Bookmarks
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
- Uveal melanoma, ocular adnexal melanoma, choroidal melanoma
Definitions
- Primary malignancy of uveal tract
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Luke JJ et al: Biology of advanced uveal melanoma and next steps for clinical therapeutics. Pigment Cell Melanoma Res. 28(2):135-47, 2015
- Mashayekhi A et al: Primary transpupillary thermotherapy for choroidal melanoma in 391 cases: importance of risk factors in tumor control. Ophthalmology. 122(3):600-9, 2015
- Matsuo T et al: Clinicopathological correlation for the role of fluorodeoxyglucose positron emission tomography computed tomography in detection of choroidal malignant melanoma. Int J Clin Oncol. 19(2):230-9, 2014
- McCannel TA et al: Association of positive dual-modality positron emission tomography/computed tomography imaging of primary choroidal melanoma with chromosome 3 loss and tumor size. Retina. 30(1):146-51, 2010
- Harbour JW: Molecular prognostic testing and individualized patient care in uveal melanoma. Am J Ophthalmol. 148(6):823-9, 2009
- Modorati G et al: Gamma knife radiosurgery for uveal melanoma: 12 years of experience. Br J Ophthalmol. 93(1):40-4, 2009
- Shildkrot Y et al: Update on posterior uveal melanoma: treatment of the eye and emerging strategies in the prognosis and treatment of metastatic disease. Curr Opin Ophthalmol. 20(6):504-10, 2009
- Coupland SE et al: Routes of extraocular extension of uveal melanoma: risk factors and influence on survival probability. Ophthalmology. 115(10):1778-85, 2008
- Koutsandrea C et al: Metastasis rates and sites after treatment for choroidal melanoma by proton beam irradiation or by enucleation. Clin Ophthalmol. 2(4):989-95, 2008
- Krohn J et al: Posterior uveal melanoma. Distribution of the sites of origin and patterns of tumour extent in the ocular fundus. Br J Ophthalmol. 92(6):751-6, 2008
- Collaborative Ocular Melanoma Study Group: The COMS randomized trial of iodine 125 brachytherapy for choroidal melanoma: V. Twelve-year mortality rates and prognostic factors: COMS report No. 28. Arch Ophthalmol. 124(12):1684-93, 2006
- Lindegaard J et al: Optic nerve invasion of uveal melanoma: clinical characteristics and metastatic pattern. Invest Ophthalmol Vis Sci. 47(8):3268-75, 2006
- Reddy S et al: PET/CT imaging: detection of choroidal melanoma. Br J Ophthalmol. 89(10):1265-9, 2005
- Shields CL et al: Primary transpupillary thermotherapy for small choroidal melanoma in 256 consecutive cases: outcomes and limitations. Ophthalmology. 109(2):225-34, 2002
- Lemke AJ et al: Uveal melanoma: correlation of histopathologic and radiologic findings by using thin-section MR imaging with a surface coil. Radiology. 210(3):775-83, 1999
- Mafee MF: Uveal melanoma, choroidal hemangioma, and simulating lesions. Role of MR imaging. Radiol Clin North Am. 36(6):1083-99, 1998
- Stroszczynski C et al: Choroidal hemangioma: MR findings and differentiation from uveal melanoma. AJNR Am J Neuroradiol. 19(8):1441-7, 1998
- Hosten N et al: Uveal melanoma: detection of extraocular growth with MR imaging and US. Radiology. 202(1):61-7, 1997
- Tong KA et al: Ocular melanoma. AJNR Am J Neuroradiol. 14(6):1359-66, 1993
- McLean IW et al: Modifications of Callender's classification of uveal melanoma at the Armed Forces Institute of Pathology. Am J Ophthalmol. 96(4):502-9, 1983
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
- Uveal melanoma, ocular adnexal melanoma, choroidal melanoma
Definitions
- Primary malignancy of uveal tract
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Luke JJ et al: Biology of advanced uveal melanoma and next steps for clinical therapeutics. Pigment Cell Melanoma Res. 28(2):135-47, 2015
- Mashayekhi A et al: Primary transpupillary thermotherapy for choroidal melanoma in 391 cases: importance of risk factors in tumor control. Ophthalmology. 122(3):600-9, 2015
- Matsuo T et al: Clinicopathological correlation for the role of fluorodeoxyglucose positron emission tomography computed tomography in detection of choroidal malignant melanoma. Int J Clin Oncol. 19(2):230-9, 2014
- McCannel TA et al: Association of positive dual-modality positron emission tomography/computed tomography imaging of primary choroidal melanoma with chromosome 3 loss and tumor size. Retina. 30(1):146-51, 2010
- Harbour JW: Molecular prognostic testing and individualized patient care in uveal melanoma. Am J Ophthalmol. 148(6):823-9, 2009
- Modorati G et al: Gamma knife radiosurgery for uveal melanoma: 12 years of experience. Br J Ophthalmol. 93(1):40-4, 2009
- Shildkrot Y et al: Update on posterior uveal melanoma: treatment of the eye and emerging strategies in the prognosis and treatment of metastatic disease. Curr Opin Ophthalmol. 20(6):504-10, 2009
- Coupland SE et al: Routes of extraocular extension of uveal melanoma: risk factors and influence on survival probability. Ophthalmology. 115(10):1778-85, 2008
- Koutsandrea C et al: Metastasis rates and sites after treatment for choroidal melanoma by proton beam irradiation or by enucleation. Clin Ophthalmol. 2(4):989-95, 2008
- Krohn J et al: Posterior uveal melanoma. Distribution of the sites of origin and patterns of tumour extent in the ocular fundus. Br J Ophthalmol. 92(6):751-6, 2008
- Collaborative Ocular Melanoma Study Group: The COMS randomized trial of iodine 125 brachytherapy for choroidal melanoma: V. Twelve-year mortality rates and prognostic factors: COMS report No. 28. Arch Ophthalmol. 124(12):1684-93, 2006
- Lindegaard J et al: Optic nerve invasion of uveal melanoma: clinical characteristics and metastatic pattern. Invest Ophthalmol Vis Sci. 47(8):3268-75, 2006
- Reddy S et al: PET/CT imaging: detection of choroidal melanoma. Br J Ophthalmol. 89(10):1265-9, 2005
- Shields CL et al: Primary transpupillary thermotherapy for small choroidal melanoma in 256 consecutive cases: outcomes and limitations. Ophthalmology. 109(2):225-34, 2002
- Lemke AJ et al: Uveal melanoma: correlation of histopathologic and radiologic findings by using thin-section MR imaging with a surface coil. Radiology. 210(3):775-83, 1999
- Mafee MF: Uveal melanoma, choroidal hemangioma, and simulating lesions. Role of MR imaging. Radiol Clin North Am. 36(6):1083-99, 1998
- Stroszczynski C et al: Choroidal hemangioma: MR findings and differentiation from uveal melanoma. AJNR Am J Neuroradiol. 19(8):1441-7, 1998
- Hosten N et al: Uveal melanoma: detection of extraocular growth with MR imaging and US. Radiology. 202(1):61-7, 1997
- Tong KA et al: Ocular melanoma. AJNR Am J Neuroradiol. 14(6):1359-66, 1993
- McLean IW et al: Modifications of Callender's classification of uveal melanoma at the Armed Forces Institute of Pathology. Am J Ophthalmol. 96(4):502-9, 1983
