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Oral Cavity Dermoid and Epidermoid
Daniel E. Meltzer, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Synonyms

              • Developmental oral cavity (OC) cyst, ectodermal inclusion cyst, dermoid cyst
            • Definitions

              • Cystic OC lesion resulting from congenital epithelial inclusion or rest
                • Dermoid: Epithelial elements + dermal adnexa
                • Epidermoid: Epithelial elements only
              • Rarer entity is teratoid cyst
                • Epithelial elements + other tissue, such as bone, cartilage, or muscle

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Staging, Grading, & Classification

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Sauer A et al: A pediatric lateral submental mass: a rare presentation of dermoid cyst. Ear Nose Throat J. 1455613211019787, 2021
                                            2. Abdel Razek AAK et al: Differentiation of sublingual thyroglossal duct cyst from midline dermoid cyst with diffusion weighted imaging. Int J Pediatr Otorhinolaryngol. 126:109623, 2019
                                            3. Giarraputo L et al: Dermoid cyst of the floor of the mouth: diagnostic imaging findings. Cureus. 10(4):e2403, 2018
                                            4. Ueno T et al: Epidermoid cyst arising on the body of the tongue: case report and literature review. J Nippon Med Sch. 85(6):343-6, 2018
                                            5. Puricelli E et al: Occurrence of dermoid cyst in the floor of the mouth: the importance of differential diagnosis in pediatric patients. J Appl Oral Sci. 25(3):341-5, 2017
                                            6. Baliga M et al: Epidermoid cyst of the floor of the mouth. Natl J Maxillofac Surg. 5(1):79-83, 2014
                                            7. Beil CM et al: Oral and oropharyngeal tumors. Eur J Radiol. 66(3):448-59, 2008
                                            8. Fujimoto N et al: Dermoid cyst with magnetic resonance image of sack-of-marbles. Br J Dermatol. 158(2):415-7, 2008
                                            9. Kandogan T et al: Sublingual epidermoid cyst: a case report. J Med Case Reports. 1:87, 2007
                                            10. Göl IH et al: Congenital sublingual teratoid cyst: a case report and literature review. J Pediatr Surg. 40(5):e9-e12, 2005
                                            11. Ho MW et al: Simultaneous occurrence of sublingual dermoid cyst and oral alimentary tract cyst in an infant: a case report and review of the literature. Int J Paediatr Dent. 13(6):441-6, 2003
                                            12. Longo F et al: Midline (dermoid) cysts of the floor of the mouth: report of 16 cases and review of surgical techniques. Plast Reconstr Surg. 112(6):1560-5, 2003
                                            13. Mathews J et al: True lateral dermoid cyst of the floor of the mouth. J Laryngol Otol. 115(4):333-5, 2001
                                            14. Myssiorek D et al: Intralingual dermoid cysts: a report of two new cases. Ear Nose Throat J. 79(5):380-3, 2000
                                            15. Godden DR et al: Sliding dermoid cyst. A case report. Int J Oral Maxillofac Surg. 28(6):459-60, 1999
                                            16. Miles LP et al: Congenital dermoid cyst of the tongue. J Laryngol Otol. 111(12):1179-82, 1997
                                            17. Oygur T et al: Oral congenital dermoid cyst in the floor of the mouth of a newborn. The significance of gastrointestinal-type epithelium. Oral Surg Oral Med Oral Pathol. 74(5):627-30, 1992
                                            18. Tuffin JR et al: True lateral dermoid cyst of the neck. Int J Oral Maxillofac Surg. 20(5):275-6, 1991
                                            19. al-Khayat M et al: Midline sublingual dermoid cyst. J Laryngol Otol. 104(7):578-80, 1990
                                            20. Hagberg JM et al: Pulmonary function in young and older athletes and untrained men. J Appl Physiol (1985). 65(1):101-5, 1988
                                            21. Gibson WS Jr et al: Congenital sublingual dermoid cyst. Arch Otolaryngol. 108(11):745-8, 1982
                                            22. Meyer I: Dermoid cysts (dermoids) of the floor of the mouth. J Oral Surg (Chic). 8(11):1149-64, 1955
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Synonyms

                                                        • Developmental oral cavity (OC) cyst, ectodermal inclusion cyst, dermoid cyst
                                                      • Definitions

                                                        • Cystic OC lesion resulting from congenital epithelial inclusion or rest
                                                          • Dermoid: Epithelial elements + dermal adnexa
                                                          • Epidermoid: Epithelial elements only
                                                        • Rarer entity is teratoid cyst
                                                          • Epithelial elements + other tissue, such as bone, cartilage, or muscle

                                                      IMAGING

                                                      • General Features

                                                        • CT Findings

                                                          • MR Findings

                                                            • Ultrasonographic Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Staging, Grading, & Classification

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  DIAGNOSTIC CHECKLIST

                                                                                  • Consider

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Sauer A et al: A pediatric lateral submental mass: a rare presentation of dermoid cyst. Ear Nose Throat J. 1455613211019787, 2021
                                                                                      2. Abdel Razek AAK et al: Differentiation of sublingual thyroglossal duct cyst from midline dermoid cyst with diffusion weighted imaging. Int J Pediatr Otorhinolaryngol. 126:109623, 2019
                                                                                      3. Giarraputo L et al: Dermoid cyst of the floor of the mouth: diagnostic imaging findings. Cureus. 10(4):e2403, 2018
                                                                                      4. Ueno T et al: Epidermoid cyst arising on the body of the tongue: case report and literature review. J Nippon Med Sch. 85(6):343-6, 2018
                                                                                      5. Puricelli E et al: Occurrence of dermoid cyst in the floor of the mouth: the importance of differential diagnosis in pediatric patients. J Appl Oral Sci. 25(3):341-5, 2017
                                                                                      6. Baliga M et al: Epidermoid cyst of the floor of the mouth. Natl J Maxillofac Surg. 5(1):79-83, 2014
                                                                                      7. Beil CM et al: Oral and oropharyngeal tumors. Eur J Radiol. 66(3):448-59, 2008
                                                                                      8. Fujimoto N et al: Dermoid cyst with magnetic resonance image of sack-of-marbles. Br J Dermatol. 158(2):415-7, 2008
                                                                                      9. Kandogan T et al: Sublingual epidermoid cyst: a case report. J Med Case Reports. 1:87, 2007
                                                                                      10. Göl IH et al: Congenital sublingual teratoid cyst: a case report and literature review. J Pediatr Surg. 40(5):e9-e12, 2005
                                                                                      11. Ho MW et al: Simultaneous occurrence of sublingual dermoid cyst and oral alimentary tract cyst in an infant: a case report and review of the literature. Int J Paediatr Dent. 13(6):441-6, 2003
                                                                                      12. Longo F et al: Midline (dermoid) cysts of the floor of the mouth: report of 16 cases and review of surgical techniques. Plast Reconstr Surg. 112(6):1560-5, 2003
                                                                                      13. Mathews J et al: True lateral dermoid cyst of the floor of the mouth. J Laryngol Otol. 115(4):333-5, 2001
                                                                                      14. Myssiorek D et al: Intralingual dermoid cysts: a report of two new cases. Ear Nose Throat J. 79(5):380-3, 2000
                                                                                      15. Godden DR et al: Sliding dermoid cyst. A case report. Int J Oral Maxillofac Surg. 28(6):459-60, 1999
                                                                                      16. Miles LP et al: Congenital dermoid cyst of the tongue. J Laryngol Otol. 111(12):1179-82, 1997
                                                                                      17. Oygur T et al: Oral congenital dermoid cyst in the floor of the mouth of a newborn. The significance of gastrointestinal-type epithelium. Oral Surg Oral Med Oral Pathol. 74(5):627-30, 1992
                                                                                      18. Tuffin JR et al: True lateral dermoid cyst of the neck. Int J Oral Maxillofac Surg. 20(5):275-6, 1991
                                                                                      19. al-Khayat M et al: Midline sublingual dermoid cyst. J Laryngol Otol. 104(7):578-80, 1990
                                                                                      20. Hagberg JM et al: Pulmonary function in young and older athletes and untrained men. J Appl Physiol (1985). 65(1):101-5, 1988
                                                                                      21. Gibson WS Jr et al: Congenital sublingual dermoid cyst. Arch Otolaryngol. 108(11):745-8, 1982
                                                                                      22. Meyer I: Dermoid cysts (dermoids) of the floor of the mouth. J Oral Surg (Chic). 8(11):1149-64, 1955