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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Osteoid osteoma (OO)
Definitions
- Benign osteoid-producing tumor < 1.5 cm in size
- Tumor often called "nidus" to distinguish it from surrounding reactive zone due to host response
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Ono T et al: Osteoid osteoma can occur at the pars interarticularis of the lumbar spine, leading to misdiagnosis of lumbar spondylolysis. Am J Case Rep. 19:207-13, 2018
- Tomasian A et al: Spinal osteoid osteoma: percutaneous radiofrequency ablation using a navigational bipolar electrode system. AJR Am J Roentgenol. 211(4):856-60, 2018
- Tomasian A et al: Benign spine lesions: advances in techniques for minimally invasive percutaneous treatment. AJNR Am J Neuroradiol. 38(5):852-61, 2017
- Earhart J et al: Radiofrequency ablation in the treatment of osteoid osteoma: results and complications. Pediatr Radiol. 43(7):814-9, 2013
- Liu PT et al: The vascular groove sign: a new CT finding associated with osteoid osteomas. AJR Am J Roentgenol. 196(1):168-73, 2011
- Chai JW et al: Radiologic diagnosis of osteoid osteoma: from simple to challenging findings. Radiographics. 2010 May;30(3):737-49. Erratum in: Radiographics. 30(4):1156, 2010
- Hoffmann RT et al: Radiofrequency ablation in the treatment of osteoid osteoma-5-year experience. Eur J Radiol. 73(2):374-9, 2010
- Kan P et al: Osteoid osteoma and osteoblastoma of the spine. Neurosurg Clin N Am. 19(1):65-70, 2008
- Liu PT et al: Imaging of osteoid osteoma with dynamic gadolinium-enhanced MR imaging. Radiology. 227(3):691-700, 2003
- Davies M et al: The diagnostic accuracy of MR imaging in osteoid osteoma. Skeletal Radiol. 31(10):559-69, 2002
- Scuotto A et al: Unusual manifestation of vertebral osteoid osteoma: case report. Eur Radiol. 12(1):109-12, 2002
- Lefton DR et al: Vertebral osteoid osteoma masquerading as a malignant bone or soft-tissue tumor on MRI. Pediatr Radiol. 31(2):72-5, 2001
- Cove JA et al: Osteoid osteoma of the spine treated with percutaneous computed tomography-guided thermocoagulation. Spine. 25(10):1283-6, 2000
- Gangi A et al: Percutaneous laser photocoagulation of spinal osteoid osteomas under CT guidance. AJNR Am J Neuroradiol. 19(10):1955-8, 1998
- Radcliffe SN et al: Osteoid osteoma: the difficult diagnosis. Eur J Radiol. 28(1):67-79, 1998
- Assoun J et al: Osteoid osteoma: MR imaging versus CT. Radiology. 191(1):217-23, 1994
- Zambelli PY et al: Osteoid osteoma or osteoblastoma of the cervical spine in relation to the vertebral artery. J Pediatr Orthop. 14(6):788-92, 1994
- Greenspan A: Benign bone-forming lesions: osteoma, osteoid osteoma, and osteoblastoma. Clinical, imaging, pathologic, and differential considerations. Skeletal Radiol. 22(7):485-500, 1993
- Woods ER et al: Reactive soft-tissue mass associated with osteoid osteoma: correlation of MR imaging features with pathologic findings. Radiology. 186(1):221-5, 1993
- Klein MH et al: Osteoid osteoma: radiologic and pathologic correlation. Skeletal Radiol. 21(1):23-31, 1992
- Raskas DS et al: Osteoid osteoma and osteoblastoma of the spine. J Spinal Disord. 5(2): 204-11, 1992
- Afshani E et al: Common causes of low back pain in children. Radiographics. 11(2): 269-91, 1991
- Kransdorf MJ et al: Osteoid osteoma. Radiographics. 11(4):671-96, 1991
- Crim JR et al: Widespread inflammatory response to osteoblastoma: the flare phenomenon. Radiology. 177(3):835-6, 1990
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References
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Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Osteoid osteoma (OO)
Definitions
- Benign osteoid-producing tumor < 1.5 cm in size
- Tumor often called "nidus" to distinguish it from surrounding reactive zone due to host response
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Ono T et al: Osteoid osteoma can occur at the pars interarticularis of the lumbar spine, leading to misdiagnosis of lumbar spondylolysis. Am J Case Rep. 19:207-13, 2018
- Tomasian A et al: Spinal osteoid osteoma: percutaneous radiofrequency ablation using a navigational bipolar electrode system. AJR Am J Roentgenol. 211(4):856-60, 2018
- Tomasian A et al: Benign spine lesions: advances in techniques for minimally invasive percutaneous treatment. AJNR Am J Neuroradiol. 38(5):852-61, 2017
- Earhart J et al: Radiofrequency ablation in the treatment of osteoid osteoma: results and complications. Pediatr Radiol. 43(7):814-9, 2013
- Liu PT et al: The vascular groove sign: a new CT finding associated with osteoid osteomas. AJR Am J Roentgenol. 196(1):168-73, 2011
- Chai JW et al: Radiologic diagnosis of osteoid osteoma: from simple to challenging findings. Radiographics. 2010 May;30(3):737-49. Erratum in: Radiographics. 30(4):1156, 2010
- Hoffmann RT et al: Radiofrequency ablation in the treatment of osteoid osteoma-5-year experience. Eur J Radiol. 73(2):374-9, 2010
- Kan P et al: Osteoid osteoma and osteoblastoma of the spine. Neurosurg Clin N Am. 19(1):65-70, 2008
- Liu PT et al: Imaging of osteoid osteoma with dynamic gadolinium-enhanced MR imaging. Radiology. 227(3):691-700, 2003
- Davies M et al: The diagnostic accuracy of MR imaging in osteoid osteoma. Skeletal Radiol. 31(10):559-69, 2002
- Scuotto A et al: Unusual manifestation of vertebral osteoid osteoma: case report. Eur Radiol. 12(1):109-12, 2002
- Lefton DR et al: Vertebral osteoid osteoma masquerading as a malignant bone or soft-tissue tumor on MRI. Pediatr Radiol. 31(2):72-5, 2001
- Cove JA et al: Osteoid osteoma of the spine treated with percutaneous computed tomography-guided thermocoagulation. Spine. 25(10):1283-6, 2000
- Gangi A et al: Percutaneous laser photocoagulation of spinal osteoid osteomas under CT guidance. AJNR Am J Neuroradiol. 19(10):1955-8, 1998
- Radcliffe SN et al: Osteoid osteoma: the difficult diagnosis. Eur J Radiol. 28(1):67-79, 1998
- Assoun J et al: Osteoid osteoma: MR imaging versus CT. Radiology. 191(1):217-23, 1994
- Zambelli PY et al: Osteoid osteoma or osteoblastoma of the cervical spine in relation to the vertebral artery. J Pediatr Orthop. 14(6):788-92, 1994
- Greenspan A: Benign bone-forming lesions: osteoma, osteoid osteoma, and osteoblastoma. Clinical, imaging, pathologic, and differential considerations. Skeletal Radiol. 22(7):485-500, 1993
- Woods ER et al: Reactive soft-tissue mass associated with osteoid osteoma: correlation of MR imaging features with pathologic findings. Radiology. 186(1):221-5, 1993
- Klein MH et al: Osteoid osteoma: radiologic and pathologic correlation. Skeletal Radiol. 21(1):23-31, 1992
- Raskas DS et al: Osteoid osteoma and osteoblastoma of the spine. J Spinal Disord. 5(2): 204-11, 1992
- Afshani E et al: Common causes of low back pain in children. Radiographics. 11(2): 269-91, 1991
- Kransdorf MJ et al: Osteoid osteoma. Radiographics. 11(4):671-96, 1991
- Crim JR et al: Widespread inflammatory response to osteoblastoma: the flare phenomenon. Radiology. 177(3):835-6, 1990
