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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Oral cavity minor salivary gland malignancy (MSGM)
Definitions
- Primary minor salivary gland malignancy
- Located in submucosa upper aerodigestive tract
- Most common MSGM: Adenoid cystic carcinoma (ACCa) and mucoepidermoid carcinoma (MECa)
- Primary minor salivary gland malignancy
IMAGING
General Features
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
- Sarma M et al: Pleomorphic adenoma of tongue: a case report. Indian J Otolaryngol Head Neck Surg. 72(1):145-7, 2020
- Singh M et al: Utility of fine needle aspiration in diagnosis of intraoral minor salivary gland tumors. J Cytol. 37(1):53-7, 2020
- Buch SA et al: A rare case of long-standing mucoepidermoid carcinoma of minor salivary glands of the palate. Stomatologija. 21(3):92-6, 2019
- Hay AJ et al: Minor salivary gland tumors of the head and neck-Memorial Sloan Kettering experience: Incidence and outcomes by site and histological type. Cancer. ePub, 2019
- Hämetoja H et al: Polyomavirus JCPyV infrequently detectable in adenoid cystic carcinoma of the oral cavity and the airways. Virchows Arch. 475(5):609-16, 2019
- Khanna D et al: Carcinoma ex pleomorphic adenoma: a case report and review of literature. Afr Health Sci. 19(4):3253-63, 2019
- Mimica X et al: Polymorphous adenocarcinoma of salivary glands. Oral Oncol. 95:52-8, 2019
- Munhoz L et al: Application of diffusion-weighted magnetic resonance imaging in the diagnosis of salivary gland diseases: a systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol. 128(3):280-310, 2019
- Nawroz I et al: Minor salivary gland intraductal mucoepidermoid carcinoma: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol. 128(1):e13-e15, 2019
- Nonitha S et al: Histomorphological comparison of pleomorphic adenoma in major and minor salivary glands of oral cavity: A comparative study. J Oral Maxillofac Pathol. 23(3):356-62, 2019
- Abdel Razek AAK et al: Imaging of minor salivary glands. Neuroimaging Clin N Am. 28(2):295-302, 2018
- Feng AL et al: Multiple simultaneous head and neck cancers in Lynch syndrome: Case report and literature review. Laryngoscope. 128(12):2759-61, 2018
- Gill S et al: Mucoepidermoid carcinoma of hard palate. Indian J Pathol Microbiol. 61(3):397-8, 2018
- Mokhniuk K et al: Cytological investigation of a first case of basal cell adenocarcinoma arising in the minor salivary glands. Case report and review of the literature. Diagn Cytopathol. 46(8):682-4, 2018
- Roy S et al: Mammary analogue secretory carcinoma of minor salivary glands: A rare case series and review of the literature. Ann Clin Lab Sci. 48(1):94-9, 2018
- von Stempel C et al: Imaging of palatal lumps. Clin Radiol. 72(2):97-107, 2017
- Aydil U et al: Neoplasms of the hard palate. J Oral Maxillofac Surg. 72(3):619-26, 2014
- Kato H et al: CT and MR imaging findings of palatal tumors. Eur J Radiol. 83(3):e137-46, 2014
- Kimple AJ et al: Polymorphous low-grade adenocarcinoma: a case series and determination of recurrence. Laryngoscope. 124(12):2714-9, 2014
- Chuiwa H et al: Minor salivary gland carcinomas of oral cavity and oropharynx. J Laryngol Otol Suppl. (31):52-7, 2009
- Dhanuthai K et al: A clinico-pathologic study of 311 intra-oral salivary gland tumors in Thais. J Oral Pathol Med. 38(6):495-500, 2009
- Mücke T et al: Advanced malignant minor salivary glands tumors of the oral cavity. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 108(1):81-9, 2009
- Agarwal JP et al: Intraoral adenoid cystic carcinoma: prognostic factors and outcome. Oral Oncol. 44(10):986-93, 2008
- Lee YY et al: Imaging of salivary gland tumours. Eur J Radiol. 66(3):419-36, 2008
- Buchner A et al: Relative frequency of intra-oral minor salivary gland tumors: a study of 380 cases from northern California and comparison to reports from other parts of the world. J Oral Pathol Med. 36(4):207-14, 2007
- Pires FR et al: Intra-oral minor salivary gland tumors: a clinicopathological study of 546 cases. Oral Oncol. 43(5):463-70, 2007
- Wang D et al: Intraoral minor salivary gland tumors in a Chinese population: a retrospective study on 737 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 104(1):94-100, 2007
- Yih WY et al: Intraoral minor salivary gland neoplasms: review of 213 cases. J Oral Maxillofac Surg. 63(6):805-10, 2005
- Kolude B et al: Mucoepidermoid carcinoma of the oral cavity. J Natl Med Assoc. 93(5):178-84, 2001
- Lopes MA et al: A clinicopathologic study of 196 intraoral minor salivary gland tumours. J Oral Pathol Med. 28(6):264-7, 1999
- Jones AS et al: Tumours of the minor salivary glands. Clin Otolaryngol Allied Sci. 23(1):27-33, 1998
- Kurabayashi T et al: Differential diagnosis of tumours of the minor salivary glands of the palate by computed tomography. Dentomaxillofac Radiol. 26(1):16-21, 1997
- Parsons JT et al: Management of minor salivary gland carcinomas. Int J Radiat Oncol Biol Phys. 35(3):443-54, 1996
- Beckhardt RN et al: Minor salivary gland tumors of the palate: clinical and pathologic correlates of outcome. Laryngoscope. 105(11):1155-60, 1995
- Garden AS et al: Postoperative radiation therapy for malignant tumors of minor salivary glands. Outcome and patterns of failure. Cancer. 73(10):2563-9, 1994
- Sadeghi A et al: Minor salivary gland tumors of the head and neck: treatment strategies and prognosis. Am J Clin Oncol. 16(1):3-8, 1993
- Spiro RH et al: The importance of clinical staging of minor salivary gland carcinoma. Am J Surg. 162(4):330-6, 1991
- Weber RS et al: Minor salivary gland tumors of the lip and buccal mucosa. Laryngoscope. 99(1):6-9, 1989
- Ellis ER et al: The use of radiation therapy in the management of minor salivary gland tumors. Int J Radiat Oncol Biol Phys. 15(3):613-7, 1988
- Evans HL et al: Polymorphous low-grade adenocarcinoma of minor salivary glands. A study of 14 cases of a distinctive neoplasm. Cancer. 53(4):935-42, 1984
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References
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Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Oral cavity minor salivary gland malignancy (MSGM)
Definitions
- Primary minor salivary gland malignancy
- Located in submucosa upper aerodigestive tract
- Most common MSGM: Adenoid cystic carcinoma (ACCa) and mucoepidermoid carcinoma (MECa)
- Primary minor salivary gland malignancy
IMAGING
General Features
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
- Sarma M et al: Pleomorphic adenoma of tongue: a case report. Indian J Otolaryngol Head Neck Surg. 72(1):145-7, 2020
- Singh M et al: Utility of fine needle aspiration in diagnosis of intraoral minor salivary gland tumors. J Cytol. 37(1):53-7, 2020
- Buch SA et al: A rare case of long-standing mucoepidermoid carcinoma of minor salivary glands of the palate. Stomatologija. 21(3):92-6, 2019
- Hay AJ et al: Minor salivary gland tumors of the head and neck-Memorial Sloan Kettering experience: Incidence and outcomes by site and histological type. Cancer. ePub, 2019
- Hämetoja H et al: Polyomavirus JCPyV infrequently detectable in adenoid cystic carcinoma of the oral cavity and the airways. Virchows Arch. 475(5):609-16, 2019
- Khanna D et al: Carcinoma ex pleomorphic adenoma: a case report and review of literature. Afr Health Sci. 19(4):3253-63, 2019
- Mimica X et al: Polymorphous adenocarcinoma of salivary glands. Oral Oncol. 95:52-8, 2019
- Munhoz L et al: Application of diffusion-weighted magnetic resonance imaging in the diagnosis of salivary gland diseases: a systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol. 128(3):280-310, 2019
- Nawroz I et al: Minor salivary gland intraductal mucoepidermoid carcinoma: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol. 128(1):e13-e15, 2019
- Nonitha S et al: Histomorphological comparison of pleomorphic adenoma in major and minor salivary glands of oral cavity: A comparative study. J Oral Maxillofac Pathol. 23(3):356-62, 2019
- Abdel Razek AAK et al: Imaging of minor salivary glands. Neuroimaging Clin N Am. 28(2):295-302, 2018
- Feng AL et al: Multiple simultaneous head and neck cancers in Lynch syndrome: Case report and literature review. Laryngoscope. 128(12):2759-61, 2018
- Gill S et al: Mucoepidermoid carcinoma of hard palate. Indian J Pathol Microbiol. 61(3):397-8, 2018
- Mokhniuk K et al: Cytological investigation of a first case of basal cell adenocarcinoma arising in the minor salivary glands. Case report and review of the literature. Diagn Cytopathol. 46(8):682-4, 2018
- Roy S et al: Mammary analogue secretory carcinoma of minor salivary glands: A rare case series and review of the literature. Ann Clin Lab Sci. 48(1):94-9, 2018
- von Stempel C et al: Imaging of palatal lumps. Clin Radiol. 72(2):97-107, 2017
- Aydil U et al: Neoplasms of the hard palate. J Oral Maxillofac Surg. 72(3):619-26, 2014
- Kato H et al: CT and MR imaging findings of palatal tumors. Eur J Radiol. 83(3):e137-46, 2014
- Kimple AJ et al: Polymorphous low-grade adenocarcinoma: a case series and determination of recurrence. Laryngoscope. 124(12):2714-9, 2014
- Chuiwa H et al: Minor salivary gland carcinomas of oral cavity and oropharynx. J Laryngol Otol Suppl. (31):52-7, 2009
- Dhanuthai K et al: A clinico-pathologic study of 311 intra-oral salivary gland tumors in Thais. J Oral Pathol Med. 38(6):495-500, 2009
- Mücke T et al: Advanced malignant minor salivary glands tumors of the oral cavity. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 108(1):81-9, 2009
- Agarwal JP et al: Intraoral adenoid cystic carcinoma: prognostic factors and outcome. Oral Oncol. 44(10):986-93, 2008
- Lee YY et al: Imaging of salivary gland tumours. Eur J Radiol. 66(3):419-36, 2008
- Buchner A et al: Relative frequency of intra-oral minor salivary gland tumors: a study of 380 cases from northern California and comparison to reports from other parts of the world. J Oral Pathol Med. 36(4):207-14, 2007
- Pires FR et al: Intra-oral minor salivary gland tumors: a clinicopathological study of 546 cases. Oral Oncol. 43(5):463-70, 2007
- Wang D et al: Intraoral minor salivary gland tumors in a Chinese population: a retrospective study on 737 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 104(1):94-100, 2007
- Yih WY et al: Intraoral minor salivary gland neoplasms: review of 213 cases. J Oral Maxillofac Surg. 63(6):805-10, 2005
- Kolude B et al: Mucoepidermoid carcinoma of the oral cavity. J Natl Med Assoc. 93(5):178-84, 2001
- Lopes MA et al: A clinicopathologic study of 196 intraoral minor salivary gland tumours. J Oral Pathol Med. 28(6):264-7, 1999
- Jones AS et al: Tumours of the minor salivary glands. Clin Otolaryngol Allied Sci. 23(1):27-33, 1998
- Kurabayashi T et al: Differential diagnosis of tumours of the minor salivary glands of the palate by computed tomography. Dentomaxillofac Radiol. 26(1):16-21, 1997
- Parsons JT et al: Management of minor salivary gland carcinomas. Int J Radiat Oncol Biol Phys. 35(3):443-54, 1996
- Beckhardt RN et al: Minor salivary gland tumors of the palate: clinical and pathologic correlates of outcome. Laryngoscope. 105(11):1155-60, 1995
- Garden AS et al: Postoperative radiation therapy for malignant tumors of minor salivary glands. Outcome and patterns of failure. Cancer. 73(10):2563-9, 1994
- Sadeghi A et al: Minor salivary gland tumors of the head and neck: treatment strategies and prognosis. Am J Clin Oncol. 16(1):3-8, 1993
- Spiro RH et al: The importance of clinical staging of minor salivary gland carcinoma. Am J Surg. 162(4):330-6, 1991
- Weber RS et al: Minor salivary gland tumors of the lip and buccal mucosa. Laryngoscope. 99(1):6-9, 1989
- Ellis ER et al: The use of radiation therapy in the management of minor salivary gland tumors. Int J Radiat Oncol Biol Phys. 15(3):613-7, 1988
- Evans HL et al: Polymorphous low-grade adenocarcinoma of minor salivary glands. A study of 14 cases of a distinctive neoplasm. Cancer. 53(4):935-42, 1984
