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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Osteofibrous dysplasia (OFD)
Synonyms
- Not recommended: ossifying fibroma of long bones, Kempson-Campanacci lesion
Definitions
- Benign fibroosseous tumor of childhood that typically arises in anterior cortex of tibia ± fibula
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Image-Guided Biopsy
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Reporting Tips
Selected References
- Kamal AF et al: Osteofibrous dysplasia-like adamantinoma versus osteofibrous dysplasia in children: a case report of challenging diagnosis. Int J Surg Case Rep. 80:105599, 2021
- Deng Z et al: Outcome of osteofibrous dysplasia-like versus classic adamantinoma of long bones: a single-institution experience. J Orthop Surg Res. 15(1):268, 2020
- Nielsen N et al: Osteofibrous dysplasia. In Fletcher CDM et al: WHO Classification of Tumours: Tumours of Soft Tissue and Bone. IARC Press. 460-2, 2020
- Westacott D et al: Osteofibrous dysplasia of the tibia in children: outcome without resection. J Pediatr Orthop. 39(8):e614-21, 2019
- Ondhia M et al: Paediatric osteofibrous dysplasia-like adamantinoma with classical radiological findings. BMJ Case Rep. 2018, 2018
- Bethapudi S et al: Imaging in osteofibrous dysplasia, osteofibrous dysplasia-like adamantinoma, and classic adamantinoma. Clin Radiol. 69(2):200-8, 2014
- Jung JY et al: MR findings of the osteofibrous dysplasia. Korean J Radiol. 15(1):114-22, 2014
- Most MJ et al: Osteofibrous dysplasia and adamantinoma. J Am Acad Orthop Surg. 18(6):358-66, 2010
- Gleason BC et al: Osteofibrous dysplasia and adamantinoma in children and adolescents: a clinicopathologic reappraisal. Am J Surg Pathol. 32(3):363-76, 2008
- Khanna M et al: Osteofibrous dysplasia, osteofibrous dysplasia-like adamantinoma and adamantinoma: correlation of radiological imaging features with surgical histology and assessment of the use of radiology in contributing to needle biopsy diagnosis. Skeletal Radiol. 37(12):1077-84, 2008
- Lee RS et al: Osteofibrous dysplasia of the tibia. Is there a need for a radical surgical approach? J Bone Joint Surg Br. 88(5):658-64, 2006
- Van der Woude HJ et al: MRI of adamantinoma of long bones in correlation with histopathology. AJR Am J Roentgenol. 183(6):1737-44, 2004
- Nakashima Y et al: Osteofibrous dysplasia (ossifying fibroma of long bones). A study of 12 cases. Cancer. 52(5):909-14, 1983
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Osteofibrous dysplasia (OFD)
Synonyms
- Not recommended: ossifying fibroma of long bones, Kempson-Campanacci lesion
Definitions
- Benign fibroosseous tumor of childhood that typically arises in anterior cortex of tibia ± fibula
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Image-Guided Biopsy
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Reporting Tips
Selected References
- Kamal AF et al: Osteofibrous dysplasia-like adamantinoma versus osteofibrous dysplasia in children: a case report of challenging diagnosis. Int J Surg Case Rep. 80:105599, 2021
- Deng Z et al: Outcome of osteofibrous dysplasia-like versus classic adamantinoma of long bones: a single-institution experience. J Orthop Surg Res. 15(1):268, 2020
- Nielsen N et al: Osteofibrous dysplasia. In Fletcher CDM et al: WHO Classification of Tumours: Tumours of Soft Tissue and Bone. IARC Press. 460-2, 2020
- Westacott D et al: Osteofibrous dysplasia of the tibia in children: outcome without resection. J Pediatr Orthop. 39(8):e614-21, 2019
- Ondhia M et al: Paediatric osteofibrous dysplasia-like adamantinoma with classical radiological findings. BMJ Case Rep. 2018, 2018
- Bethapudi S et al: Imaging in osteofibrous dysplasia, osteofibrous dysplasia-like adamantinoma, and classic adamantinoma. Clin Radiol. 69(2):200-8, 2014
- Jung JY et al: MR findings of the osteofibrous dysplasia. Korean J Radiol. 15(1):114-22, 2014
- Most MJ et al: Osteofibrous dysplasia and adamantinoma. J Am Acad Orthop Surg. 18(6):358-66, 2010
- Gleason BC et al: Osteofibrous dysplasia and adamantinoma in children and adolescents: a clinicopathologic reappraisal. Am J Surg Pathol. 32(3):363-76, 2008
- Khanna M et al: Osteofibrous dysplasia, osteofibrous dysplasia-like adamantinoma and adamantinoma: correlation of radiological imaging features with surgical histology and assessment of the use of radiology in contributing to needle biopsy diagnosis. Skeletal Radiol. 37(12):1077-84, 2008
- Lee RS et al: Osteofibrous dysplasia of the tibia. Is there a need for a radical surgical approach? J Bone Joint Surg Br. 88(5):658-64, 2006
- Van der Woude HJ et al: MRI of adamantinoma of long bones in correlation with histopathology. AJR Am J Roentgenol. 183(6):1737-44, 2004
- Nakashima Y et al: Osteofibrous dysplasia (ossifying fibroma of long bones). A study of 12 cases. Cancer. 52(5):909-14, 1983
