pienkowski C et al: Ovarian cysts in prepubertal girls. Endocr Dev. 22:101-11, 2012
                                      9. Cleemann L et al: Uterus and ovaries in girls and young women with Turner syndrome evaluated by ultrasound and magnetic resonance imaging. Clin Endocrinol (Oxf). 74(6):756-61, 2011
                                      10. Razzaghy-Azar M et al: Sonographic measurement of uterus and ovaries in premenarcheal healthy girls between 6 and 13 years old: correlation with age and pubertal status. J Clin Ultrasound. 39(2):64-73, 2011
                                      11. Sathasivam A et al: Pelvic ultrasonography in the evaluation of central precocious puberty: comparison with leuprolide stimulation test. J Pediatr. 159(3):490-5, 2011
                                      12. Garel L et al: US of the pediatric female pelvis: a clinical perspective. Radiographics. 21(6):1393-407, 2001