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Paget Disease
Anne G. Osborn, MD, FACR; Miral D. Jhaveri, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Paget disease (PD)
            • Synonyms

              • Osteitis deformans
            • Definitions

              • Chronic metabolic skeletal disorder
              • Characterized by bony expansion with variable destruction ± sclerosis

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        Selected References

                                        1. Wodajo FM: Top Five Lesions That Do Not Need Referral to Orthopedic Oncology. Orthop Clin North Am. 46(2):303-314, 2015
                                        2. Galson DL et al: Pathobiology of Paget's Disease of Bone. J Bone Metab. 21(2):85-98, 2014
                                        3. Griz L et al: Diagnosis and management of Paget?s disease of bone. Arq Bras Endocrinol Metabol. 58(6):587-99, 2014
                                        4. Gruener G et al: Paget's disease of bone. Handb Clin Neurol. 119:529-40, 2014
                                        5. Guañabens N et al: Implications of a new radiological approach for the assessment of Paget disease. Calcif Tissue Int. 91(6):409-15, 2012
                                        6. Bender IB: Paget's disease. J Endod. 29(11):720-3, 2003
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Pathology

                                                • Clinical Issues

                                                  TERMINOLOGY

                                                  • Abbreviations

                                                    • Paget disease (PD)
                                                  • Synonyms

                                                    • Osteitis deformans
                                                  • Definitions

                                                    • Chronic metabolic skeletal disorder
                                                    • Characterized by bony expansion with variable destruction ± sclerosis

                                                  IMAGING

                                                  • General Features

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • MR Findings

                                                          • Nuclear Medicine Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              Selected References

                                                                              1. Wodajo FM: Top Five Lesions That Do Not Need Referral to Orthopedic Oncology. Orthop Clin North Am. 46(2):303-314, 2015
                                                                              2. Galson DL et al: Pathobiology of Paget's Disease of Bone. J Bone Metab. 21(2):85-98, 2014
                                                                              3. Griz L et al: Diagnosis and management of Paget?s disease of bone. Arq Bras Endocrinol Metabol. 58(6):587-99, 2014
                                                                              4. Gruener G et al: Paget's disease of bone. Handb Clin Neurol. 119:529-40, 2014
                                                                              5. Guañabens N et al: Implications of a new radiological approach for the assessment of Paget disease. Calcif Tissue Int. 91(6):409-15, 2012
                                                                              6. Bender IB: Paget's disease. J Endod. 29(11):720-3, 2003