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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Definitions
- Osteomalacia: Abnormal mineralization in trabecular and cortical bone
- Rickets: Abnormal mineralization of growth plates
- Only seen in skeletally immature individuals
- Concomitant osteomalacia
IMAGING
General Features
Imaging Recommendations
Radiographic Findings
CT Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
- Calder AD: Radiology of osteogenesis imperfecta, rickets and other bony fragility states. Endocr Dev. 28:56-71, 2015
- Hautmann AH et al: Tumor-induced osteomalacia: an up-to-date review. Curr Rheumatol Rep. 17(6):512, 2015
- Higley M et al: Locally aggressive and multifocal phosphaturic mesenchymal tumors: two unusual cases of tumor-induced osteomalacia. Skeletal Radiol. 44(12):1825-31, 2015
- Jensen EA et al: Determinants of severe metabolic bone disease in very low-birth-weight infants with severe bronchopulmonary dysplasia admitted to a tertiary referral center. Am J Perinatol. 33(1):107-13, 2015
- Watanabe D et al: Osteomalacia, severe thoracic deformities and respiratory failure in a young woman with anorexia nervosa. Intern Med. 54(8):929-34, 2015
- Chapman T et al: Fractures in infants and toddlers with rickets. Pediatr Radiol. 2010 Jul;40(7):1184-9. Epub 2009 Dec 9. Erratum in: Pediatr Radiol. 40(7):1308, 2010
- Sundaram M: Founders lecture 2007: Metabolic bone disease: what has changed in 30 years? Skeletal Radiol. 38(9):841-53, 2009
- Reginato AJ et al: Musculoskeletal manifestations of osteomalacia: report of 26 cases and literature review. Semin Arthritis Rheum. 28(5):287-304, 1999
- Burnstein MI et al: The enthesopathic changes of hypophosphatemic osteomalacia in adults: radiologic findings. AJR Am J Roentgenol. 153(4):785-90, 1989
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Definitions
- Osteomalacia: Abnormal mineralization in trabecular and cortical bone
- Rickets: Abnormal mineralization of growth plates
- Only seen in skeletally immature individuals
- Concomitant osteomalacia
IMAGING
General Features
Imaging Recommendations
Radiographic Findings
CT Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
- Calder AD: Radiology of osteogenesis imperfecta, rickets and other bony fragility states. Endocr Dev. 28:56-71, 2015
- Hautmann AH et al: Tumor-induced osteomalacia: an up-to-date review. Curr Rheumatol Rep. 17(6):512, 2015
- Higley M et al: Locally aggressive and multifocal phosphaturic mesenchymal tumors: two unusual cases of tumor-induced osteomalacia. Skeletal Radiol. 44(12):1825-31, 2015
- Jensen EA et al: Determinants of severe metabolic bone disease in very low-birth-weight infants with severe bronchopulmonary dysplasia admitted to a tertiary referral center. Am J Perinatol. 33(1):107-13, 2015
- Watanabe D et al: Osteomalacia, severe thoracic deformities and respiratory failure in a young woman with anorexia nervosa. Intern Med. 54(8):929-34, 2015
- Chapman T et al: Fractures in infants and toddlers with rickets. Pediatr Radiol. 2010 Jul;40(7):1184-9. Epub 2009 Dec 9. Erratum in: Pediatr Radiol. 40(7):1308, 2010
- Sundaram M: Founders lecture 2007: Metabolic bone disease: what has changed in 30 years? Skeletal Radiol. 38(9):841-53, 2009
- Reginato AJ et al: Musculoskeletal manifestations of osteomalacia: report of 26 cases and literature review. Semin Arthritis Rheum. 28(5):287-304, 1999
- Burnstein MI et al: The enthesopathic changes of hypophosphatemic osteomalacia in adults: radiologic findings. AJR Am J Roentgenol. 153(4):785-90, 1989
