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Osteoporosis
Lubdha M. Shah, MD; Jeffrey S. Ross, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Osteoporosis (OP), sacral insufficiency fracture (SIF), bone marrow (BM)
            • Definitions

              • Decreased bone mass/bone mineral density (BMD)
              • Skeletal disorder characterized by low bone strength and increased risk of fracture

            IMAGING

            • General Features

              • Imaging Recommendations

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Nuclear Medicine Findings

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Image Interpretation Pearls

                                        Selected References

                                        1. Cosman F et al: Clinician's Guide to Prevention and Treatment of Osteoporosis. Osteoporos Int. 25(10):2359-81, 2014
                                        2. Zhang J et al: Use of pharmacologic agents for the primary prevention of osteoporosis among older women with low bone mass. Osteoporos Int. 25(1):317-24, 2014
                                        3. Canalis E: Update in new anabolic therapies for osteoporosis. J Clin Endocrinol Metab. 95(4):1496-504, 2010
                                        4. Lyders EM et al: Imaging and treatment of sacral insufficiency fractures. AJNR Am J Neuroradiol. 31(2):201-10, 2010
                                        5. Unnanuntana A et al: The assessment of fracture risk. J Bone Joint Surg Am. 92(3):743-53, 2010
                                        6. Baur A et al: Diffusion-weighted imaging of bone marrow: current status. Eur Radiol. 13(7):1699-708, 2003
                                        7. Jung HS et al: Discrimination of metastatic from acute osteoporotic compression spinal fractures with MR imaging. Radiographics. 23(1):179-87, 2003
                                        8. Baur A et al: Acute osteoporotic and neoplastic vertebral compression fractures: fluid sign at MR imaging. Radiology. 225(3):730-5, 2002
                                        9. Schmitz A et al: FDG-PET findings of vertebral compression fractures in osteoporosis: preliminary results. Osteoporos Int. 13(9):755-61, 2002
                                        10. Stewart TL et al: Role of genetic factors in the pathogenesis of osteoporosis. J Endocrinol. 166(2):235-45, 2000
                                        11. Hayes CW et al: MR imaging of bone marrow edema pattern: transient osteoporosis, transient bone marrow edema syndrome, or osteonecrosis. Radiographics. 13(5):1001-11; discussion 1012, 1993
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Pathology

                                                • Clinical Issues

                                                  TERMINOLOGY

                                                  • Abbreviations

                                                    • Osteoporosis (OP), sacral insufficiency fracture (SIF), bone marrow (BM)
                                                  • Definitions

                                                    • Decreased bone mass/bone mineral density (BMD)
                                                    • Skeletal disorder characterized by low bone strength and increased risk of fracture

                                                  IMAGING

                                                  • General Features

                                                    • Imaging Recommendations

                                                      • Radiographic Findings

                                                        • CT Findings

                                                          • MR Findings

                                                            • Nuclear Medicine Findings

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Staging, Grading, & Classification

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          • Treatment

                                                                            DIAGNOSTIC CHECKLIST

                                                                            • Image Interpretation Pearls

                                                                              Selected References

                                                                              1. Cosman F et al: Clinician's Guide to Prevention and Treatment of Osteoporosis. Osteoporos Int. 25(10):2359-81, 2014
                                                                              2. Zhang J et al: Use of pharmacologic agents for the primary prevention of osteoporosis among older women with low bone mass. Osteoporos Int. 25(1):317-24, 2014
                                                                              3. Canalis E: Update in new anabolic therapies for osteoporosis. J Clin Endocrinol Metab. 95(4):1496-504, 2010
                                                                              4. Lyders EM et al: Imaging and treatment of sacral insufficiency fractures. AJNR Am J Neuroradiol. 31(2):201-10, 2010
                                                                              5. Unnanuntana A et al: The assessment of fracture risk. J Bone Joint Surg Am. 92(3):743-53, 2010
                                                                              6. Baur A et al: Diffusion-weighted imaging of bone marrow: current status. Eur Radiol. 13(7):1699-708, 2003
                                                                              7. Jung HS et al: Discrimination of metastatic from acute osteoporotic compression spinal fractures with MR imaging. Radiographics. 23(1):179-87, 2003
                                                                              8. Baur A et al: Acute osteoporotic and neoplastic vertebral compression fractures: fluid sign at MR imaging. Radiology. 225(3):730-5, 2002
                                                                              9. Schmitz A et al: FDG-PET findings of vertebral compression fractures in osteoporosis: preliminary results. Osteoporos Int. 13(9):755-61, 2002
                                                                              10. Stewart TL et al: Role of genetic factors in the pathogenesis of osteoporosis. J Endocrinol. 166(2):235-45, 2000
                                                                              11. Hayes CW et al: MR imaging of bone marrow edema pattern: transient osteoporosis, transient bone marrow edema syndrome, or osteonecrosis. Radiographics. 13(5):1001-11; discussion 1012, 1993