Characterized by bony expansion with variable destruction ± sclerosis
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Cronin O et al: Characteristics of early Paget's disease in SQSTM1 mutation carriers: baseline analysis of the ZiPP study cohort. J Bone Miner Res. ePub, 2020
Omar AT 2nd et al: Management of hydrocephalus in Paget's disease of bone: systematic review and illustrative case. World Neurosurg. 135:e640-9, 2020
Bou Antoun M et al: The lucent (CT) and enhancing (MR) rim, a sign of Paget's disease of the skull: case report. Skeletal Radiol. 47(11):1567-70, 2018
Kravets I: Paget's disease of bone: diagnosis and treatment. Am J Med. 131(11):1298-303, 2018
Czerniak B et al. Dorfman and Czerniak's Bone Tumors. Philadelphia, PA: Elsevier, 2016
Sandford A et al: The 'cotton wool' sign in paget's disease of the skull. QJM. 109(2):131, 2016
Wodajo FM: Top five lesions that do not need referral to orthopedic oncology. Orthop Clin North Am. 46(2):303-14, 2015
Galson DL et al: Pathobiology of Paget's disease of bone. J Bone Metab. 21(2):85-98, 2014
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
Paget disease (PD)
Synonyms
Osteitis deformans
Definitions
Chronic metabolic skeletal disorder
Characterized by bony expansion with variable destruction ± sclerosis
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Cronin O et al: Characteristics of early Paget's disease in SQSTM1 mutation carriers: baseline analysis of the ZiPP study cohort. J Bone Miner Res. ePub, 2020
Omar AT 2nd et al: Management of hydrocephalus in Paget's disease of bone: systematic review and illustrative case. World Neurosurg. 135:e640-9, 2020
Bou Antoun M et al: The lucent (CT) and enhancing (MR) rim, a sign of Paget's disease of the skull: case report. Skeletal Radiol. 47(11):1567-70, 2018
Kravets I: Paget's disease of bone: diagnosis and treatment. Am J Med. 131(11):1298-303, 2018
Czerniak B et al. Dorfman and Czerniak's Bone Tumors. Philadelphia, PA: Elsevier, 2016
Sandford A et al: The 'cotton wool' sign in paget's disease of the skull. QJM. 109(2):131, 2016
Wodajo FM: Top five lesions that do not need referral to orthopedic oncology. Orthop Clin North Am. 46(2):303-14, 2015
Galson DL et al: Pathobiology of Paget's disease of bone. J Bone Metab. 21(2):85-98, 2014
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