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KEY FACTS
Terminology
Imaging
Clinical Issues
TERMINOLOGY
Abbreviations
- Mixed connective tissue disease (MCTD)
Synonyms
- Undifferentiated connective tissue disease (preferred term); overlap syndrome
Definitions
- Combination or overlap of clinical symptoms
- Plus high titers of serum antibodies that react with nuclear ribonuclear protein (U1-RNP)
- Overlap syndrome: Systemic sclerosis (PSS) & inflammatory myositis
- MCTD: Systemic lupus erythematosus (SLE) & PSS & polymyositis
- Combination or overlap of clinical symptoms
IMAGING
General Features
PATHOLOGY
General Features
CLINICAL ISSUES
Presentation
Natural History & Prognosis
Treatment
Selected References
- Breda L et al: Laboratory tests in the diagnosis and follow-up of pediatric rheumatic diseases: an update. Semin Arthritis Rheum. 40(1):53-72, 2010
- Antoniou KM et al: Pivotal clinical dilemmas in collagen vascular diseases associated with interstitial lung involvement. Eur Respir J. 33(4):882-96, 2009
- Schulze M et al: MRI findings in inflammatory muscle diseases and their noninflammatory mimics. AJR Am J Roentgenol. 192(6):1708-16, 2009
- Swart JF et al: Diagnostic workup for mixed connective tissue disease in childhood. Isr Med Assoc J. 10(8-9):650-2, 2008
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Clinical Issues
TERMINOLOGY
Abbreviations
- Mixed connective tissue disease (MCTD)
Synonyms
- Undifferentiated connective tissue disease (preferred term); overlap syndrome
Definitions
- Combination or overlap of clinical symptoms
- Plus high titers of serum antibodies that react with nuclear ribonuclear protein (U1-RNP)
- Overlap syndrome: Systemic sclerosis (PSS) & inflammatory myositis
- MCTD: Systemic lupus erythematosus (SLE) & PSS & polymyositis
- Combination or overlap of clinical symptoms
IMAGING
General Features
PATHOLOGY
General Features
CLINICAL ISSUES
Presentation
Natural History & Prognosis
Treatment
Selected References
- Breda L et al: Laboratory tests in the diagnosis and follow-up of pediatric rheumatic diseases: an update. Semin Arthritis Rheum. 40(1):53-72, 2010
- Antoniou KM et al: Pivotal clinical dilemmas in collagen vascular diseases associated with interstitial lung involvement. Eur Respir J. 33(4):882-96, 2009
- Schulze M et al: MRI findings in inflammatory muscle diseases and their noninflammatory mimics. AJR Am J Roentgenol. 192(6):1708-16, 2009
- Swart JF et al: Diagnostic workup for mixed connective tissue disease in childhood. Isr Med Assoc J. 10(8-9):650-2, 2008
