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Organizing Pneumonia
Jorge Alberto Carrillo-Bayona, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Organizing pneumonia (OP)
                • Cicatricial organizing pneumonia (CiOP)
                • Cryptogenic organizing pneumonia (COP)
              • Synonyms

                • Bronchiolitis obliterans organizing pneumonia (BOOP): Term no longer in use
              • Definitions

                • OP: Pathological pattern defined by intraalveolar buds of granulation tissue consisting of fibroblasts and myofibroblasts intermixed with loose connective tissue matrix, especially consisting of collagen
                • OP is relatively common manifestation of acute lung injury
                • CiOP: Intraluminal collagen deposition on background of otherwise classic OP with formation of peculiar fibrous nodules or fibrotic linear bands
                • COP: Clinical pathological entity without known cause, histologically characterized by OP

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • Nuclear Medicine Findings

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      Selected References

                                      1. Lee JH et al: Diagnostic procedures and clinico-radiological findings of acute fibrinous and organizing pneumonia: a systematic review and pooled analysis. Eur Radiol. (10):7283-7294, 2021
                                      2. Zare Mehrjardi M et al: Radio-pathological correlation of organizing pneumonia (OP): a pictorial review. Br J Radiol. 90(1071):20160723, 2017
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Top Differential Diagnoses

                                            • Pathology

                                              • Clinical Issues

                                                • Diagnostic Checklist

                                                  TERMINOLOGY

                                                  • Abbreviations

                                                    • Organizing pneumonia (OP)
                                                    • Cicatricial organizing pneumonia (CiOP)
                                                    • Cryptogenic organizing pneumonia (COP)
                                                  • Synonyms

                                                    • Bronchiolitis obliterans organizing pneumonia (BOOP): Term no longer in use
                                                  • Definitions

                                                    • OP: Pathological pattern defined by intraalveolar buds of granulation tissue consisting of fibroblasts and myofibroblasts intermixed with loose connective tissue matrix, especially consisting of collagen
                                                    • OP is relatively common manifestation of acute lung injury
                                                    • CiOP: Intraluminal collagen deposition on background of otherwise classic OP with formation of peculiar fibrous nodules or fibrotic linear bands
                                                    • COP: Clinical pathological entity without known cause, histologically characterized by OP

                                                  IMAGING

                                                  • General Features

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • Nuclear Medicine Findings

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • General Features

                                                              • Gross Pathologic & Surgical Features

                                                                • Microscopic Features

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Natural History & Prognosis

                                                                      • Treatment

                                                                        DIAGNOSTIC CHECKLIST

                                                                        • Consider

                                                                          Selected References

                                                                          1. Lee JH et al: Diagnostic procedures and clinico-radiological findings of acute fibrinous and organizing pneumonia: a systematic review and pooled analysis. Eur Radiol. (10):7283-7294, 2021
                                                                          2. Zare Mehrjardi M et al: Radio-pathological correlation of organizing pneumonia (OP): a pictorial review. Br J Radiol. 90(1071):20160723, 2017