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Ovarian Serous Carcinoma
Akram M. Shaaban, MBBCh; Oguz Akin, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Low-grade serous carcinoma (LGSC)
              • High-grade serous carcinoma (HGSC)
            • Definitions

              • Classified as malignant ovarian epithelial tumor

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            Selected References

                                            1. Chung HH et al: Preoperative [F]FDG PET/CT predicts recurrence in patients with epithelial ovarian cancer. J Gynecol Oncol. 23(1):28-34, 2012
                                            2. Lalwani N et al: Histologic, molecular, and cytogenetic features of ovarian cancers: implications for diagnosis and treatment. Radiographics. 31(3):625-46, 2011
                                            3. Shin JE et al: The serum CA-125 concentration data assists in evaluating CT imaging information when used to differentiate borderline ovarian tumor from malignant epithelial ovarian tumors. Korean J Radiol. 12(4):456-62, 2011
                                            4. Bige O et al: Collision tumor: serous cystadenocarcinoma and dermoid cyst in the same ovary. Arch Gynecol Obstet. 279(5):767-70, 2009
                                            5. Acs G: Serous and mucinous borderline (low malignant potential) tumors of the ovary. Am J Clin Pathol. 123 Suppl:S13-57, 2005
                                            6. Dexeus S et al: Conservative management of epithelial ovarian cancer. Eur J Gynaecol Oncol. 26(5):473-8, 2005
                                            7. Rabban JT et al: Current issues in the pathology of ovarian cancer. J Reprod Med. 50(6):467-74, 2005
                                            8. Sohaib SA et al: The role of magnetic resonance imaging and ultrasound in patients with adnexal masses. Clin Radiol. 60(3):340-8, 2005
                                            9. Kaku T et al: Histological classification of ovarian cancer. Med Electron Microsc. 36(1):9-17, 2003
                                            10. Togashi K. Related Articles et al: Ovarian cancer: the clinical role of US, CT, and MRI. Eur Radiol. 13 Suppl 4:L87-104, 2003
                                            11. Deavers MT et al: Micropapillary and cribriform patterns in ovarian serous tumors of low malignant potential: a study of 99 advanced stage cases. Am J Surg Pathol. 26(9):1129-41, 2002
                                            12. Jung SE et al: CT and MR imaging of ovarian tumors with emphasis on differential diagnosis. Radiographics. 22(6):1305-25, 2002
                                            13. Sawicki W et al: Preoperative discrimination between malignant and benign adnexal masses with transvaginal ultrasonography and colour blood flow imaging. Eur J Gynaecol Oncol. 22(2):137-42, 2001
                                            14. Jeong YY et al: Imaging evaluation of ovarian masses. Radiographics. 20(5):1445-70, 2000
                                            15. Kawamoto S et al: CT of epithelial ovarian tumors. Radiographics. 19 Spec No:S85-102; quiz S263-4, 1999
                                            16. Kurtz AB et al: Diagnosis and staging of ovarian cancer: comparative values of Doppler and conventional US, CT, and MR imaging correlated with surgery and histopathologic analysis--report of the Radiology Diagnostic Oncology Group. Radiology. 212(1):19-27, 1999
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Pathology

                                                    • Clinical Issues

                                                      TERMINOLOGY

                                                      • Abbreviations

                                                        • Low-grade serous carcinoma (LGSC)
                                                        • High-grade serous carcinoma (HGSC)
                                                      • Definitions

                                                        • Classified as malignant ovarian epithelial tumor

                                                      IMAGING

                                                      • General Features

                                                        • CT Findings

                                                          • MR Findings

                                                            • Ultrasonographic Findings

                                                              • Nuclear Medicine Findings

                                                                • Imaging Recommendations

                                                                  DIFFERENTIAL DIAGNOSIS

                                                                    PATHOLOGY

                                                                    • General Features

                                                                      • Staging, Grading, & Classification

                                                                        • Gross Pathologic & Surgical Features

                                                                          • Microscopic Features

                                                                            CLINICAL ISSUES

                                                                            • Presentation

                                                                              • Demographics

                                                                                • Natural History & Prognosis

                                                                                  • Treatment

                                                                                    DIAGNOSTIC CHECKLIST

                                                                                    • Consider

                                                                                      Selected References

                                                                                      1. Chung HH et al: Preoperative [F]FDG PET/CT predicts recurrence in patients with epithelial ovarian cancer. J Gynecol Oncol. 23(1):28-34, 2012
                                                                                      2. Lalwani N et al: Histologic, molecular, and cytogenetic features of ovarian cancers: implications for diagnosis and treatment. Radiographics. 31(3):625-46, 2011
                                                                                      3. Shin JE et al: The serum CA-125 concentration data assists in evaluating CT imaging information when used to differentiate borderline ovarian tumor from malignant epithelial ovarian tumors. Korean J Radiol. 12(4):456-62, 2011
                                                                                      4. Bige O et al: Collision tumor: serous cystadenocarcinoma and dermoid cyst in the same ovary. Arch Gynecol Obstet. 279(5):767-70, 2009
                                                                                      5. Acs G: Serous and mucinous borderline (low malignant potential) tumors of the ovary. Am J Clin Pathol. 123 Suppl:S13-57, 2005
                                                                                      6. Dexeus S et al: Conservative management of epithelial ovarian cancer. Eur J Gynaecol Oncol. 26(5):473-8, 2005
                                                                                      7. Rabban JT et al: Current issues in the pathology of ovarian cancer. J Reprod Med. 50(6):467-74, 2005
                                                                                      8. Sohaib SA et al: The role of magnetic resonance imaging and ultrasound in patients with adnexal masses. Clin Radiol. 60(3):340-8, 2005
                                                                                      9. Kaku T et al: Histological classification of ovarian cancer. Med Electron Microsc. 36(1):9-17, 2003
                                                                                      10. Togashi K. Related Articles et al: Ovarian cancer: the clinical role of US, CT, and MRI. Eur Radiol. 13 Suppl 4:L87-104, 2003
                                                                                      11. Deavers MT et al: Micropapillary and cribriform patterns in ovarian serous tumors of low malignant potential: a study of 99 advanced stage cases. Am J Surg Pathol. 26(9):1129-41, 2002
                                                                                      12. Jung SE et al: CT and MR imaging of ovarian tumors with emphasis on differential diagnosis. Radiographics. 22(6):1305-25, 2002
                                                                                      13. Sawicki W et al: Preoperative discrimination between malignant and benign adnexal masses with transvaginal ultrasonography and colour blood flow imaging. Eur J Gynaecol Oncol. 22(2):137-42, 2001
                                                                                      14. Jeong YY et al: Imaging evaluation of ovarian masses. Radiographics. 20(5):1445-70, 2000
                                                                                      15. Kawamoto S et al: CT of epithelial ovarian tumors. Radiographics. 19 Spec No:S85-102; quiz S263-4, 1999
                                                                                      16. Kurtz AB et al: Diagnosis and staging of ovarian cancer: comparative values of Doppler and conventional US, CT, and MR imaging correlated with surgery and histopathologic analysis--report of the Radiology Diagnostic Oncology Group. Radiology. 212(1):19-27, 1999