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Osteoid Osteoma, Spine
Julia R. Crim, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Osteoid osteoma (OO)
              • Definitions

                • Benign osteoid-producing tumor < 1.5 cm in size
                • Tumor often called "nidus" to distinguish it from surrounding reactive zone due to host response

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Nuclear Medicine Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              Selected References

                                              1. Cappuccio M et al: Cervical osteoid osteoma progression to osteoblastoma. Spine J. 14(6):1070-1, 2014
                                              2. Amendola L et al: Multicentric osteoid osteoma in C5 vertebra and parietal bone. Spine J. 13(12):1960-1, 2013
                                              3. Even JL et al: Osteoid osteoma of the lumbar spine. Spine J. 12(10):971-2, 2012
                                              4. Kan P et al: Osteoid osteoma and osteoblastoma of the spine. Neurosurg Clin N Am. 19(1):65-70, 2008
                                              5. Liu PT et al: Imaging of osteoid osteoma with dynamic gadolinium-enhanced MR imaging. Radiology. 227(3):691-700, 2003
                                              6. Davies M et al: The diagnostic accuracy of MR imaging in osteoid osteoma. Skeletal Radiol. 31(10):559-69, 2002
                                              7. Scuotto A et al: Unusual manifestation of vertebral osteoid osteoma: case report. Eur Radiol. 12(1):109-12, 2002
                                              8. Lefton DR et al: Vertebral osteoid osteoma masquerading as a malignant bone or soft-tissue tumor on MRI. Pediatr Radiol. 31(2):72-5, 2001
                                              9. Cove JA et al: Osteoid osteoma of the spine treated with percutaneous computed tomography-guided thermocoagulation. Spine. 25(10):1283-6, 2000
                                              10. Gangi A et al: Percutaneous laser photocoagulation of spinal osteoid osteomas under CT guidance. AJNR Am J Neuroradiol. 19(10):1955-8, 1998
                                              11. Radcliffe SN et al: Osteoid osteoma: the difficult diagnosis. Eur J Radiol. 28(1):67-79, 1998
                                              12. Assoun J et al: Osteoid osteoma: MR imaging versus CT. Radiology. 191(1):217-23, 1994
                                              13. Zambelli PY et al: Osteoid osteoma or osteoblastoma of the cervical spine in relation to the vertebral artery. J Pediatr Orthop. 14(6):788-92, 1994
                                              14. Greenspan A: Benign bone-forming lesions: osteoma, osteoid osteoma, and osteoblastoma. Clinical, imaging, pathologic, and differential considerations. Skeletal Radiol. 22(7):485-500, 1993
                                              15. Woods ER et al: Reactive soft-tissue mass associated with osteoid osteoma: correlation of MR imaging features with pathologic findings. Radiology. 186(1):221-5, 1993
                                              16. Klein MH et al: Osteoid osteoma: radiologic and pathologic correlation. Skeletal Radiol. 21(1):23-31, 1992
                                              17. Raskas DS et al: Osteoid osteoma and osteoblastoma of the spine. J Spinal Disord. 5(2): 204-11, 1992
                                              18. Afshani E et al: Common causes of low back pain in children. Radiographics. 11(2): 269-91, 1991
                                              19. Kransdorf MJ et al: Osteoid osteoma. Radiographics. 11(4):671-96, 1991
                                              20. Crim JR et al: Widespread inflammatory response to osteoblastoma: the flare phenomenon. Radiology. 177(3):835-6, 1990
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Pathology

                                                      • Clinical Issues

                                                        • Diagnostic Checklist

                                                          TERMINOLOGY

                                                          • Abbreviations

                                                            • Osteoid osteoma (OO)
                                                          • Definitions

                                                            • Benign osteoid-producing tumor < 1.5 cm in size
                                                            • Tumor often called "nidus" to distinguish it from surrounding reactive zone due to host response

                                                          IMAGING

                                                          • General Features

                                                            • Radiographic Findings

                                                              • CT Findings

                                                                • MR Findings

                                                                  • Nuclear Medicine Findings

                                                                    • Imaging Recommendations

                                                                      DIFFERENTIAL DIAGNOSIS

                                                                        PATHOLOGY

                                                                        • General Features

                                                                          • Gross Pathologic & Surgical Features

                                                                            • Microscopic Features

                                                                              CLINICAL ISSUES

                                                                              • Presentation

                                                                                • Demographics

                                                                                  • Natural History & Prognosis

                                                                                    • Treatment

                                                                                      DIAGNOSTIC CHECKLIST

                                                                                      • Consider

                                                                                        • Image Interpretation Pearls

                                                                                          Selected References

                                                                                          1. Cappuccio M et al: Cervical osteoid osteoma progression to osteoblastoma. Spine J. 14(6):1070-1, 2014
                                                                                          2. Amendola L et al: Multicentric osteoid osteoma in C5 vertebra and parietal bone. Spine J. 13(12):1960-1, 2013
                                                                                          3. Even JL et al: Osteoid osteoma of the lumbar spine. Spine J. 12(10):971-2, 2012
                                                                                          4. Kan P et al: Osteoid osteoma and osteoblastoma of the spine. Neurosurg Clin N Am. 19(1):65-70, 2008
                                                                                          5. Liu PT et al: Imaging of osteoid osteoma with dynamic gadolinium-enhanced MR imaging. Radiology. 227(3):691-700, 2003
                                                                                          6. Davies M et al: The diagnostic accuracy of MR imaging in osteoid osteoma. Skeletal Radiol. 31(10):559-69, 2002
                                                                                          7. Scuotto A et al: Unusual manifestation of vertebral osteoid osteoma: case report. Eur Radiol. 12(1):109-12, 2002
                                                                                          8. Lefton DR et al: Vertebral osteoid osteoma masquerading as a malignant bone or soft-tissue tumor on MRI. Pediatr Radiol. 31(2):72-5, 2001
                                                                                          9. Cove JA et al: Osteoid osteoma of the spine treated with percutaneous computed tomography-guided thermocoagulation. Spine. 25(10):1283-6, 2000
                                                                                          10. Gangi A et al: Percutaneous laser photocoagulation of spinal osteoid osteomas under CT guidance. AJNR Am J Neuroradiol. 19(10):1955-8, 1998
                                                                                          11. Radcliffe SN et al: Osteoid osteoma: the difficult diagnosis. Eur J Radiol. 28(1):67-79, 1998
                                                                                          12. Assoun J et al: Osteoid osteoma: MR imaging versus CT. Radiology. 191(1):217-23, 1994
                                                                                          13. Zambelli PY et al: Osteoid osteoma or osteoblastoma of the cervical spine in relation to the vertebral artery. J Pediatr Orthop. 14(6):788-92, 1994
                                                                                          14. Greenspan A: Benign bone-forming lesions: osteoma, osteoid osteoma, and osteoblastoma. Clinical, imaging, pathologic, and differential considerations. Skeletal Radiol. 22(7):485-500, 1993
                                                                                          15. Woods ER et al: Reactive soft-tissue mass associated with osteoid osteoma: correlation of MR imaging features with pathologic findings. Radiology. 186(1):221-5, 1993
                                                                                          16. Klein MH et al: Osteoid osteoma: radiologic and pathologic correlation. Skeletal Radiol. 21(1):23-31, 1992
                                                                                          17. Raskas DS et al: Osteoid osteoma and osteoblastoma of the spine. J Spinal Disord. 5(2): 204-11, 1992
                                                                                          18. Afshani E et al: Common causes of low back pain in children. Radiographics. 11(2): 269-91, 1991
                                                                                          19. Kransdorf MJ et al: Osteoid osteoma. Radiographics. 11(4):671-96, 1991
                                                                                          20. Crim JR et al: Widespread inflammatory response to osteoblastoma: the flare phenomenon. Radiology. 177(3):835-6, 1990