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Ovarian Cancer
Brad Perry, MD; Paige Bennett, MD
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      • Diagnostic Checklist

        TERMINOLOGY

        • Definitions

          • Primary ovarian carcinoma
            • Epithelial (90%), stromal (6%), germ cell (3%)
            • Initial mass involves ovary ± fallopian tubes
          • Metastatic spread
            • Can involve pelvic &/or paraaortic nodes
            • Peritoneum
              • Can lead to encasement of reproductive/abdominal organs by malignant tumor
            • Distant metastases include liver, lung

        IMAGING

        • F-18 FDG PET/CT Findings

          • MR Findings

            DIFFERENTIAL DIAGNOSIS

              PATHOLOGY

              • General Features

                • Staging, Grading, & Classification

                  CLINICAL ISSUES

                  • Presentation

                    • Demographics

                      • Natural History & Prognosis

                        • Treatment

                          DIAGNOSTIC CHECKLIST

                          • Image Interpretation Pearls

                            • Reporting Tips

                              Selected References

                              1. Perrone AM et al: Potential prognostic role of 18F-FDG PET/CT in invasive epithelial ovarian cancer relapse. A preliminary study. Cancers (Basel). 11(5), 2019
                              2. Park S et al: Value of F-18 FDG PET/CT in the prediction of overall survival in advanced ovarian cancer after neoadjuvant therapy. J Nuc Med. 59(1):395, 2018
                              3. Khiewvan B et al: An update on the role of PET/CT and PET/MRI in ovarian cancer. Eur J Nucl Med Mol Imaging. 44(6):1079-91, 2017
                              4. Iyer V et al: MRI, CT, and PET/CT for ovarian cancer detection and adnexal lesion characterization. http://www.ajronline.org/doi/full/10.2214/AJR.09.3522. AM J Roentgenology. 194 (2): 311-21, 2010
                              Related Anatomy
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                              Related Differential Diagnoses
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                              References
                              Tables

                              Tables

                              KEY FACTS

                              • Imaging

                                • Top Differential Diagnoses

                                  • Diagnostic Checklist

                                    TERMINOLOGY

                                    • Definitions

                                      • Primary ovarian carcinoma
                                        • Epithelial (90%), stromal (6%), germ cell (3%)
                                        • Initial mass involves ovary ± fallopian tubes
                                      • Metastatic spread
                                        • Can involve pelvic &/or paraaortic nodes
                                        • Peritoneum
                                          • Can lead to encasement of reproductive/abdominal organs by malignant tumor
                                        • Distant metastases include liver, lung

                                    IMAGING

                                    • F-18 FDG PET/CT Findings

                                      • MR Findings

                                        DIFFERENTIAL DIAGNOSIS

                                          PATHOLOGY

                                          • General Features

                                            • Staging, Grading, & Classification

                                              CLINICAL ISSUES

                                              • Presentation

                                                • Demographics

                                                  • Natural History & Prognosis

                                                    • Treatment

                                                      DIAGNOSTIC CHECKLIST

                                                      • Image Interpretation Pearls

                                                        • Reporting Tips

                                                          Selected References

                                                          1. Perrone AM et al: Potential prognostic role of 18F-FDG PET/CT in invasive epithelial ovarian cancer relapse. A preliminary study. Cancers (Basel). 11(5), 2019
                                                          2. Park S et al: Value of F-18 FDG PET/CT in the prediction of overall survival in advanced ovarian cancer after neoadjuvant therapy. J Nuc Med. 59(1):395, 2018
                                                          3. Khiewvan B et al: An update on the role of PET/CT and PET/MRI in ovarian cancer. Eur J Nucl Med Mol Imaging. 44(6):1079-91, 2017
                                                          4. Iyer V et al: MRI, CT, and PET/CT for ovarian cancer detection and adnexal lesion characterization. http://www.ajronline.org/doi/full/10.2214/AJR.09.3522. AM J Roentgenology. 194 (2): 311-21, 2010