Bookmarks
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Definitions
- Osteoblastoma (OB): Benign tumor that forms osteoid
- Differentiated grossly from osteoid osteoma by larger size (> 1.5 cm)
- Osteoblastoma (OB): Benign tumor that forms osteoid
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Angiographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Mishra A et al: Cervical spine osteoblastoma with an aneurysmal bone cyst in a 2-year-old child: a case report. Pediatr Neurosurg. 54(1):46-50, 2019
- Jia Q et al: Factors affecting prognosis of patients with osteoblastoma of the mobile spine: a long-term follow-up study of 70 patients in a single center. Neurosurgery. 86(1):71-9, 2018
- Galgano MA et al: Osteoblastomas of the spine: a comprehensive review. Neurosurg Focus. 41(2):E4, 2016
- Orguc S et al: Primary tumors of the spine. Semin Musculoskelet Radiol. 18(3):280-99, 2014
- Ruggieri P et al: Osteoblastoma of the sacrum: report of 18 cases and analysis of the literature. Spine (Phila Pa 1976). 39(2):E97-103, 2014
- Li Z et al: Clinical features and surgical management of spinal osteoblastoma: a retrospective study in 18 cases. PLoS One. 8(9):e74635, 2013
- Singh DK et al: Aggressive osteoblastoma involving the craniovertebral junction: a case report and review of literature. J Craniovertebr Junction Spine. 4(2):69-72, 2013
- Harrop JS et al: Aggressive "benign" primary spine neoplasms: osteoblastoma, aneurysmal bone cyst, and giant cell tumor. Spine (Phila Pa 1976). 34(22 Suppl):S39-47, 2009
- Qian BP et al: Spinal osteoblastoma complicated with epidural hematoma: two case reports. Spine (Phila Pa 1976). 34(12):E447-51, 2009
- Kan P et al: Osteoid osteoma and osteoblastoma of the spine. Neurosurg Clin N Am. 19(1):65-70, 2008
- Biagini R et al: Osteoid osteoma and osteoblastoma of the sacrum. Orthopedics. 24(11):1061-4, 2001
- Okuda S et al: Ossification of the ligamentum flavum associated with osteoblastoma: a report of three cases. Skeletal Radiol. 30(7):402-6, 2001
- Shaikh MI et al: Spinal osteoblastoma: CT and MR imaging with pathological correlation. Skeletal Radiol. 28(1):33-40, 1999
- Saifuddin A et al: Osteoid osteoma and osteoblastoma of the spine. Factors associated with the presence of scoliosis. Spine. 23(1):47-53, 1998
- Cheung FM et al: Diagnostic criteria for pseudomalignant osteoblastoma. Histopathology. 31(2):196-200, 1997
- Murphey MD et al: From the archives of the AFIP. Primary tumors of the spine: radiologic pathologic correlation. Radiographics. 16(5):1131-58, 1996
- Greenspan A: Benign bone-forming lesions: osteoma, osteoid osteoma, and osteoblastoma. Skeletal Radiol. 22(7):485-500, 1993
- Boriani S et al: Osteoblastoma of the spine. Clin Orthop Relat Res. (278):37-45, 1992
- Crim JR et al: Widespread inflammatory response to osteoblastoma: the flare phenomenon. Radiology. 177(3):835-6, 1990
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Definitions
- Osteoblastoma (OB): Benign tumor that forms osteoid
- Differentiated grossly from osteoid osteoma by larger size (> 1.5 cm)
- Osteoblastoma (OB): Benign tumor that forms osteoid
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Angiographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Mishra A et al: Cervical spine osteoblastoma with an aneurysmal bone cyst in a 2-year-old child: a case report. Pediatr Neurosurg. 54(1):46-50, 2019
- Jia Q et al: Factors affecting prognosis of patients with osteoblastoma of the mobile spine: a long-term follow-up study of 70 patients in a single center. Neurosurgery. 86(1):71-9, 2018
- Galgano MA et al: Osteoblastomas of the spine: a comprehensive review. Neurosurg Focus. 41(2):E4, 2016
- Orguc S et al: Primary tumors of the spine. Semin Musculoskelet Radiol. 18(3):280-99, 2014
- Ruggieri P et al: Osteoblastoma of the sacrum: report of 18 cases and analysis of the literature. Spine (Phila Pa 1976). 39(2):E97-103, 2014
- Li Z et al: Clinical features and surgical management of spinal osteoblastoma: a retrospective study in 18 cases. PLoS One. 8(9):e74635, 2013
- Singh DK et al: Aggressive osteoblastoma involving the craniovertebral junction: a case report and review of literature. J Craniovertebr Junction Spine. 4(2):69-72, 2013
- Harrop JS et al: Aggressive "benign" primary spine neoplasms: osteoblastoma, aneurysmal bone cyst, and giant cell tumor. Spine (Phila Pa 1976). 34(22 Suppl):S39-47, 2009
- Qian BP et al: Spinal osteoblastoma complicated with epidural hematoma: two case reports. Spine (Phila Pa 1976). 34(12):E447-51, 2009
- Kan P et al: Osteoid osteoma and osteoblastoma of the spine. Neurosurg Clin N Am. 19(1):65-70, 2008
- Biagini R et al: Osteoid osteoma and osteoblastoma of the sacrum. Orthopedics. 24(11):1061-4, 2001
- Okuda S et al: Ossification of the ligamentum flavum associated with osteoblastoma: a report of three cases. Skeletal Radiol. 30(7):402-6, 2001
- Shaikh MI et al: Spinal osteoblastoma: CT and MR imaging with pathological correlation. Skeletal Radiol. 28(1):33-40, 1999
- Saifuddin A et al: Osteoid osteoma and osteoblastoma of the spine. Factors associated with the presence of scoliosis. Spine. 23(1):47-53, 1998
- Cheung FM et al: Diagnostic criteria for pseudomalignant osteoblastoma. Histopathology. 31(2):196-200, 1997
- Murphey MD et al: From the archives of the AFIP. Primary tumors of the spine: radiologic pathologic correlation. Radiographics. 16(5):1131-58, 1996
- Greenspan A: Benign bone-forming lesions: osteoma, osteoid osteoma, and osteoblastoma. Skeletal Radiol. 22(7):485-500, 1993
- Boriani S et al: Osteoblastoma of the spine. Clin Orthop Relat Res. (278):37-45, 1992
- Crim JR et al: Widespread inflammatory response to osteoblastoma: the flare phenomenon. Radiology. 177(3):835-6, 1990
