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Papillary Tumor of the Pineal Region
Karen L. Salzman, MD; John H. Rees, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Papillary tumor of pineal region (PTPR)

            IMAGING

            • General Features

              • Imaging Recommendations

                • MR Findings

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      • Staging, Grading, & Classification

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    Selected References

                                    1. Edson MA et al: Outcomes after surgery and radiotherapy for papillary tumor of the pineal region. World Neurosurg. ePub, 2015
                                    2. Heim S et al: Increased mitotic and proliferative activity are associated with worse prognosis in papillary tumors of the pineal region. Am J Surg Pathol. 38(1):106-10, 2014
                                    3. Cohen AL et al: Bevacizumab is effective for recurrent papillary tumor of the pineal region: first report. Case Rep Oncol. 6(2):434-40, 2013
                                    4. Fauchon F et al: Role of surgery, radiotherapy and chemotherapy in papillary tumors of the pineal region: a multicenter study. J Neurooncol. 112(2):223-31, 2013
                                    5. Patel SK et al: Complete regression of papillary tumor of the pineal region after radiation therapy: case report and review of the literature. J Neurooncol. 107(2):427-34, 2012
                                    6. Cerase A et al: Neuroradiological follow-up of the growth of papillary tumor of the pineal region: a case report. J Neurooncol. 95(3):433-5, 2009
                                    7. Sato TS et al: Papillary tumor of the pineal region: report of a rapidly progressive tumor with possible multicentric origin. Pediatr Radiol. 39(2):188-90, 2009
                                    8. Boco T et al: Papillary tumor of the pineal region. Neuropathology. 28(1):87-92, 2008
                                    9. Chang AH et al: MR imaging of papillary tumor of the pineal region. AJNR Am J Neuroradiol. 29(1):187-9, 2008
                                    10. Fèvre-Montange M et al: Bcl-2 expression in a papillary tumor of the pineal region. Neuropathology. 28(6):660-3, 2008
                                    11. Lehman NL: Central nervous system tumors with ependymal features: a broadened spectrum of primarily ependymal differentiation? J Neuropathol Exp Neurol. 67(3):177-88, 2008
                                    12. Louis DN et al: The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007 Aug;114(2):97-109. Epub 2007 Jul 6. Review. Erratum in: Acta Neuropathol. 114(5):547, 2007
                                    13. Roncaroli F et al: Papillary tumor of the pineal region and spindle cell oncocytoma of the pituitary: new tumor entities in the 2007 WHO Classification. Brain Pathol. 17(3):314-8, 2007
                                    14. Fèvre-Montange M et al: Prognosis and histopathologic features in papillary tumors of the pineal region: a retrospective multicenter study of 31 cases. J Neuropathol Exp Neurol. 65(10):1004-11, 2006
                                    15. Hasselblatt M et al: Immunohistochemical profile and chromosomal imbalances in papillary tumours of the pineal region. Neuropathol Appl Neurobiol. 32(3):278-83, 2006
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Pathology

                                            • Clinical Issues

                                              TERMINOLOGY

                                              • Abbreviations

                                                • Papillary tumor of pineal region (PTPR)

                                              IMAGING

                                              • General Features

                                                • Imaging Recommendations

                                                  • MR Findings

                                                    DIFFERENTIAL DIAGNOSIS

                                                      PATHOLOGY

                                                      • General Features

                                                        • Staging, Grading, & Classification

                                                          • Gross Pathologic & Surgical Features

                                                            • Microscopic Features

                                                              CLINICAL ISSUES

                                                              • Presentation

                                                                • Demographics

                                                                  • Natural History & Prognosis

                                                                    • Treatment

                                                                      Selected References

                                                                      1. Edson MA et al: Outcomes after surgery and radiotherapy for papillary tumor of the pineal region. World Neurosurg. ePub, 2015
                                                                      2. Heim S et al: Increased mitotic and proliferative activity are associated with worse prognosis in papillary tumors of the pineal region. Am J Surg Pathol. 38(1):106-10, 2014
                                                                      3. Cohen AL et al: Bevacizumab is effective for recurrent papillary tumor of the pineal region: first report. Case Rep Oncol. 6(2):434-40, 2013
                                                                      4. Fauchon F et al: Role of surgery, radiotherapy and chemotherapy in papillary tumors of the pineal region: a multicenter study. J Neurooncol. 112(2):223-31, 2013
                                                                      5. Patel SK et al: Complete regression of papillary tumor of the pineal region after radiation therapy: case report and review of the literature. J Neurooncol. 107(2):427-34, 2012
                                                                      6. Cerase A et al: Neuroradiological follow-up of the growth of papillary tumor of the pineal region: a case report. J Neurooncol. 95(3):433-5, 2009
                                                                      7. Sato TS et al: Papillary tumor of the pineal region: report of a rapidly progressive tumor with possible multicentric origin. Pediatr Radiol. 39(2):188-90, 2009
                                                                      8. Boco T et al: Papillary tumor of the pineal region. Neuropathology. 28(1):87-92, 2008
                                                                      9. Chang AH et al: MR imaging of papillary tumor of the pineal region. AJNR Am J Neuroradiol. 29(1):187-9, 2008
                                                                      10. Fèvre-Montange M et al: Bcl-2 expression in a papillary tumor of the pineal region. Neuropathology. 28(6):660-3, 2008
                                                                      11. Lehman NL: Central nervous system tumors with ependymal features: a broadened spectrum of primarily ependymal differentiation? J Neuropathol Exp Neurol. 67(3):177-88, 2008
                                                                      12. Louis DN et al: The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007 Aug;114(2):97-109. Epub 2007 Jul 6. Review. Erratum in: Acta Neuropathol. 114(5):547, 2007
                                                                      13. Roncaroli F et al: Papillary tumor of the pineal region and spindle cell oncocytoma of the pituitary: new tumor entities in the 2007 WHO Classification. Brain Pathol. 17(3):314-8, 2007
                                                                      14. Fèvre-Montange M et al: Prognosis and histopathologic features in papillary tumors of the pineal region: a retrospective multicenter study of 31 cases. J Neuropathol Exp Neurol. 65(10):1004-11, 2006
                                                                      15. Hasselblatt M et al: Immunohistochemical profile and chromosomal imbalances in papillary tumours of the pineal region. Neuropathol Appl Neurobiol. 32(3):278-83, 2006