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Orbital Sarcoidosis
H. Christian Davidson, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Definitions

                • Noncaseating granulomatous inflammation of orbit
                • Orbital sarcoid reaction = involvement limited to orbit without systemic disease

              IMAGING

              • General Features

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      • Nuclear Medicine Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Rosenbaum JT et al: Parallel gene expression changes in sarcoidosis involving the lacrimal gland, orbital tissue, or blood. JAMA Ophthalmol. 133(7):770-7, 2015
                                            2. Demirci H et al: Orbital and adnexal involvement in sarcoidosis: analysis of clinical features and systemic disease in 30 cases. Am J Ophthalmol. 151(6):1074-1080, 2011
                                            3. Mavrikakis I et al: Diverse clinical presentations of orbital sarcoid. Am J Ophthalmol. 144(5):769-775, 2007
                                            4. Prabhakaran VC et al: Orbital and adnexal sarcoidosis. Arch Ophthalmol. 125(12):1657-62, 2007
                                            5. Yamada R et al: Assessment of blood flow in orbital arteries in ocular sarcoidosis. Curr Eye Res. 24(3):219-23, 2002
                                            6. Simon EM et al: Systemic sarcoidosis with bilateral orbital involvement: MR findings. AJNR Am J Neuroradiol. 19(2):336-7, 1998
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Pathology

                                                    • Clinical Issues

                                                      • Diagnostic Checklist

                                                        TERMINOLOGY

                                                        • Definitions

                                                          • Noncaseating granulomatous inflammation of orbit
                                                          • Orbital sarcoid reaction = involvement limited to orbit without systemic disease

                                                        IMAGING

                                                        • General Features

                                                          • CT Findings

                                                            • MR Findings

                                                              • Ultrasonographic Findings

                                                                • Nuclear Medicine Findings

                                                                  • Imaging Recommendations

                                                                    DIFFERENTIAL DIAGNOSIS

                                                                      PATHOLOGY

                                                                      • General Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  DIAGNOSTIC CHECKLIST

                                                                                  • Consider

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Rosenbaum JT et al: Parallel gene expression changes in sarcoidosis involving the lacrimal gland, orbital tissue, or blood. JAMA Ophthalmol. 133(7):770-7, 2015
                                                                                      2. Demirci H et al: Orbital and adnexal involvement in sarcoidosis: analysis of clinical features and systemic disease in 30 cases. Am J Ophthalmol. 151(6):1074-1080, 2011
                                                                                      3. Mavrikakis I et al: Diverse clinical presentations of orbital sarcoid. Am J Ophthalmol. 144(5):769-775, 2007
                                                                                      4. Prabhakaran VC et al: Orbital and adnexal sarcoidosis. Arch Ophthalmol. 125(12):1657-62, 2007
                                                                                      5. Yamada R et al: Assessment of blood flow in orbital arteries in ocular sarcoidosis. Curr Eye Res. 24(3):219-23, 2002
                                                                                      6. Simon EM et al: Systemic sarcoidosis with bilateral orbital involvement: MR findings. AJNR Am J Neuroradiol. 19(2):336-7, 1998