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Pediatrics
Diagnosis
Genitourinary
Uterine and Ovarian Abnormalities
Ovarian Malignancies of Childhood
Ovarian Malignancies of Childhood
Alexander J. Towbin, MD
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KEY FACTS
Imaging
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Definitions
Germ cell tumors
Mature ovarian teratoma, immature ovarian teratoma, ovarian dysgerminoma, yolk sac tumor, choriocarcinoma
Sex cord-stromal tumors
Juvenile granulosa-theca cell tumor, Sertoli-Leydig cell tumor
Epithelial tumors
Serous & mucinous tumors
Can be differentiated into benign, borderline, & malignant, depending on histology
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Staging, Grading, & Classification
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Kelleher CM et al: Adnexal masses in children and adolescents. Clin Obstet Gynecol. 58(1):76-92, 2015
Doros LA et al: DICER1 mutations in childhood cystic nephroma and its relationship to DICER1-renal sarcoma. Mod Pathol. 27(9):1267-80, 2014
Heo SH et al: Review of ovarian tumors in children and adolescents: radiologic-pathologic correlation. Radiographics. 34(7):2039-55, 2014
Shaaban AM et al: Ovarian malignant germ cell tumors: cellular classification and clinical and imaging features. Radiographics. 34(3):777-801, 2014
Related Anatomy
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References
Tables
Tables
KEY FACTS
Imaging
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Definitions
Germ cell tumors
Mature ovarian teratoma, immature ovarian teratoma, ovarian dysgerminoma, yolk sac tumor, choriocarcinoma
Sex cord-stromal tumors
Juvenile granulosa-theca cell tumor, Sertoli-Leydig cell tumor
Epithelial tumors
Serous & mucinous tumors
Can be differentiated into benign, borderline, & malignant, depending on histology
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Staging, Grading, & Classification
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Kelleher CM et al: Adnexal masses in children and adolescents. Clin Obstet Gynecol. 58(1):76-92, 2015
Doros LA et al: DICER1 mutations in childhood cystic nephroma and its relationship to DICER1-renal sarcoma. Mod Pathol. 27(9):1267-80, 2014
Heo SH et al: Review of ovarian tumors in children and adolescents: radiologic-pathologic correlation. Radiographics. 34(7):2039-55, 2014
Shaaban AM et al: Ovarian malignant germ cell tumors: cellular classification and clinical and imaging features. Radiographics. 34(3):777-801, 2014
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