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Osteoarthritis of Wrist and Hand
Eva M. Escobedo, MD; B. J. Manaster, MD, PhD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Osteoarthritis (OA)
            • Synonyms

              • Degenerative joint disease (DJD), osteoarthrosis
              • Variant: erosive OA (EOA) a.k.a. inflammatory OA
            • Definitions

              • OA: noninflammatory arthritis due to progressive loss of cartilage
                • Resultant hypertrophic change in bone
              • EOA: inflammatory variant of OA

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Grunz JP et al: Osteoarthritis of the wrist: pathology, radiology, and treatment. Semin Musculoskelet Radiol. 25(2):294-303, 2021
                                          2. McAlindon TE et al: Erosive hand osteoarthritis: incidence and predictive characteristics among participants in the osteoarthritis initiative. Arthritis Rheumatol. 73(11):2015-24, 2021
                                          3. Pomares G: Trapeziometacarpal osteoarthritis and arthritis of the wrist. Hand Surg Rehabil. 40S:S135-42, 2021
                                          4. Tenti S et al: Impact of thumb osteoarthritis on pain, function, and quality of life: a comparative study between erosive and non-erosive hand osteoarthritis. Clin Rheumatol. 39(7):2195-206, 2020
                                          5. Perrotta FM et al: An assessment of hand erosive osteoarthritis: correlation of radiographic severity with clinical, functional and laboratory findings. Rheumatol Ther. 6(1):125-33, 2019
                                          6. van Beest S et al: In finger osteoarthritis, change in synovitis is associated with change in pain on a joint-level; a longitudinal magnetic resonance imaging study. Osteoarthritis Cartilage. 27(7):1048-56, 2019
                                          7. Sivakumaran P et al: Comparison between several ultrasound hand joint scores and conventional radiography in diagnosing hand osteoarthritis. Ultrasound Med Biol. 44(3):544-50, 2018
                                          8. Yuan F et al: Evidence-based practice in the surgical treatment of thumb carpometacarpal joint arthritis. J Hand Surg Am. 42(2):104-12.e1, 2017
                                          9. Haugen IK et al: Increasing synovitis and bone marrow lesions are associated with incident joint tenderness in hand osteoarthritis. Ann Rheum Dis. 75: 702-8, 2016
                                          10. Haugen IK et al: Synovitis and radiographic progression in non-erosive and erosive hand osteoarthritis: is erosive hand osteoarthritis a separate inflammatory phenotype? Osteoarthritis Cartilage. 24(4):647-54, 2016
                                          11. Mathiessen A et al: Ultrasound-detected inflammation predicts radiographic progression in hand osteoarthritis after 5years. Ann Rheum Dis. 75(5):825-30, 2016
                                          12. Berger AJ et al: Management of osteoarthrosis of the thumb joints. J Hand Surg Am. 40(4):843-50, 2015
                                          13. Melville DM et al: Imaging and management of thumb carpometacarpal joint osteoarthritis. Skeletal Radiol. 44(2):165-77, 2015
                                          14. Saltzherr MS et al: Computed tomography for the detection of thumb base osteoarthritis: comparison with digital radiography. Skeletal Radiol. 42(5):715-21, 2013
                                          15. Filková M et al: Increased serum adiponectin levels in female patients with erosive compared with non-erosive osteoarthritis. Ann Rheum Dis. 68(2):295-6, 2009
                                          16. Matsos M et al: Ultrasound of the hands and feet for rheumatological disorders: influence on clinical diagnostic confidence and patient management. Skeletal Radiol. 38(11):1049-54, 2009
                                          17. El-Sherif HE et al: Hand osteoarthritis and bone mineral density in postmenopausal women; clinical relevance to hand function, pain and disability. Osteoarthritis Cartilage. 16(1):12-7, 2008
                                          18. Grainger AJ et al: MR imaging of erosions in interphalangeal joint osteoarthritis: is all osteoarthritis erosive? Skeletal Radiol. 36(8):737-45, 2007
                                          19. Magnano MD et al: A pilot study of tumor necrosis factor inhibition in erosive/inflammatory osteoarthritis of the hands. J Rheumatol. 34(6):1323-7, 2007
                                          20. Mas AJ et al: Erosive osteoarthritis of the feet: description of two patients. Joint Bone Spine. 74(3):296-8, 2007
                                          21. Silvestri T et al: Elevated serum levels of soluble interleukin-4 receptor in osteoarthritis. Osteoarthritis Cartilage. 14(7):717-9, 2006
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Abbreviations

                                                      • Osteoarthritis (OA)
                                                    • Synonyms

                                                      • Degenerative joint disease (DJD), osteoarthrosis
                                                      • Variant: erosive OA (EOA) a.k.a. inflammatory OA
                                                    • Definitions

                                                      • OA: noninflammatory arthritis due to progressive loss of cartilage
                                                        • Resultant hypertrophic change in bone
                                                      • EOA: inflammatory variant of OA

                                                    IMAGING

                                                    • General Features

                                                      • Radiographic Findings

                                                        • CT Findings

                                                          • MR Findings

                                                            • Ultrasonographic Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Gross Pathologic & Surgical Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Grunz JP et al: Osteoarthritis of the wrist: pathology, radiology, and treatment. Semin Musculoskelet Radiol. 25(2):294-303, 2021
                                                                                  2. McAlindon TE et al: Erosive hand osteoarthritis: incidence and predictive characteristics among participants in the osteoarthritis initiative. Arthritis Rheumatol. 73(11):2015-24, 2021
                                                                                  3. Pomares G: Trapeziometacarpal osteoarthritis and arthritis of the wrist. Hand Surg Rehabil. 40S:S135-42, 2021
                                                                                  4. Tenti S et al: Impact of thumb osteoarthritis on pain, function, and quality of life: a comparative study between erosive and non-erosive hand osteoarthritis. Clin Rheumatol. 39(7):2195-206, 2020
                                                                                  5. Perrotta FM et al: An assessment of hand erosive osteoarthritis: correlation of radiographic severity with clinical, functional and laboratory findings. Rheumatol Ther. 6(1):125-33, 2019
                                                                                  6. van Beest S et al: In finger osteoarthritis, change in synovitis is associated with change in pain on a joint-level; a longitudinal magnetic resonance imaging study. Osteoarthritis Cartilage. 27(7):1048-56, 2019
                                                                                  7. Sivakumaran P et al: Comparison between several ultrasound hand joint scores and conventional radiography in diagnosing hand osteoarthritis. Ultrasound Med Biol. 44(3):544-50, 2018
                                                                                  8. Yuan F et al: Evidence-based practice in the surgical treatment of thumb carpometacarpal joint arthritis. J Hand Surg Am. 42(2):104-12.e1, 2017
                                                                                  9. Haugen IK et al: Increasing synovitis and bone marrow lesions are associated with incident joint tenderness in hand osteoarthritis. Ann Rheum Dis. 75: 702-8, 2016
                                                                                  10. Haugen IK et al: Synovitis and radiographic progression in non-erosive and erosive hand osteoarthritis: is erosive hand osteoarthritis a separate inflammatory phenotype? Osteoarthritis Cartilage. 24(4):647-54, 2016
                                                                                  11. Mathiessen A et al: Ultrasound-detected inflammation predicts radiographic progression in hand osteoarthritis after 5years. Ann Rheum Dis. 75(5):825-30, 2016
                                                                                  12. Berger AJ et al: Management of osteoarthrosis of the thumb joints. J Hand Surg Am. 40(4):843-50, 2015
                                                                                  13. Melville DM et al: Imaging and management of thumb carpometacarpal joint osteoarthritis. Skeletal Radiol. 44(2):165-77, 2015
                                                                                  14. Saltzherr MS et al: Computed tomography for the detection of thumb base osteoarthritis: comparison with digital radiography. Skeletal Radiol. 42(5):715-21, 2013
                                                                                  15. Filková M et al: Increased serum adiponectin levels in female patients with erosive compared with non-erosive osteoarthritis. Ann Rheum Dis. 68(2):295-6, 2009
                                                                                  16. Matsos M et al: Ultrasound of the hands and feet for rheumatological disorders: influence on clinical diagnostic confidence and patient management. Skeletal Radiol. 38(11):1049-54, 2009
                                                                                  17. El-Sherif HE et al: Hand osteoarthritis and bone mineral density in postmenopausal women; clinical relevance to hand function, pain and disability. Osteoarthritis Cartilage. 16(1):12-7, 2008
                                                                                  18. Grainger AJ et al: MR imaging of erosions in interphalangeal joint osteoarthritis: is all osteoarthritis erosive? Skeletal Radiol. 36(8):737-45, 2007
                                                                                  19. Magnano MD et al: A pilot study of tumor necrosis factor inhibition in erosive/inflammatory osteoarthritis of the hands. J Rheumatol. 34(6):1323-7, 2007
                                                                                  20. Mas AJ et al: Erosive osteoarthritis of the feet: description of two patients. Joint Bone Spine. 74(3):296-8, 2007
                                                                                  21. Silvestri T et al: Elevated serum levels of soluble interleukin-4 receptor in osteoarthritis. Osteoarthritis Cartilage. 14(7):717-9, 2006