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Musculoskeletal
Diagnosis
Non-Trauma
Bone Marrow
Osteonecrosis
Osteonecrosis of Knee
Osteonecrosis of Knee
Brady K. Huang, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Definitions

            • Osteonecrosis (ON) located within bones of knee; imaging appearance and clinical risks are similar to ON at other sites

          IMAGING

          • Radiographic Findings

            • CT Findings

              • MR Findings

                DIFFERENTIAL DIAGNOSIS

                  CLINICAL ISSUES

                  • Presentation

                    • Demographics

                      Selected References

                      1. Crim J et al: Comparison of radiographic and pathologic diagnosis of osteonecrosis of the femoral head. AJR Am J Roentgenol. 216(4):1014-21, 2021
                      2. Pareek A et al: Spontaneous osteonecrosis/subchondral insufficiency fractures of the knee: high rates of conversion to surgical treatment and arthroplasty. J Bone Joint Surg Am. 102(9):821-9, 2020
                      3. Hussain ZB et al: The role of meniscal tears in spontaneous osteonecrosis of the knee: a systematic review of suspected etiology and a call to revisit nomenclature. Am J Sports Med. 47(2):501-7, 2019
                      4. Gorbachova T et al: Osteochondral lesions of the knee: differentiating the most common entities at MRI. Radiographics. 38(5):1478-95, 2018
                      5. Di Caprio F et al: Postarthroscopy osteonecrosis of the knee: current concepts. Joints. 5(4):229-36, 2017
                      6. Hu LB et al: Osteonecrosis of the femoral head: using CT, MRI and gross specimen to characterize the location, shape and size of the lesion. Br J Radiol. 88(1046):20140508, 2015
                      7. Karim AR et al: Osteonecrosis of the knee: review. Ann Transl Med. 3(1):6, 2015
                      8. 3487233hey MD et al: From the radiologic pathology archives imaging of osteonecrosis: radiologic-pathologic correlation. Radiographics. 34(4):1003-28, 2014
                      9. Russell RD et al: Avoiding patellar complications in total knee replacement. Bone Joint J. 96-B(11 Supple A):84-6, 2014
                      10. Tanaka Y et al: Histological evaluation of spontaneous osteonecrosis of the medial femoral condyle and short-term clinical results of osteochondral autografting: a case series. Knee. 16(2):130-5, 2009
                      11. Zywiel MG et al: Osteonecrosis of the knee: a review of three disorders. Orthop Clin North Am. 40(2):193-211, 2009
                      12. Stevens K et al: Subchondral fractures in osteonecrosis of the femoral head: comparison of radiography, CT, and MR imaging. AJR Am J Roentgenol. 180(2):363-8, 2003
                      13. Narváez J et al: Osteonecrosis of the knee: differences among idiopathic and secondary types. Rheumatology (Oxford). 39(9):982-9, 2000
                      14. Yamamoto T et al: Spontaneous osteonecrosis of the knee: the result of subchondral insufficiency fracture. J Bone Joint Surg Am. 82(6):858-66, 2000
                      15. Sakai T et al: MRI evaluation of steroid- or alcohol-related osteonecrosis of the femoral condyle. Acta Orthop Scand. 69(6):598-602, 1998
                      16. LaPrade RF et al: Idiopathic osteonecrosis of the patella: an unusual cause of pain in the knee. A case report. J Bone Joint Surg Am. 72(9):1414-8, 1990
                      17. Mitchell MD et al: Avascular necrosis of the hip: comparison of MR, CT, and scintigraphy. AJR Am J Roentgenol. 147(1):67-71, 1986
                      Related Anatomy
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                      Related Differential Diagnoses
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                      References
                      Tables

                      Tables

                      KEY FACTS

                      • Terminology

                        • Imaging

                          • Top Differential Diagnoses

                            • Clinical Issues

                              TERMINOLOGY

                              • Definitions

                                • Osteonecrosis (ON) located within bones of knee; imaging appearance and clinical risks are similar to ON at other sites

                              IMAGING

                              • Radiographic Findings

                                • CT Findings

                                  • MR Findings

                                    DIFFERENTIAL DIAGNOSIS

                                      CLINICAL ISSUES

                                      • Presentation

                                        • Demographics

                                          Selected References

                                          1. Crim J et al: Comparison of radiographic and pathologic diagnosis of osteonecrosis of the femoral head. AJR Am J Roentgenol. 216(4):1014-21, 2021
                                          2. Pareek A et al: Spontaneous osteonecrosis/subchondral insufficiency fractures of the knee: high rates of conversion to surgical treatment and arthroplasty. J Bone Joint Surg Am. 102(9):821-9, 2020
                                          3. Hussain ZB et al: The role of meniscal tears in spontaneous osteonecrosis of the knee: a systematic review of suspected etiology and a call to revisit nomenclature. Am J Sports Med. 47(2):501-7, 2019
                                          4. Gorbachova T et al: Osteochondral lesions of the knee: differentiating the most common entities at MRI. Radiographics. 38(5):1478-95, 2018
                                          5. Di Caprio F et al: Postarthroscopy osteonecrosis of the knee: current concepts. Joints. 5(4):229-36, 2017
                                          6. Hu LB et al: Osteonecrosis of the femoral head: using CT, MRI and gross specimen to characterize the location, shape and size of the lesion. Br J Radiol. 88(1046):20140508, 2015
                                          7. Karim AR et al: Osteonecrosis of the knee: review. Ann Transl Med. 3(1):6, 2015
                                          8. 3487233hey MD et al: From the radiologic pathology archives imaging of osteonecrosis: radiologic-pathologic correlation. Radiographics. 34(4):1003-28, 2014
                                          9. Russell RD et al: Avoiding patellar complications in total knee replacement. Bone Joint J. 96-B(11 Supple A):84-6, 2014
                                          10. Tanaka Y et al: Histological evaluation of spontaneous osteonecrosis of the medial femoral condyle and short-term clinical results of osteochondral autografting: a case series. Knee. 16(2):130-5, 2009
                                          11. Zywiel MG et al: Osteonecrosis of the knee: a review of three disorders. Orthop Clin North Am. 40(2):193-211, 2009
                                          12. Stevens K et al: Subchondral fractures in osteonecrosis of the femoral head: comparison of radiography, CT, and MR imaging. AJR Am J Roentgenol. 180(2):363-8, 2003
                                          13. Narváez J et al: Osteonecrosis of the knee: differences among idiopathic and secondary types. Rheumatology (Oxford). 39(9):982-9, 2000
                                          14. Yamamoto T et al: Spontaneous osteonecrosis of the knee: the result of subchondral insufficiency fracture. J Bone Joint Surg Am. 82(6):858-66, 2000
                                          15. Sakai T et al: MRI evaluation of steroid- or alcohol-related osteonecrosis of the femoral condyle. Acta Orthop Scand. 69(6):598-602, 1998
                                          16. LaPrade RF et al: Idiopathic osteonecrosis of the patella: an unusual cause of pain in the knee. A case report. J Bone Joint Surg Am. 72(9):1414-8, 1990
                                          17. Mitchell MD et al: Avascular necrosis of the hip: comparison of MR, CT, and scintigraphy. AJR Am J Roentgenol. 147(1):67-71, 1986