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Osteochondroma, Spine
Bryson Borg, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Osteochondroma (OC)
                • Hereditary multiple exostoses (HME)
              • Synonyms

                • Osteocartilaginous exostosis, exostosis
                • HME, a.k.a. diaphyseal aclasis, multiple cartilaginous exostoses
              • Definitions

                • Cartilage-capped osseous excrescence contiguous with parent bone

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Ultrasonographic Findings

                        • Nuclear Medicine Findings

                          • Imaging Recommendations

                            DIFFERENTIAL DIAGNOSIS

                              PATHOLOGY

                              • General Features

                                • Gross Pathologic & Surgical Features

                                  • Microscopic Features

                                    CLINICAL ISSUES

                                    • Presentation

                                      • Demographics

                                        • Natural History & Prognosis

                                          • Treatment

                                            DIAGNOSTIC CHECKLIST

                                            • Consider

                                              • Image Interpretation Pearls

                                                Selected References

                                                1. Kuraishi K et al: Symptomatic osteochondroma of lumbosacral spine: report of 5 cases. Neurol Med Chir (Tokyo). 54(5):408-12, 2014
                                                2. Ogul H et al: An unusual cause of spinal compression in a young woman: cervical osteochondroma. Spine J. Epub ahead of print, 2014
                                                3. Sadek AR et al: Multiple spinal osteochondromata and osteosarcoma in a patient with Gorlin's syndrome. Clin Neurol Neurosurg. 118:5-8, 2014
                                                4. Altaf F et al: Osteochondroma of C1 causing vertebral artery occlusion. Br J Neurosurg. 27(1):130-1, 2013
                                                5. Lee JY et al: Subclinical cervical osteochondroma presenting as brown-sequard syndrome after trivial neck trauma. J Korean Neurosurg Soc. 51(4):233-6, 2012
                                                6. Mudumba V et al: Cervical osteochondroma presenting with acute quadriplegia. Asian J Neurosurg. 7(2):101-2, 2012
                                                7. Tian Y et al: Spinal cord compression secondary to a thoracic vertebral osteochondroma. J Neurosurg Spine. 15(3):252-7, 2011
                                                8. Aldea S et al: Acute spinal cord compression in hereditary multiple exostoses. Acta Neurochir (Wien). 148(2):195-8; discussion 198, 2006
                                                9. Moon KS et al: Osteochondroma of the cervical spine extending multiple segments with cord compression. Pediatr Neurosurg. 42(5):304-7, 2006
                                                10. Kouwenhoven JW et al: Headache due to an osteochondroma of the axis. Eur Spine J. 13(8):746-9, 2004
                                                11. Taitz J et al: Osteochondroma after total body irradiation: an age-related complication. Pediatr Blood Cancer. 42(3):225-9, 2004
                                                12. Akagi S et al: Osteochondroma of the upper cervical spine presenting as vertigo. Orthopedics. 26(2):187-8, 2003
                                                13. Pierz KA et al: Hereditary multiple exostoses: one center's experience and review of etiology. Clin Orthop. (401):49-59, 2002
                                                14. Ratliff J et al: Osteochondroma of the C5 lamina with cord compression: case report and review of the literature. Spine. 25(10):1293-5, 2000
                                                15. Silber JS et al: A solitary osteochondroma of the pediatric thoracic spine: a case report and review of the literature. Am J Orthop. 29(9):711-4, 2000
                                                16. Wuyts W et al: Molecular basis of multiple exostoses: mutations in the EXT1 and EXT2 genes. Hum Mutat. 15(3):220-7, 2000
                                                Related Anatomy
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                                                Related Differential Diagnoses
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                                                References
                                                Tables

                                                Tables

                                                KEY FACTS

                                                • Terminology

                                                  • Imaging

                                                    • Top Differential Diagnoses

                                                      • Pathology

                                                        • Clinical Issues

                                                          • Diagnostic Checklist

                                                            TERMINOLOGY

                                                            • Abbreviations

                                                              • Osteochondroma (OC)
                                                              • Hereditary multiple exostoses (HME)
                                                            • Synonyms

                                                              • Osteocartilaginous exostosis, exostosis
                                                              • HME, a.k.a. diaphyseal aclasis, multiple cartilaginous exostoses
                                                            • Definitions

                                                              • Cartilage-capped osseous excrescence contiguous with parent bone

                                                            IMAGING

                                                            • General Features

                                                              • Radiographic Findings

                                                                • CT Findings

                                                                  • MR Findings

                                                                    • Ultrasonographic Findings

                                                                      • Nuclear Medicine Findings

                                                                        • Imaging Recommendations

                                                                          DIFFERENTIAL DIAGNOSIS

                                                                            PATHOLOGY

                                                                            • General Features

                                                                              • Gross Pathologic & Surgical Features

                                                                                • Microscopic Features

                                                                                  CLINICAL ISSUES

                                                                                  • Presentation

                                                                                    • Demographics

                                                                                      • Natural History & Prognosis

                                                                                        • Treatment

                                                                                          DIAGNOSTIC CHECKLIST

                                                                                          • Consider

                                                                                            • Image Interpretation Pearls

                                                                                              Selected References

                                                                                              1. Kuraishi K et al: Symptomatic osteochondroma of lumbosacral spine: report of 5 cases. Neurol Med Chir (Tokyo). 54(5):408-12, 2014
                                                                                              2. Ogul H et al: An unusual cause of spinal compression in a young woman: cervical osteochondroma. Spine J. Epub ahead of print, 2014
                                                                                              3. Sadek AR et al: Multiple spinal osteochondromata and osteosarcoma in a patient with Gorlin's syndrome. Clin Neurol Neurosurg. 118:5-8, 2014
                                                                                              4. Altaf F et al: Osteochondroma of C1 causing vertebral artery occlusion. Br J Neurosurg. 27(1):130-1, 2013
                                                                                              5. Lee JY et al: Subclinical cervical osteochondroma presenting as brown-sequard syndrome after trivial neck trauma. J Korean Neurosurg Soc. 51(4):233-6, 2012
                                                                                              6. Mudumba V et al: Cervical osteochondroma presenting with acute quadriplegia. Asian J Neurosurg. 7(2):101-2, 2012
                                                                                              7. Tian Y et al: Spinal cord compression secondary to a thoracic vertebral osteochondroma. J Neurosurg Spine. 15(3):252-7, 2011
                                                                                              8. Aldea S et al: Acute spinal cord compression in hereditary multiple exostoses. Acta Neurochir (Wien). 148(2):195-8; discussion 198, 2006
                                                                                              9. Moon KS et al: Osteochondroma of the cervical spine extending multiple segments with cord compression. Pediatr Neurosurg. 42(5):304-7, 2006
                                                                                              10. Kouwenhoven JW et al: Headache due to an osteochondroma of the axis. Eur Spine J. 13(8):746-9, 2004
                                                                                              11. Taitz J et al: Osteochondroma after total body irradiation: an age-related complication. Pediatr Blood Cancer. 42(3):225-9, 2004
                                                                                              12. Akagi S et al: Osteochondroma of the upper cervical spine presenting as vertigo. Orthopedics. 26(2):187-8, 2003
                                                                                              13. Pierz KA et al: Hereditary multiple exostoses: one center's experience and review of etiology. Clin Orthop. (401):49-59, 2002
                                                                                              14. Ratliff J et al: Osteochondroma of the C5 lamina with cord compression: case report and review of the literature. Spine. 25(10):1293-5, 2000
                                                                                              15. Silber JS et al: A solitary osteochondroma of the pediatric thoracic spine: a case report and review of the literature. Am J Orthop. 29(9):711-4, 2000
                                                                                              16. Wuyts W et al: Molecular basis of multiple exostoses: mutations in the EXT1 and EXT2 genes. Hum Mutat. 15(3):220-7, 2000