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Ovarian Malignancies of Childhood
Alexander J. Towbin, MD
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KEY FACTS

  • Imaging

    • Pathology

      • Clinical Issues

        • Diagnostic Checklist

          TERMINOLOGY

          • Definitions

            • Germ cell tumors
              • Mature ovarian teratoma, immature ovarian teratoma, ovarian dysgerminoma, yolk sac tumor, choriocarcinoma
            • Sex cord-stromal tumors
              • Juvenile granulosa-theca cell tumor, Sertoli-Leydig cell tumor
            • Epithelial tumors
              • Serous & mucinous tumors
              • Can be differentiated into benign, borderline, & malignant, depending on histology

          IMAGING

          • General Features

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • Staging, Grading, & Classification

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Image Interpretation Pearls

                                    Selected References

                                    1. Kelleher CM et al: Adnexal masses in children and adolescents. Clin Obstet Gynecol. 58(1):76-92, 2015
                                    2. Doros LA et al: DICER1 mutations in childhood cystic nephroma and its relationship to DICER1-renal sarcoma. Mod Pathol. 27(9):1267-80, 2014
                                    3. Heo SH et al: Review of ovarian tumors in children and adolescents: radiologic-pathologic correlation. Radiographics. 34(7):2039-55, 2014
                                    4. Shaaban AM et al: Ovarian malignant germ cell tumors: cellular classification and clinical and imaging features. Radiographics. 34(3):777-801, 2014
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Imaging

                                      • Pathology

                                        • Clinical Issues

                                          • Diagnostic Checklist

                                            TERMINOLOGY

                                            • Definitions

                                              • Germ cell tumors
                                                • Mature ovarian teratoma, immature ovarian teratoma, ovarian dysgerminoma, yolk sac tumor, choriocarcinoma
                                              • Sex cord-stromal tumors
                                                • Juvenile granulosa-theca cell tumor, Sertoli-Leydig cell tumor
                                              • Epithelial tumors
                                                • Serous & mucinous tumors
                                                • Can be differentiated into benign, borderline, & malignant, depending on histology

                                            IMAGING

                                            • General Features

                                              • Radiographic Findings

                                                • CT Findings

                                                  • MR Findings

                                                    • Ultrasonographic Findings

                                                      • Imaging Recommendations

                                                        DIFFERENTIAL DIAGNOSIS

                                                          PATHOLOGY

                                                          • Staging, Grading, & Classification

                                                            CLINICAL ISSUES

                                                            • Presentation

                                                              • Demographics

                                                                • Natural History & Prognosis

                                                                  • Treatment

                                                                    DIAGNOSTIC CHECKLIST

                                                                    • Image Interpretation Pearls

                                                                      Selected References

                                                                      1. Kelleher CM et al: Adnexal masses in children and adolescents. Clin Obstet Gynecol. 58(1):76-92, 2015
                                                                      2. Doros LA et al: DICER1 mutations in childhood cystic nephroma and its relationship to DICER1-renal sarcoma. Mod Pathol. 27(9):1267-80, 2014
                                                                      3. Heo SH et al: Review of ovarian tumors in children and adolescents: radiologic-pathologic correlation. Radiographics. 34(7):2039-55, 2014
                                                                      4. Shaaban AM et al: Ovarian malignant germ cell tumors: cellular classification and clinical and imaging features. Radiographics. 34(3):777-801, 2014