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Osteoid Osteoma
Kevin R. Moore, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Osteoid osteoma (OO)
            • Definitions

              • Benign osteoid-producing tumor < 1.5 cm in size
              • Tumor often called "nidus" to distinguish it from surrounding reactive zone due to host response

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Earhart J et al: Radiofrequency ablation in the treatment of osteoid osteoma: results and complications. Pediatr Radiol. 43(7):814-9, 2013
                                            2. Liu PT et al: The vascular groove sign: a new CT finding associated with osteoid osteomas. AJR Am J Roentgenol. 196(1):168-73, 2011
                                            3. Chai JW et al: Radiologic diagnosis of osteoid osteoma: from simple to challenging findings. Radiographics. 2010 May;30(3):737-49. Erratum in: Radiographics. 30(4):1156, 2010
                                            4. Hoffmann RT et al: Radiofrequency ablation in the treatment of osteoid osteoma-5-year experience. Eur J Radiol. 73(2):374-9, 2010
                                            5. Kan P et al: Osteoid osteoma and osteoblastoma of the spine. Neurosurg Clin N Am. 19(1):65-70, 2008
                                            6. Liu PT et al: Imaging of osteoid osteoma with dynamic gadolinium-enhanced MR imaging. Radiology. 227(3):691-700, 2003
                                            7. Davies M et al: The diagnostic accuracy of MR imaging in osteoid osteoma. Skeletal Radiol. 31(10):559-69, 2002
                                            8. Scuotto A et al: Unusual manifestation of vertebral osteoid osteoma: case report. Eur Radiol. 12(1):109-12, 2002
                                            9. Lefton DR et al: Vertebral osteoid osteoma masquerading as a malignant bone or soft-tissue tumor on MRI. Pediatr Radiol. 31(2):72-5, 2001
                                            10. Cove JA et al: Osteoid osteoma of the spine treated with percutaneous computed tomography-guided thermocoagulation. Spine. 25(10):1283-6, 2000
                                            11. Gangi A et al: Percutaneous laser photocoagulation of spinal osteoid osteomas under CT guidance. AJNR Am J Neuroradiol. 19(10):1955-8, 1998
                                            12. Radcliffe SN et al: Osteoid osteoma: the difficult diagnosis. Eur J Radiol. 28(1):67-79, 1998
                                            13. Assoun J et al: Osteoid osteoma: MR imaging versus CT. Radiology. 191(1):217-23, 1994
                                            14. Zambelli PY et al: Osteoid osteoma or osteoblastoma of the cervical spine in relation to the vertebral artery. J Pediatr Orthop. 14(6):788-92, 1994
                                            15. Greenspan A: Benign bone-forming lesions: osteoma, osteoid osteoma, and osteoblastoma. Clinical, imaging, pathologic, and differential considerations. Skeletal Radiol. 22(7):485-500, 1993
                                            16. Woods ER et al: Reactive soft-tissue mass associated with osteoid osteoma: correlation of MR imaging features with pathologic findings. Radiology. 186(1):221-5, 1993
                                            17. Klein MH et al: Osteoid osteoma: radiologic and pathologic correlation. Skeletal Radiol. 21(1):23-31, 1992
                                            18. Raskas DS et al: Osteoid osteoma and osteoblastoma of the spine. J Spinal Disord. 5(2): 204-11, 1992
                                            19. Afshani E et al: Common causes of low back pain in children. Radiographics. 11(2): 269-91, 1991
                                            20. Kransdorf MJ et al: Osteoid osteoma. Radiographics. 11(4):671-96, 1991
                                            21. Crim JR et al: Widespread inflammatory response to osteoblastoma: the flare phenomenon. Radiology. 177(3):835-6, 1990
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Abbreviations

                                                        • Osteoid osteoma (OO)
                                                      • Definitions

                                                        • Benign osteoid-producing tumor < 1.5 cm in size
                                                        • Tumor often called "nidus" to distinguish it from surrounding reactive zone due to host response

                                                      IMAGING

                                                      • General Features

                                                        • Radiographic Findings

                                                          • CT Findings

                                                            • MR Findings

                                                              • Nuclear Medicine Findings

                                                                • Imaging Recommendations

                                                                  DIFFERENTIAL DIAGNOSIS

                                                                    PATHOLOGY

                                                                    • General Features

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  DIAGNOSTIC CHECKLIST

                                                                                  • Consider

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Earhart J et al: Radiofrequency ablation in the treatment of osteoid osteoma: results and complications. Pediatr Radiol. 43(7):814-9, 2013
                                                                                      2. Liu PT et al: The vascular groove sign: a new CT finding associated with osteoid osteomas. AJR Am J Roentgenol. 196(1):168-73, 2011
                                                                                      3. Chai JW et al: Radiologic diagnosis of osteoid osteoma: from simple to challenging findings. Radiographics. 2010 May;30(3):737-49. Erratum in: Radiographics. 30(4):1156, 2010
                                                                                      4. Hoffmann RT et al: Radiofrequency ablation in the treatment of osteoid osteoma-5-year experience. Eur J Radiol. 73(2):374-9, 2010
                                                                                      5. Kan P et al: Osteoid osteoma and osteoblastoma of the spine. Neurosurg Clin N Am. 19(1):65-70, 2008
                                                                                      6. Liu PT et al: Imaging of osteoid osteoma with dynamic gadolinium-enhanced MR imaging. Radiology. 227(3):691-700, 2003
                                                                                      7. Davies M et al: The diagnostic accuracy of MR imaging in osteoid osteoma. Skeletal Radiol. 31(10):559-69, 2002
                                                                                      8. Scuotto A et al: Unusual manifestation of vertebral osteoid osteoma: case report. Eur Radiol. 12(1):109-12, 2002
                                                                                      9. Lefton DR et al: Vertebral osteoid osteoma masquerading as a malignant bone or soft-tissue tumor on MRI. Pediatr Radiol. 31(2):72-5, 2001
                                                                                      10. Cove JA et al: Osteoid osteoma of the spine treated with percutaneous computed tomography-guided thermocoagulation. Spine. 25(10):1283-6, 2000
                                                                                      11. Gangi A et al: Percutaneous laser photocoagulation of spinal osteoid osteomas under CT guidance. AJNR Am J Neuroradiol. 19(10):1955-8, 1998
                                                                                      12. Radcliffe SN et al: Osteoid osteoma: the difficult diagnosis. Eur J Radiol. 28(1):67-79, 1998
                                                                                      13. Assoun J et al: Osteoid osteoma: MR imaging versus CT. Radiology. 191(1):217-23, 1994
                                                                                      14. Zambelli PY et al: Osteoid osteoma or osteoblastoma of the cervical spine in relation to the vertebral artery. J Pediatr Orthop. 14(6):788-92, 1994
                                                                                      15. Greenspan A: Benign bone-forming lesions: osteoma, osteoid osteoma, and osteoblastoma. Clinical, imaging, pathologic, and differential considerations. Skeletal Radiol. 22(7):485-500, 1993
                                                                                      16. Woods ER et al: Reactive soft-tissue mass associated with osteoid osteoma: correlation of MR imaging features with pathologic findings. Radiology. 186(1):221-5, 1993
                                                                                      17. Klein MH et al: Osteoid osteoma: radiologic and pathologic correlation. Skeletal Radiol. 21(1):23-31, 1992
                                                                                      18. Raskas DS et al: Osteoid osteoma and osteoblastoma of the spine. J Spinal Disord. 5(2): 204-11, 1992
                                                                                      19. Afshani E et al: Common causes of low back pain in children. Radiographics. 11(2): 269-91, 1991
                                                                                      20. Kransdorf MJ et al: Osteoid osteoma. Radiographics. 11(4):671-96, 1991
                                                                                      21. Crim JR et al: Widespread inflammatory response to osteoblastoma: the flare phenomenon. Radiology. 177(3):835-6, 1990