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KEY FACTS
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Optic neuritis (ON)
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Other Modalities
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
- Marques IB et al: Risk of multiple sclerosis after optic neuritis in patients with normal baseline brain MRI. J Clin Neurosci. 21(4):583-6, 2014
- Toosy AT et al: Optic neuritis. Lancet Neurol. 13(1):83-99, 2014
- He M et al: The use of diffusion MRI in ischemic optic neuropathy and optic neuritis. Semin Ophthalmol. 25(5-6):225-32, 2010
- Swanton JK et al: Early MRI in optic neuritis: the risk for clinically definite multiple sclerosis. Mult Scler. 16(2):156-65, 2010
- Alper G et al: Demyelinating optic neuritis in children. J Child Neurol. 24(1):45-8, 2009
- Bonhomme GR et al: Pediatric optic neuritis: brain MRI abnormalities and risk of multiple sclerosis. Neurology. 72(10):881-5, 2009
- Osborne BJ et al: Optic neuritis and risk of MS: differential diagnosis and management. Cleve Clin J Med. 76(3):181-90, 2009
- Swanton JK et al: Early MRI in optic neuritis: the risk for disability. Neurology. 72(6):542-50, 2009
- Matiello M et al: NMO-IgG predicts the outcome of recurrent optic neuritis. Neurology. 70(23):2197-200, 2008
- Optic Neuritis Study Group: Multiple sclerosis risk after optic neuritis: final optic neuritis treatment trial follow-up. Arch Neurol. 65(6):727-32, 2008
- Volpe NJ: The optic neuritis treatment trial: a definitive answer and profound impact with unexpected results. Arch Ophthalmol. 126(7):996-9, 2008
- Al-Shafai LS et al: Diffusion MR imaging in a case of acute ischemic optic neuropathy. AJNR Am J Neuroradiol. 27(2):255-7, 2006
- Wilejto M et al: The clinical features, MRI findings, and outcome of optic neuritis in children. Neurology. 67(2):258-62, 2006
- Wingerchuk DM et al: Revised diagnostic criteria for neuromyelitis optica. Neurology. 66(10):1485-9, 2006
- Hickman SJ et al: Optic nerve diffusion measurement from diffusion-weighted imaging in optic neuritis. AJNR Am J Neuroradiol. 26(4):951-6, 2005
- Beck RW et al: Visual function more than 10 years after optic neuritis: experience of the optic neuritis treatment trial. Am J Ophthalmol. 137(1):77-83, 2004
- Hickman SJ et al: Management of acute optic neuritis. Lancet. 360(9349):1953-62, 2002
- Rizzo JF 3rd et al: Use of magnetic resonance imaging to differentiate optic neuritis and nonarteritic anterior ischemic optic neuropathy. Ophthalmology. 109(9):1679-84, 2002
- Kaufman DI et al: Practice parameter: the role of corticosteroids in the management of acute monosymptomatic optic neuritis. Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 54(11):2039-44, 2000
- Sorensen TL et al: Optic neuritis as onset manifestation of multiple sclerosis: a nationwide, long-term survey. Neurology. 53(3):473-8, 1999
- Hudgins PA et al: Radiation-induced optic neuropathy: characteristic appearances on gadolinium-enhanced MR. AJNR Am J Neuroradiol. 13(1):235-8, 1992
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References
Tables
Tables
KEY FACTS
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Optic neuritis (ON)
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Other Modalities
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
- Marques IB et al: Risk of multiple sclerosis after optic neuritis in patients with normal baseline brain MRI. J Clin Neurosci. 21(4):583-6, 2014
- Toosy AT et al: Optic neuritis. Lancet Neurol. 13(1):83-99, 2014
- He M et al: The use of diffusion MRI in ischemic optic neuropathy and optic neuritis. Semin Ophthalmol. 25(5-6):225-32, 2010
- Swanton JK et al: Early MRI in optic neuritis: the risk for clinically definite multiple sclerosis. Mult Scler. 16(2):156-65, 2010
- Alper G et al: Demyelinating optic neuritis in children. J Child Neurol. 24(1):45-8, 2009
- Bonhomme GR et al: Pediatric optic neuritis: brain MRI abnormalities and risk of multiple sclerosis. Neurology. 72(10):881-5, 2009
- Osborne BJ et al: Optic neuritis and risk of MS: differential diagnosis and management. Cleve Clin J Med. 76(3):181-90, 2009
- Swanton JK et al: Early MRI in optic neuritis: the risk for disability. Neurology. 72(6):542-50, 2009
- Matiello M et al: NMO-IgG predicts the outcome of recurrent optic neuritis. Neurology. 70(23):2197-200, 2008
- Optic Neuritis Study Group: Multiple sclerosis risk after optic neuritis: final optic neuritis treatment trial follow-up. Arch Neurol. 65(6):727-32, 2008
- Volpe NJ: The optic neuritis treatment trial: a definitive answer and profound impact with unexpected results. Arch Ophthalmol. 126(7):996-9, 2008
- Al-Shafai LS et al: Diffusion MR imaging in a case of acute ischemic optic neuropathy. AJNR Am J Neuroradiol. 27(2):255-7, 2006
- Wilejto M et al: The clinical features, MRI findings, and outcome of optic neuritis in children. Neurology. 67(2):258-62, 2006
- Wingerchuk DM et al: Revised diagnostic criteria for neuromyelitis optica. Neurology. 66(10):1485-9, 2006
- Hickman SJ et al: Optic nerve diffusion measurement from diffusion-weighted imaging in optic neuritis. AJNR Am J Neuroradiol. 26(4):951-6, 2005
- Beck RW et al: Visual function more than 10 years after optic neuritis: experience of the optic neuritis treatment trial. Am J Ophthalmol. 137(1):77-83, 2004
- Hickman SJ et al: Management of acute optic neuritis. Lancet. 360(9349):1953-62, 2002
- Rizzo JF 3rd et al: Use of magnetic resonance imaging to differentiate optic neuritis and nonarteritic anterior ischemic optic neuropathy. Ophthalmology. 109(9):1679-84, 2002
- Kaufman DI et al: Practice parameter: the role of corticosteroids in the management of acute monosymptomatic optic neuritis. Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 54(11):2039-44, 2000
- Sorensen TL et al: Optic neuritis as onset manifestation of multiple sclerosis: a nationwide, long-term survey. Neurology. 53(3):473-8, 1999
- Hudgins PA et al: Radiation-induced optic neuropathy: characteristic appearances on gadolinium-enhanced MR. AJNR Am J Neuroradiol. 13(1):235-8, 1992
