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OPLL
B.J. Manaster, MD, PhD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Clinical Issues

        • Diagnostic Checklist

          TERMINOLOGY

          • Synonyms

            • Ossification posterior longitudinal ligament (OPLL)
          • Definitions

            • Replacement of posterior longitudinal ligamentous tissue by ectopic new bone

          IMAGING

          • General Features

            • Imaging Recommendations

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Fujimori T et al: Ossification of the posterior longitudinal ligament of the cervical spine in 3161 patients: A CT-based study. Spine (Phila Pa 1976). 40(7):E394-403, 2015
                                          2. Nouri A et al: Degenerative cervical myelopathy: epidemiology, genetics and pathogenesis. Spine (Phila Pa 1976). ePub, 2015
                                          3. Yang H et al: Implications of different patterns of "double-layer sign" in cervical ossification of the posterior longitudinal ligament. Eur Spine J. ePub, 2015
                                          4. Tokuhashi Y et al: A patient with two re-surgeries for delayed myelopathy due to progression of ossification of the posterior longitudinal ligaments after cervical laminoplasty. Spine. 34(2):E101-5, 2009
                                          5. Kawaguchi Y et al: Characteristics of ossified lesions in the upper cervical spine associated with ossification of the posterior longitudinal ligament in the lower cervical spine. J Bone Joint Surg Am. 90(4):748-53, 2008
                                          6. Li H et al: A review of prognostic factors for surgical outcome of ossification of the posterior longitudinal ligament of cervical spine. Eur Spine J. 17(10):1277-88, 2008
                                          7. Matsunaga S et al: Radiographic predictors for the development of myelopathy in patients with ossification of the posterior longitudinal ligament: a multicenter cohort study. Spine. 33(24):2648-50, 2008
                                          8. Park JY et al: Thoracic ligament ossification in patients with cervical ossification of the posterior longitudinal ligaments: tandem ossification in the cervical and thoracic spine. Spine. 33(13):E407-10, 2008
                                          9. Iwasaki M et al: Surgical strategy for cervical myelopathy due to ossification of the posterior longitudinal ligament: Part 1: Clinical results and limitations of laminoplasty. Spine. 32(6):647-53, 2007
                                          10. Iwasaki M et al: Surgical strategy for cervical myelopathy due to ossification of the posterior longitudinal ligament: Part 2: Advantages of anterior decompression and fusion over laminoplasty. Spine. 32(6):654-60, 2007
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Clinical Issues

                                                • Diagnostic Checklist

                                                  TERMINOLOGY

                                                  • Synonyms

                                                    • Ossification posterior longitudinal ligament (OPLL)
                                                  • Definitions

                                                    • Replacement of posterior longitudinal ligamentous tissue by ectopic new bone

                                                  IMAGING

                                                  • General Features

                                                    • Imaging Recommendations

                                                      • Radiographic Findings

                                                        • CT Findings

                                                          • MR Findings

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Staging, Grading, & Classification

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Fujimori T et al: Ossification of the posterior longitudinal ligament of the cervical spine in 3161 patients: A CT-based study. Spine (Phila Pa 1976). 40(7):E394-403, 2015
                                                                                  2. Nouri A et al: Degenerative cervical myelopathy: epidemiology, genetics and pathogenesis. Spine (Phila Pa 1976). ePub, 2015
                                                                                  3. Yang H et al: Implications of different patterns of "double-layer sign" in cervical ossification of the posterior longitudinal ligament. Eur Spine J. ePub, 2015
                                                                                  4. Tokuhashi Y et al: A patient with two re-surgeries for delayed myelopathy due to progression of ossification of the posterior longitudinal ligaments after cervical laminoplasty. Spine. 34(2):E101-5, 2009
                                                                                  5. Kawaguchi Y et al: Characteristics of ossified lesions in the upper cervical spine associated with ossification of the posterior longitudinal ligament in the lower cervical spine. J Bone Joint Surg Am. 90(4):748-53, 2008
                                                                                  6. Li H et al: A review of prognostic factors for surgical outcome of ossification of the posterior longitudinal ligament of cervical spine. Eur Spine J. 17(10):1277-88, 2008
                                                                                  7. Matsunaga S et al: Radiographic predictors for the development of myelopathy in patients with ossification of the posterior longitudinal ligament: a multicenter cohort study. Spine. 33(24):2648-50, 2008
                                                                                  8. Park JY et al: Thoracic ligament ossification in patients with cervical ossification of the posterior longitudinal ligaments: tandem ossification in the cervical and thoracic spine. Spine. 33(13):E407-10, 2008
                                                                                  9. Iwasaki M et al: Surgical strategy for cervical myelopathy due to ossification of the posterior longitudinal ligament: Part 1: Clinical results and limitations of laminoplasty. Spine. 32(6):647-53, 2007
                                                                                  10. Iwasaki M et al: Surgical strategy for cervical myelopathy due to ossification of the posterior longitudinal ligament: Part 2: Advantages of anterior decompression and fusion over laminoplasty. Spine. 32(6):654-60, 2007