link
Bookmarks
Pediatrics
Diagnosis
Genitourinary
Uterine and Ovarian Abnormalities
Ovarian Teratoma
Ovarian Teratoma
Sara M. O'Hara, MD, FAAP
To access 4,300 diagnoses written by the world's leading experts in radiology.Try it free - 15 days
0
5
3
3

KEY FACTS

  • Terminology

    • Imaging

      • Pathology

        • Clinical Issues

          TERMINOLOGY

          • Synonyms

            • Dermoid tumor, dermoid cyst, cystic teratoma

          • Definitions

            • Teratomas are made up of various parenchymal cell types from > 1 germ layer, usually all 3
            • Teratomas generally lie in midline or paraxial & arise from totipotential cells
            • Term dermoid comes from skin-like lining found in many of these tumors

          IMAGING

          • General Features

            • Radiographic Findings

              • Ultrasonographic Findings

                • CT Findings

                  • MR Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      Selected References

                                      1. Billmire D et al: Imaging appearance of nongerminoma pediatric ovarian germ cell tumors does not discriminate benign from malignant histology. J Pediatr Adolesc Gynecol. 34(3):383-6, 2020
                                      2. Brind'Amour A et al: Recurrent high-grade ovarian immature teratoma with peritoneal dissemination. J Pediatr Adolesc Gynecol. 33(5):586-9, 2020
                                      3. Hanafy AK et al: Imaging in pediatric ovarian tumors. Abdom Radiol (NY). 45(2):520-36, 2020
                                      4. Imran H et al: Growing teratoma syndrome after chemotherapy for ovarian immature teratoma. J Pediatr Hematol Oncol. 42(7):e630-3, 2020
                                      5. Park C et al: Pediatric whole body MRI detects causative ovarian teratoma in opsoclonus myoclonus syndrome. Radiol Case Rep. 15(3):204-9, 2020
                                      6. Szymon O et al: Ovarian sparing surgery in mature ovarian teratomas in children: a 20-year single-center experience. Eur J Pediatr Surg. 31(1):2-7, 2020
                                      7. Lala SV et al: Ovarian neoplasms of childhood. Pediatr Radiol. 49(11):1463-75, 2019
                                      8. Faure-Conter C et al: Immature ovarian teratoma: when to give adjuvant therapy? J Pediatr Hematol Oncol. 39(7):487-9, 2017
                                      9. Gonzalez DO et al: Management of benign ovarian lesions in girls: a trend toward fewer oophorectomies. Curr Opin Obstet Gynecol. 29(5):289-94, 2017
                                      10. Pensabene M et al: An uncommon case of adolescent ovarian teratoma incarcerated in inguinal hernia. Case Rep Pediatr. 2016:4534053, 2016
                                      11. Hayes-Jordan A et al: Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in pediatric ovarian tumors: a novel treatment approach. Pediatr Surg Int. 32(1):71-3, 2016
                                      12. Hsu MH et al: Paraneoplastic neurological disorders in children with benign ovarian tumors. Brain Dev. 36(3):248-53, 2014
                                      13. Salvucci A et al: Pediatric anti-NMDA (N-methyl D-aspartate) receptor encephalitis. Pediatr Neurol. 50(5):507-10, 2014
                                      14. Loh AH et al: Diagnostic accuracy of preoperative alpha-fetoprotein as an ovarian tumor marker in children and adolescents: not as good as we thought? Pediatr Surg Int. 29(7):709-13, 2013
                                      15. Chabaud-Williamson M et al: Ovarian-sparing surgery for ovarian teratoma in children. Pediatr Blood Cancer. 57(3):429-34, 2011
                                      16. Epelman M et al: Imaging of pediatric ovarian neoplasms. Pediatr Radiol. 41(9):1085-99, 2011
                                      17. Alotaibi MO et al: Imaging of ovarian teratomas in children: a 9-year review. Can Assoc Radiol J. 61(1):23-8, 2010
                                      18. Poloni C et al: Severe childhood encephalopathy with dyskinesia and prolonged cognitive disturbances: evidence for anti-N-methyl-D-aspartate receptor encephalitis. Dev Med Child Neurol. 52(5):e78-82, 2010
                                      19. De Nayer AR et al: A subacute behavioral disorder in a female adolescent. Autoimmune anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma. Biol Psychiatry. 66(6):e13-4, 2009
                                      20. Saba L et al: Mature and immature ovarian teratomas: CT, US and MR imaging characteristics. Eur J Radiol. 72(3):454-63, 2009
                                      21. Islam S et al: Management and outcomes of ovarian masses in children and adolescents. Am Surg. 74(11):1062-5, 2008
                                      22. Park SB et al: Imaging findings of complications and unusual manifestations of ovarian teratomas. Radiographics. 28(4):969-83, 2008
                                      23. Benoit MF et al: Recurrent mature cystic ovarian teratoma in adolescence: atypical case of the growing teratoma syndrome. Obstet Gynecol. 105(5 Pt 2):1264-6, 2005
                                      24. Lai CH et al: Outcome and prognostic factors in ovarian germ cell malignancies. Gynecol Oncol. 96(3):784-91, 2005
                                      25. Phupong V et al: Ovarian teratoma with diffused peritoneal reactions mimicking advanced ovarian malignancy. Arch Gynecol Obstet. 270(3):189-91, 2004
                                      26. Rha SE et al: Atypical CT and MRI manifestations of mature ovarian cystic teratomas. AJR Am J Roentgenol. 183(3):743-50, 2004
                                      27. Umesaki N et al: MR and ultrasound imaging of floating globules in mature ovarian cystic teratoma. Gynecol Obstet Invest. 58(3):130-2, 2004
                                      28. PDQ Pediatric Treatment Editorial Board: Childhood extracranial germ cell tumors treatment (PDQ®): Health Professional Version, 2002
                                      Related Anatomy
                                      Loading...
                                      Related Differential Diagnoses
                                      Loading...
                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Pathology

                                            • Clinical Issues

                                              TERMINOLOGY

                                              • Synonyms

                                                • Dermoid tumor, dermoid cyst, cystic teratoma

                                              • Definitions

                                                • Teratomas are made up of various parenchymal cell types from > 1 germ layer, usually all 3
                                                • Teratomas generally lie in midline or paraxial & arise from totipotential cells
                                                • Term dermoid comes from skin-like lining found in many of these tumors

                                              IMAGING

                                              • General Features

                                                • Radiographic Findings

                                                  • Ultrasonographic Findings

                                                    • CT Findings

                                                      • MR Findings

                                                        • Imaging Recommendations

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • General Features

                                                              • Gross Pathologic & Surgical Features

                                                                • Microscopic Features

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Demographics

                                                                      • Natural History & Prognosis

                                                                        • Treatment

                                                                          Selected References

                                                                          1. Billmire D et al: Imaging appearance of nongerminoma pediatric ovarian germ cell tumors does not discriminate benign from malignant histology. J Pediatr Adolesc Gynecol. 34(3):383-6, 2020
                                                                          2. Brind'Amour A et al: Recurrent high-grade ovarian immature teratoma with peritoneal dissemination. J Pediatr Adolesc Gynecol. 33(5):586-9, 2020
                                                                          3. Hanafy AK et al: Imaging in pediatric ovarian tumors. Abdom Radiol (NY). 45(2):520-36, 2020
                                                                          4. Imran H et al: Growing teratoma syndrome after chemotherapy for ovarian immature teratoma. J Pediatr Hematol Oncol. 42(7):e630-3, 2020
                                                                          5. Park C et al: Pediatric whole body MRI detects causative ovarian teratoma in opsoclonus myoclonus syndrome. Radiol Case Rep. 15(3):204-9, 2020
                                                                          6. Szymon O et al: Ovarian sparing surgery in mature ovarian teratomas in children: a 20-year single-center experience. Eur J Pediatr Surg. 31(1):2-7, 2020
                                                                          7. Lala SV et al: Ovarian neoplasms of childhood. Pediatr Radiol. 49(11):1463-75, 2019
                                                                          8. Faure-Conter C et al: Immature ovarian teratoma: when to give adjuvant therapy? J Pediatr Hematol Oncol. 39(7):487-9, 2017
                                                                          9. Gonzalez DO et al: Management of benign ovarian lesions in girls: a trend toward fewer oophorectomies. Curr Opin Obstet Gynecol. 29(5):289-94, 2017
                                                                          10. Pensabene M et al: An uncommon case of adolescent ovarian teratoma incarcerated in inguinal hernia. Case Rep Pediatr. 2016:4534053, 2016
                                                                          11. Hayes-Jordan A et al: Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in pediatric ovarian tumors: a novel treatment approach. Pediatr Surg Int. 32(1):71-3, 2016
                                                                          12. Hsu MH et al: Paraneoplastic neurological disorders in children with benign ovarian tumors. Brain Dev. 36(3):248-53, 2014
                                                                          13. Salvucci A et al: Pediatric anti-NMDA (N-methyl D-aspartate) receptor encephalitis. Pediatr Neurol. 50(5):507-10, 2014
                                                                          14. Loh AH et al: Diagnostic accuracy of preoperative alpha-fetoprotein as an ovarian tumor marker in children and adolescents: not as good as we thought? Pediatr Surg Int. 29(7):709-13, 2013
                                                                          15. Chabaud-Williamson M et al: Ovarian-sparing surgery for ovarian teratoma in children. Pediatr Blood Cancer. 57(3):429-34, 2011
                                                                          16. Epelman M et al: Imaging of pediatric ovarian neoplasms. Pediatr Radiol. 41(9):1085-99, 2011
                                                                          17. Alotaibi MO et al: Imaging of ovarian teratomas in children: a 9-year review. Can Assoc Radiol J. 61(1):23-8, 2010
                                                                          18. Poloni C et al: Severe childhood encephalopathy with dyskinesia and prolonged cognitive disturbances: evidence for anti-N-methyl-D-aspartate receptor encephalitis. Dev Med Child Neurol. 52(5):e78-82, 2010
                                                                          19. De Nayer AR et al: A subacute behavioral disorder in a female adolescent. Autoimmune anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma. Biol Psychiatry. 66(6):e13-4, 2009
                                                                          20. Saba L et al: Mature and immature ovarian teratomas: CT, US and MR imaging characteristics. Eur J Radiol. 72(3):454-63, 2009
                                                                          21. Islam S et al: Management and outcomes of ovarian masses in children and adolescents. Am Surg. 74(11):1062-5, 2008
                                                                          22. Park SB et al: Imaging findings of complications and unusual manifestations of ovarian teratomas. Radiographics. 28(4):969-83, 2008
                                                                          23. Benoit MF et al: Recurrent mature cystic ovarian teratoma in adolescence: atypical case of the growing teratoma syndrome. Obstet Gynecol. 105(5 Pt 2):1264-6, 2005
                                                                          24. Lai CH et al: Outcome and prognostic factors in ovarian germ cell malignancies. Gynecol Oncol. 96(3):784-91, 2005
                                                                          25. Phupong V et al: Ovarian teratoma with diffused peritoneal reactions mimicking advanced ovarian malignancy. Arch Gynecol Obstet. 270(3):189-91, 2004
                                                                          26. Rha SE et al: Atypical CT and MRI manifestations of mature ovarian cystic teratomas. AJR Am J Roentgenol. 183(3):743-50, 2004
                                                                          27. Umesaki N et al: MR and ultrasound imaging of floating globules in mature ovarian cystic teratoma. Gynecol Obstet Invest. 58(3):130-2, 2004
                                                                          28. PDQ Pediatric Treatment Editorial Board: Childhood extracranial germ cell tumors treatment (PDQ®): Health Professional Version, 2002