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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Definitions
- Malignant tumor of ovary with trophoblastic differentiation
- 2 forms of ovarian choriocarcinoma exist
- Nongestational choriocarcinoma
- Classified as ovarian germ cell tumor
- Tumor may be admixed with other malignant germ cell components
- Gestational choriocarcinoma
- Represent metastasis from primary gestational choriocarcinoma in uterus
- Rarely, may arise from ovarian ectopic pregnancy
- Nongestational choriocarcinoma
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Shaaban AM et al: Ovarian malignant germ cell tumors: cellular classification and clinical and imaging features. Radiographics. 34(3):777-801, 2014
- Lalwani N et al: Rare, miscellaneous primary ovarian neoplasms: spectrum of cross-sectional imaging. Curr Probl Diagn Radiol. 41(2):73-80, 2012
- Peterson CM et al: Teratomas: a multimodality review. Curr Probl Diagn Radiol. 41(6):210-9, 2012
- Shanbhogue AK et al: Clinical syndromes associated with ovarian neoplasms: a comprehensive review. Radiographics. 30(4):903-19, 2010
- Allen SD et al: Radiology of gestational trophoblastic neoplasia. Clin Radiol. 61(4):301-13, 2006
- Koshy M et al: Malignant ovarian mixed germ cell tumour: a rare combination. Biomed Imaging Interv J. 1(2):e10, 2005
- Bazot M et al: Imaging of pure primary ovarian choriocarcinoma. AJR Am J Roentgenol. 182(6):1603-4, 2004
- Ozaki Y et al: Choriocarcinoma of the ovary associated with mucinous cystadenoma. Radiat Med. 19(1):55-9, 2001
- Simsek T et al: Primary pure choriocarcinoma of the ovary in reproductive ages: a case report. Eur J Gynaecol Oncol. 19(3):284-6, 1998
- Sashi R et al: Infantile choriocarcinoma: a case report with MRI, angiography and bone scintigraphy. Pediatr Radiol. 26(12):869-70, 1996
- Brammer HM 3rd et al: From the archives of the AFIP. Malignant germ cell tumors of the ovary: radiologic-pathologic correlation. Radiographics. 10(4):715-24, 1990
- Grover V et al: Primary pure choriocarcinoma of the ovary. Gynecol Obstet Invest. 30(1):61-3, 1990
- Axe SR et al: Choriocarcinoma of the ovary. Obstet Gynecol. 66(1):111-4, 1985
- Jacobs AJ et al: Pure choriocarcinoma of the ovary. Obstet Gynecol Surv. 37(10):603-9, 1982
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Definitions
- Malignant tumor of ovary with trophoblastic differentiation
- 2 forms of ovarian choriocarcinoma exist
- Nongestational choriocarcinoma
- Classified as ovarian germ cell tumor
- Tumor may be admixed with other malignant germ cell components
- Gestational choriocarcinoma
- Represent metastasis from primary gestational choriocarcinoma in uterus
- Rarely, may arise from ovarian ectopic pregnancy
- Nongestational choriocarcinoma
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Shaaban AM et al: Ovarian malignant germ cell tumors: cellular classification and clinical and imaging features. Radiographics. 34(3):777-801, 2014
- Lalwani N et al: Rare, miscellaneous primary ovarian neoplasms: spectrum of cross-sectional imaging. Curr Probl Diagn Radiol. 41(2):73-80, 2012
- Peterson CM et al: Teratomas: a multimodality review. Curr Probl Diagn Radiol. 41(6):210-9, 2012
- Shanbhogue AK et al: Clinical syndromes associated with ovarian neoplasms: a comprehensive review. Radiographics. 30(4):903-19, 2010
- Allen SD et al: Radiology of gestational trophoblastic neoplasia. Clin Radiol. 61(4):301-13, 2006
- Koshy M et al: Malignant ovarian mixed germ cell tumour: a rare combination. Biomed Imaging Interv J. 1(2):e10, 2005
- Bazot M et al: Imaging of pure primary ovarian choriocarcinoma. AJR Am J Roentgenol. 182(6):1603-4, 2004
- Ozaki Y et al: Choriocarcinoma of the ovary associated with mucinous cystadenoma. Radiat Med. 19(1):55-9, 2001
- Simsek T et al: Primary pure choriocarcinoma of the ovary in reproductive ages: a case report. Eur J Gynaecol Oncol. 19(3):284-6, 1998
- Sashi R et al: Infantile choriocarcinoma: a case report with MRI, angiography and bone scintigraphy. Pediatr Radiol. 26(12):869-70, 1996
- Brammer HM 3rd et al: From the archives of the AFIP. Malignant germ cell tumors of the ovary: radiologic-pathologic correlation. Radiographics. 10(4):715-24, 1990
- Grover V et al: Primary pure choriocarcinoma of the ovary. Gynecol Obstet Invest. 30(1):61-3, 1990
- Axe SR et al: Choriocarcinoma of the ovary. Obstet Gynecol. 66(1):111-4, 1985
- Jacobs AJ et al: Pure choriocarcinoma of the ovary. Obstet Gynecol Surv. 37(10):603-9, 1982
