Invagination of ovarian cortical surface epithelium with loss of communication with ovarian surface and subsequent cyst formation
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Laing FC et al: US of the ovary and adnexa: to worry or not to worry? Radiographics. 32(6):1621-39; discussion 1640-2, 2012
Mohaghegh P et al: Imaging strategy for early ovarian cancer: characterization of adnexal masses with conventional and advanced imaging techniques. Radiographics. 32(6):1751-73, 2012
Sharma A et al: Assessing the malignant potential of ovarian inclusion cysts in postmenopausal women within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a prospective cohort study. BJOG. 119(2):207-19, 2012
Levine D et al: Management of asymptomatic ovarian and other adnexal cysts imaged at US: Society of Radiologists in Ultrasound Consensus Conference Statement. Radiology. 256(3):943-54, 2010
Takeuchi M et al: Manifestations of the female reproductive organs on MR images: changes induced by various physiologic states. Radiographics. 30(4):1147, 2010
Dubeau L: The cell of origin of ovarian epithelial tumours. Lancet Oncol. 9(12):1191-7, 2008
Dikensoy E et al: Serum CA-125 is a good predictor of benign disease in patients with postmenopausal ovarian cysts. Eur J Gynaecol Oncol. 28(1):45-7, 2007
McDonald JM et al: The incidental postmenopausal adnexal mass. Clin Obstet Gynecol. 49(3):506-16, 2006
Dørum A et al: Prevalence and histologic diagnosis of adnexal cysts in postmenopausal women: an autopsy study. Am J Obstet Gynecol. 192(1):48-54, 2005
Heller DS et al: Are germinal inclusion cysts markers of ovulation? Gynecol Oncol. 96(2):496-9, 2005
Jung SE et al: CT and MR imaging of ovarian tumors with emphasis on differential diagnosis. Radiographics. 22(6):1305-25, 2002
Feeley KM et al: Precursor lesions of ovarian epithelial malignancy. Histopathology. 38(2):87-95, 2001
Kupfer MC et al: Transvaginal sonographic evaluation of multiple peripherally distributed echogenic foci of the ovary: prevalence and histologic correlation. AJR Am J Roentgenol. 171(2):483-6, 1998
Brandt KR et al: Focal calcifications in otherwise ultrasonographically normal ovaries. Radiology. 198(2):415-7, 1996
Outwater EK et al: Normal adnexa uteri specimens: anatomic basis of MR imaging features. Radiology. 201(3):751-5, 1996
Atri M et al: Endovaginal sonographic appearance of benign ovarian masses. Radiographics. 14(4):747-60; discussion 761-2, 1994
Mittal KR et al: Contralateral ovary in unilateral ovarian carcinoma: a search for preneoplastic lesions. Int J Gynecol Pathol. 12(1):59-63, 1993
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Abbreviations
Ovarian inclusion cyst (OIC)
Synonyms
Epithelial inclusion cyst
Cortical inclusion cyst
Germinal inclusion cyst
Ovarian epithelial inclusions
Definitions
Invagination of ovarian cortical surface epithelium with loss of communication with ovarian surface and subsequent cyst formation
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Laing FC et al: US of the ovary and adnexa: to worry or not to worry? Radiographics. 32(6):1621-39; discussion 1640-2, 2012
Mohaghegh P et al: Imaging strategy for early ovarian cancer: characterization of adnexal masses with conventional and advanced imaging techniques. Radiographics. 32(6):1751-73, 2012
Sharma A et al: Assessing the malignant potential of ovarian inclusion cysts in postmenopausal women within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a prospective cohort study. BJOG. 119(2):207-19, 2012
Levine D et al: Management of asymptomatic ovarian and other adnexal cysts imaged at US: Society of Radiologists in Ultrasound Consensus Conference Statement. Radiology. 256(3):943-54, 2010
Takeuchi M et al: Manifestations of the female reproductive organs on MR images: changes induced by various physiologic states. Radiographics. 30(4):1147, 2010
Dubeau L: The cell of origin of ovarian epithelial tumours. Lancet Oncol. 9(12):1191-7, 2008
Dikensoy E et al: Serum CA-125 is a good predictor of benign disease in patients with postmenopausal ovarian cysts. Eur J Gynaecol Oncol. 28(1):45-7, 2007
McDonald JM et al: The incidental postmenopausal adnexal mass. Clin Obstet Gynecol. 49(3):506-16, 2006
Dørum A et al: Prevalence and histologic diagnosis of adnexal cysts in postmenopausal women: an autopsy study. Am J Obstet Gynecol. 192(1):48-54, 2005
Heller DS et al: Are germinal inclusion cysts markers of ovulation? Gynecol Oncol. 96(2):496-9, 2005
Jung SE et al: CT and MR imaging of ovarian tumors with emphasis on differential diagnosis. Radiographics. 22(6):1305-25, 2002
Feeley KM et al: Precursor lesions of ovarian epithelial malignancy. Histopathology. 38(2):87-95, 2001
Kupfer MC et al: Transvaginal sonographic evaluation of multiple peripherally distributed echogenic foci of the ovary: prevalence and histologic correlation. AJR Am J Roentgenol. 171(2):483-6, 1998
Brandt KR et al: Focal calcifications in otherwise ultrasonographically normal ovaries. Radiology. 198(2):415-7, 1996
Outwater EK et al: Normal adnexa uteri specimens: anatomic basis of MR imaging features. Radiology. 201(3):751-5, 1996
Atri M et al: Endovaginal sonographic appearance of benign ovarian masses. Radiographics. 14(4):747-60; discussion 761-2, 1994
Mittal KR et al: Contralateral ovary in unilateral ovarian carcinoma: a search for preneoplastic lesions. Int J Gynecol Pathol. 12(1):59-63, 1993
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