Orbital capillary hemangioma, infantile periocular hemangioma
Definitions
Benign vascular tumor of infancy
Distinct lesion from vascular malformation
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Angiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
Ford JR et al: Early orbital infantile hemangioma that emphasizes the importance of glucose-transporter-1 (GLUT-1). Can J Ophthalmol. 53(2):e58-60, 2018
Kralik SF et al: Orbital infantile hemangioma and rhabdomyosarcoma in children: differentiation using diffusion-weighted magnetic resonance imaging. J AAPOS. 22(1):27-31, 2018
Stass-Isern M: Periorbital and orbital infantile hemangiomas. Int Ophthalmol Clin. 54(3):73-82, 2014
Xu S et al: Treatment of periorbital infantile haemangiomas: a systematic literature review on propranolol or steroids. J Paediatr Child Health. 50(4):271-9, 2014
Drolet BA et al: Initiation and use of propranolol for infantile hemangioma: report of a consensus conference. Pediatrics. 131(1):128-40, 2013
Frank RC et al: Visual development in infants: visual complications of periocular haemangiomas. J Plast Reconstr Aesthet Surg. 63(1):1-8, 2010
Nguyen J et al: Pharmacologic therapy for periocular infantile hemangiomas: a review of the literature. Semin Ophthalmol. 24(3):178-84, 2009
Chan LK et al: The management of periorbital fat excess in haemangioma involution. J Plast Reconstr Aesthet Surg. 61(2):133-7, 2008
Léauté-Labrèze C et al: Propranolol for severe hemangiomas of infancy. N Engl J Med. 358(24):2649-51, 2008
Tronina SA et al: Combined surgical method of orbital and periorbital hemangioma treatment in infants. Orbit. 27(4):249-57, 2008
Weiss AH et al: Reappraisal of astigmatism induced by periocular capillary hemangioma and treatment with intralesional corticosteroid injection. Ophthalmology. 115(2):390-7, 2008
Chung EM et al: From the archives of the AFIP: pediatric orbit tumors and tumorlike lesions: nonosseous lesions of the extraocular orbit. Radiographics. 27(6):1777-99, 2007
Judd CD et al: Intracranial infantile hemangiomas associated with PHACE syndrome. AJNR Am J Neuroradiol. 28(1):25-9, 2007
Levi M et al: Surgical treatment of capillary hemangiomas causing amblyopia. J AAPOS. 11(3):230-4, 2007
Reddy AR et al: Is this really a capillary haemangioma? Orbit. 26(4):327-9, 2007
Dubois J et al: Orbit and eyelid hemangiomas: is there a relationship between location and ocular problems? J Am Acad Dermatol. 55(4):614-9, 2006
Kavanagh EC et al: Imaging of the natural history of an orbital capillary hemangioma. Orbit. 25(1):69-72, 2006
Schwartz SR et al: Risk factors for amblyopia in children with capillary hemangiomas of the eyelids and orbit. J AAPOS. 10(3):262-8, 2006
Verity DH et al: Natural history of periocular capillary haemangiomas: changes in internal blood velocity and lesion volume. Eye. 20(10):1228-37, 2006
Ersoy S et al: Hemifacial infantile hemangioma with intracranial extension: a rare entity. Pediatr Dermatol. 22(4):309-13, 2005
Neudorfer M et al: Intraorbital and periorbital tumors in children--value of ultrasound and color Doppler imaging in the differential diagnosis. Am J Ophthalmol. 137(6):1065-72, 2004
Castillo BV Jr et al: Pediatric tumors of the eye and orbit. Pediatr Clin North Am. 50(1):149-72, 2003
O'Keefe M et al: Capillary haemangioma of the eyelids and orbit: a clinical review of the safety and efficacy of intralesional steroid. Acta Ophthalmol Scand. 81(3):294-8, 2003
Rootman J: Vascular malformations of the orbit: hemodynamic concepts. Orbit. 22(2):103-20, 2003
Waner M et al: The nonrandom distribution of facial hemangiomas. Arch Dermatol. 139(7):869-75, 2003
Sleep TJ et al: Doppler ultrasonography to aid diagnosis of orbital capillary haemangioma in neonates. Eye. 16(3):316-9, 2002
Bilaniuk LT: Orbital vascular lesions. Role of imaging. Radiol Clin North Am. 37(1):169-83, xi, 1999
Harris GJ: Orbital vascular malformations: a consensus statement on terminology and its clinical implications. Orbital Society. Am J Ophthalmol. 127(4):453-5, 1999
Walter JW et al: Genetic mapping of a novel familial form of infantile hemangioma. Am J Med Genet. 82(1):77-83, 1999
Forbes G: Vascular lesions in the orbit. Neuroimaging Clin N Am. 6(1):113-22, 1996
Rootman J et al: Multidisciplinary approaches to complicated vascular lesions of the orbit. Ophthalmology. 99(9):1440-6, 1992
Mafee MF et al: Dynamic computed tomography and its application to ophthalmology. Radiol Clin North Am. 25(4):715-31, 1987
Mafee MF et al: Orbital space-occupying lesions: role of computed tomography and magnetic resonance imaging. An analysis of 145 cases. Radiol Clin North Am. 25(3):529-59, 1987
Sklar EL et al: Correlative study of the computed tomographic, ultrasonographic, and pathological characteristics of cavernous versus capillary hemangiomas of the orbit. J Clin Neuroophthalmol. 6(1):14-21, 1986
Mulliken JB et al: Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics. Plast Reconstr Surg. 69(3):412-22, 1982
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
Orbital capillary hemangioma, infantile periocular hemangioma
Definitions
Benign vascular tumor of infancy
Distinct lesion from vascular malformation
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Angiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
Ford JR et al: Early orbital infantile hemangioma that emphasizes the importance of glucose-transporter-1 (GLUT-1). Can J Ophthalmol. 53(2):e58-60, 2018
Kralik SF et al: Orbital infantile hemangioma and rhabdomyosarcoma in children: differentiation using diffusion-weighted magnetic resonance imaging. J AAPOS. 22(1):27-31, 2018
Stass-Isern M: Periorbital and orbital infantile hemangiomas. Int Ophthalmol Clin. 54(3):73-82, 2014
Xu S et al: Treatment of periorbital infantile haemangiomas: a systematic literature review on propranolol or steroids. J Paediatr Child Health. 50(4):271-9, 2014
Drolet BA et al: Initiation and use of propranolol for infantile hemangioma: report of a consensus conference. Pediatrics. 131(1):128-40, 2013
Frank RC et al: Visual development in infants: visual complications of periocular haemangiomas. J Plast Reconstr Aesthet Surg. 63(1):1-8, 2010
Nguyen J et al: Pharmacologic therapy for periocular infantile hemangiomas: a review of the literature. Semin Ophthalmol. 24(3):178-84, 2009
Chan LK et al: The management of periorbital fat excess in haemangioma involution. J Plast Reconstr Aesthet Surg. 61(2):133-7, 2008
Léauté-Labrèze C et al: Propranolol for severe hemangiomas of infancy. N Engl J Med. 358(24):2649-51, 2008
Tronina SA et al: Combined surgical method of orbital and periorbital hemangioma treatment in infants. Orbit. 27(4):249-57, 2008
Weiss AH et al: Reappraisal of astigmatism induced by periocular capillary hemangioma and treatment with intralesional corticosteroid injection. Ophthalmology. 115(2):390-7, 2008
Chung EM et al: From the archives of the AFIP: pediatric orbit tumors and tumorlike lesions: nonosseous lesions of the extraocular orbit. Radiographics. 27(6):1777-99, 2007
Judd CD et al: Intracranial infantile hemangiomas associated with PHACE syndrome. AJNR Am J Neuroradiol. 28(1):25-9, 2007
Levi M et al: Surgical treatment of capillary hemangiomas causing amblyopia. J AAPOS. 11(3):230-4, 2007
Reddy AR et al: Is this really a capillary haemangioma? Orbit. 26(4):327-9, 2007
Dubois J et al: Orbit and eyelid hemangiomas: is there a relationship between location and ocular problems? J Am Acad Dermatol. 55(4):614-9, 2006
Kavanagh EC et al: Imaging of the natural history of an orbital capillary hemangioma. Orbit. 25(1):69-72, 2006
Schwartz SR et al: Risk factors for amblyopia in children with capillary hemangiomas of the eyelids and orbit. J AAPOS. 10(3):262-8, 2006
Verity DH et al: Natural history of periocular capillary haemangiomas: changes in internal blood velocity and lesion volume. Eye. 20(10):1228-37, 2006
Ersoy S et al: Hemifacial infantile hemangioma with intracranial extension: a rare entity. Pediatr Dermatol. 22(4):309-13, 2005
Neudorfer M et al: Intraorbital and periorbital tumors in children--value of ultrasound and color Doppler imaging in the differential diagnosis. Am J Ophthalmol. 137(6):1065-72, 2004
Castillo BV Jr et al: Pediatric tumors of the eye and orbit. Pediatr Clin North Am. 50(1):149-72, 2003
O'Keefe M et al: Capillary haemangioma of the eyelids and orbit: a clinical review of the safety and efficacy of intralesional steroid. Acta Ophthalmol Scand. 81(3):294-8, 2003
Rootman J: Vascular malformations of the orbit: hemodynamic concepts. Orbit. 22(2):103-20, 2003
Waner M et al: The nonrandom distribution of facial hemangiomas. Arch Dermatol. 139(7):869-75, 2003
Sleep TJ et al: Doppler ultrasonography to aid diagnosis of orbital capillary haemangioma in neonates. Eye. 16(3):316-9, 2002
Bilaniuk LT: Orbital vascular lesions. Role of imaging. Radiol Clin North Am. 37(1):169-83, xi, 1999
Harris GJ: Orbital vascular malformations: a consensus statement on terminology and its clinical implications. Orbital Society. Am J Ophthalmol. 127(4):453-5, 1999
Walter JW et al: Genetic mapping of a novel familial form of infantile hemangioma. Am J Med Genet. 82(1):77-83, 1999
Forbes G: Vascular lesions in the orbit. Neuroimaging Clin N Am. 6(1):113-22, 1996
Rootman J et al: Multidisciplinary approaches to complicated vascular lesions of the orbit. Ophthalmology. 99(9):1440-6, 1992
Mafee MF et al: Dynamic computed tomography and its application to ophthalmology. Radiol Clin North Am. 25(4):715-31, 1987
Mafee MF et al: Orbital space-occupying lesions: role of computed tomography and magnetic resonance imaging. An analysis of 145 cases. Radiol Clin North Am. 25(3):529-59, 1987
Sklar EL et al: Correlative study of the computed tomographic, ultrasonographic, and pathological characteristics of cavernous versus capillary hemangiomas of the orbit. J Clin Neuroophthalmol. 6(1):14-21, 1986
Mulliken JB et al: Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics. Plast Reconstr Surg. 69(3):412-22, 1982
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