Glycogen-rich, microcystic, or macrocystic serous adenoma
Definitions
Benign pancreatic tumors lined by glycogen-rich cells that arise from acinar cells
Associated Syndromes
von Hippel-Lindau syndrome: Increased in frequency and often multiple
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Angiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Wang GX et al: Discrimination of serous cystadenoma from mucinous cystic neoplasm and branch duct intraductal papillary mucinous neoplasm in the pancreas with CT. Abdom Radiol (NY). 45(9):2772-8, 2020
Chen JY et al: Computed tomography and magnetic resonance imaging features of solid serous cystadenomas of the pancreas. Oncol Lett. 18(1):898-906, 2019
Giambelluca D et al: The honeycomb pattern of pancreatic serous cystadenoma. Abdom Radiol (NY). 44(3):1191-2, 2019
Park C et al: Growth rate of serous pancreatic neoplasms in vivo: a retrospective, observational study. Acta Radiol. 60(4):433-40, 2019
Bezerra ROF et al: Rare pancreatic masses: a pictorial review of radiological concepts. Clin Imaging. 50:314-23, 2018
Burk KS et al: Cystic pancreatic tumors. Magn Reson Imaging Clin N Am. 26(3):405-20, 2018
Chu LC et al: The many faces of pancreatic serous cystadenoma: radiologic and pathologic correlation. Diagn Interv Imaging. 98(3):191-202, 2017
Verde F et al: Calcified pancreatic and peripancreatic neoplasms: spectrum of pathologies. Abdom Radiol (NY). 42(11):2686-97, 2017
Chu LC et al: Characterization of pancreatic serous cystadenoma on dual-phase multidetector computed tomography. J Comput Assist Tomogr. 38(2):258-63, 2014
Raman SP et al: Endoscopic ultrasound and pancreatic applications: what the radiologist needs to know. Abdom Imaging. 38(6):1360-72, 2013
Zaheer A et al: Incidentally detected cystic lesions of the pancreas on CT: review of literature and management suggestions. Abdom Imaging. 38(2):331-41, 2013
Hayashi K et al: CT differentiation of solid serous cystadenoma vs endocrine tumor of the pancreas. Eur J Radiol. 81(3):e203-8, 2012
Khalpey Z et al: Serous cystadenoma causing the double duct sign. J Gastrointest Surg. 16(6):1282-3, 2012
Al-Haddad M et al: Diagnosis and treatment of cystic pancreatic tumors. Clin Gastroenterol Hepatol. 9(8):635-48, 2011
Khashab MA et al: Tumor size and location correlate with behavior of pancreatic serous cystic neoplasms. Am J Gastroenterol. 106(8):1521-6, 2011
Choi JY et al: Typical and atypical manifestations of serous cystadenoma of the pancreas: imaging findings with pathologic correlation. AJR Am J Roentgenol. 193(1):136-42, 2009
Wargo JA et al: Management of pancreatic serous cystadenomas. Adv Surg. 43:23-34, 2009
Kim SY et al: Macrocystic neoplasms of the pancreas: CT differentiation of serous oligocystic adenoma from mucinous cystadenoma and intraductal papillary mucinous tumor. AJR Am J Roentgenol. 187(5):1192-8, 2006
Cohen-Scali F et al: Discrimination of unilocular macrocystic serous cystadenoma from pancreatic pseudocyst and mucinous cystadenoma with CT: initial observations. Radiology. 228(3):727-33, 2003
Goldsmith JD: Cystic neoplasms of the pancreas. Am J Clin Pathol. 119 Suppl:S3-16, 2003
Sheth S et al: Imaging of uncommon tumors of the pancreas. Radiol Clin North Am. 40(6):1273-87, vi, 2002
Yeh HC et al: Microcystic features at US: a nonspecific sign for microcystic adenomas of the pancreas. Radiographics. 21(6):1455-61, 2001
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Synonyms
Glycogen-rich, microcystic, or macrocystic serous adenoma
Definitions
Benign pancreatic tumors lined by glycogen-rich cells that arise from acinar cells
Associated Syndromes
von Hippel-Lindau syndrome: Increased in frequency and often multiple
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Angiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Wang GX et al: Discrimination of serous cystadenoma from mucinous cystic neoplasm and branch duct intraductal papillary mucinous neoplasm in the pancreas with CT. Abdom Radiol (NY). 45(9):2772-8, 2020
Chen JY et al: Computed tomography and magnetic resonance imaging features of solid serous cystadenomas of the pancreas. Oncol Lett. 18(1):898-906, 2019
Giambelluca D et al: The honeycomb pattern of pancreatic serous cystadenoma. Abdom Radiol (NY). 44(3):1191-2, 2019
Park C et al: Growth rate of serous pancreatic neoplasms in vivo: a retrospective, observational study. Acta Radiol. 60(4):433-40, 2019
Bezerra ROF et al: Rare pancreatic masses: a pictorial review of radiological concepts. Clin Imaging. 50:314-23, 2018
Burk KS et al: Cystic pancreatic tumors. Magn Reson Imaging Clin N Am. 26(3):405-20, 2018
Chu LC et al: The many faces of pancreatic serous cystadenoma: radiologic and pathologic correlation. Diagn Interv Imaging. 98(3):191-202, 2017
Verde F et al: Calcified pancreatic and peripancreatic neoplasms: spectrum of pathologies. Abdom Radiol (NY). 42(11):2686-97, 2017
Chu LC et al: Characterization of pancreatic serous cystadenoma on dual-phase multidetector computed tomography. J Comput Assist Tomogr. 38(2):258-63, 2014
Raman SP et al: Endoscopic ultrasound and pancreatic applications: what the radiologist needs to know. Abdom Imaging. 38(6):1360-72, 2013
Zaheer A et al: Incidentally detected cystic lesions of the pancreas on CT: review of literature and management suggestions. Abdom Imaging. 38(2):331-41, 2013
Hayashi K et al: CT differentiation of solid serous cystadenoma vs endocrine tumor of the pancreas. Eur J Radiol. 81(3):e203-8, 2012
Khalpey Z et al: Serous cystadenoma causing the double duct sign. J Gastrointest Surg. 16(6):1282-3, 2012
Al-Haddad M et al: Diagnosis and treatment of cystic pancreatic tumors. Clin Gastroenterol Hepatol. 9(8):635-48, 2011
Khashab MA et al: Tumor size and location correlate with behavior of pancreatic serous cystic neoplasms. Am J Gastroenterol. 106(8):1521-6, 2011
Choi JY et al: Typical and atypical manifestations of serous cystadenoma of the pancreas: imaging findings with pathologic correlation. AJR Am J Roentgenol. 193(1):136-42, 2009
Wargo JA et al: Management of pancreatic serous cystadenomas. Adv Surg. 43:23-34, 2009
Kim SY et al: Macrocystic neoplasms of the pancreas: CT differentiation of serous oligocystic adenoma from mucinous cystadenoma and intraductal papillary mucinous tumor. AJR Am J Roentgenol. 187(5):1192-8, 2006
Cohen-Scali F et al: Discrimination of unilocular macrocystic serous cystadenoma from pancreatic pseudocyst and mucinous cystadenoma with CT: initial observations. Radiology. 228(3):727-33, 2003
Goldsmith JD: Cystic neoplasms of the pancreas. Am J Clin Pathol. 119 Suppl:S3-16, 2003
Sheth S et al: Imaging of uncommon tumors of the pancreas. Radiol Clin North Am. 40(6):1273-87, vi, 2002
Yeh HC et al: Microcystic features at US: a nonspecific sign for microcystic adenomas of the pancreas. Radiographics. 21(6):1455-61, 2001
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