link
Bookmarks
Parathyroid Adenoma
Paige Bennett, MD; T. Alex McKnight, MD
To access 4,300 diagnoses written by the world's leading experts in radiology, please log in or subscribe.Log inSubscribe
0
5
1
0

KEY FACTS

  • Terminology

    • Pathology

      • Diagnostic Checklist

        TERMINOLOGY

        • Definitions

          • Parathyroid adenoma
            • Most common cause of primary hyperparathyroidism
              • Hypercalcemia due to increased production of parathyroid hormone (PTH) by parathyroid gland(s)
            • Enlarged parathyroid gland with normal cellular structure
            • May be posterior to thyroid gland or ectopic

        IMAGING

        • Nuclear Medicine Findings

          • Imaging Recommendations

            DIFFERENTIAL DIAGNOSIS

              PATHOLOGY

              • General Features

                • Gross Pathologic & Surgical Features

                  • Microscopic Features

                    • Anatomic Location of Parathyroid Glands

                      CLINICAL ISSUES

                      • Presentation

                        • Demographics

                          • Treatment

                            DIAGNOSTIC CHECKLIST

                            • Image Interpretation Pearls

                              Selected References

                              1. Schenk WG 3rd et al: Surgeon-performed ultrasound for primary hyperparathyroidism. Am Surg. 79(7):681-5, 2013
                              2. Greenspan BS et al: SNM practice guideline for parathyroid scintigraphy 4.0. J Nucl Med Technol. 40(2):111-8, 2012
                              3. Mohebati A et al: Imaging techniques in parathyroid surgery for primary hyperparathyroidism. Am J Otolaryngol. 33(4):457-68, 2012
                              4. Carlson D: Parathyroid pathology: hyperparathyroidism and parathyroid tumors. Arch Pathol Lab Med. 134(11):1639-44, 2010
                              5. Baliski CR et al: Selective unilateral parathyroid exploration: an effective treatment for primary hyperparathyroidism. Am J Surg. 189(5):596-600; discussion 600, 2005
                              6. Cohen MS et al: Outpatient minimally invasive parathyroidectomy using local/regional anesthesia: a safe and effective operative approach for selected patients. Surgery. 138(4):681-7; discussion 687-9, 2005
                              7. Gilat H et al: Minimally invasive procedure for resection of a parathyroid adenoma: the role of preoperative high-resolution ultrasonography. J Clin Ultrasound. 33(6):283-7, 2005
                              8. Kleinpeter KP et al: Is parathyroid carcinoma indeed a lethal disease? Ann Surg Oncol. 12(3):260-6, 2005
                              9. Kraas J et al: The scintigraphic appearance of subcapsular parathyroid adenomas. Clin Nucl Med. 30(4):213-7, 2005
                              10. Mehta NY et al: Relationship of technetium Tc 99m sestamibi scans to histopathological features of hyperfunctioning parathyroid tissue. Arch Otolaryngol Head Neck Surg. 131(6):493-8, 2005
                              11. Palestro CJ et al: Radionuclide imaging of the parathyroid glands. Semin Nucl Med. 35(4):266-76, 2005
                              12. Shi H et al: Parathyroid and bone scintigraphy in hyperparathyroidism. Clin Nucl Med. 30(11):769-70, 2005
                              13. Clark P et al: Providing optimal preoperative localization for recurrent parathyroid carcinoma: a combined parathyroid scintigraphy and computed tomography approach. Clin Nucl Med. 29(11):681-4, 2004
                              14. Smith JR et al: Radionuclide imaging of the parathyroid glands: patterns, pearls, and pitfalls. Radiographics. 24(4):1101-15, 2004
                              15. Clark PB et al: Enhanced scintigraphic protocol required for optimal preoperative localization before targeted minimally invasive parathyroidectomy. Clin Nucl Med. 28(12):955-60, 2003
                              Related Anatomy
                              Loading...
                              Related Differential Diagnoses
                              Loading...
                              References
                              Tables

                              Tables

                              KEY FACTS

                              • Terminology

                                • Pathology

                                  • Diagnostic Checklist

                                    TERMINOLOGY

                                    • Definitions

                                      • Parathyroid adenoma
                                        • Most common cause of primary hyperparathyroidism
                                          • Hypercalcemia due to increased production of parathyroid hormone (PTH) by parathyroid gland(s)
                                        • Enlarged parathyroid gland with normal cellular structure
                                        • May be posterior to thyroid gland or ectopic

                                    IMAGING

                                    • Nuclear Medicine Findings

                                      • Imaging Recommendations

                                        DIFFERENTIAL DIAGNOSIS

                                          PATHOLOGY

                                          • General Features

                                            • Gross Pathologic & Surgical Features

                                              • Microscopic Features

                                                • Anatomic Location of Parathyroid Glands

                                                  CLINICAL ISSUES

                                                  • Presentation

                                                    • Demographics

                                                      • Treatment

                                                        DIAGNOSTIC CHECKLIST

                                                        • Image Interpretation Pearls

                                                          Selected References

                                                          1. Schenk WG 3rd et al: Surgeon-performed ultrasound for primary hyperparathyroidism. Am Surg. 79(7):681-5, 2013
                                                          2. Greenspan BS et al: SNM practice guideline for parathyroid scintigraphy 4.0. J Nucl Med Technol. 40(2):111-8, 2012
                                                          3. Mohebati A et al: Imaging techniques in parathyroid surgery for primary hyperparathyroidism. Am J Otolaryngol. 33(4):457-68, 2012
                                                          4. Carlson D: Parathyroid pathology: hyperparathyroidism and parathyroid tumors. Arch Pathol Lab Med. 134(11):1639-44, 2010
                                                          5. Baliski CR et al: Selective unilateral parathyroid exploration: an effective treatment for primary hyperparathyroidism. Am J Surg. 189(5):596-600; discussion 600, 2005
                                                          6. Cohen MS et al: Outpatient minimally invasive parathyroidectomy using local/regional anesthesia: a safe and effective operative approach for selected patients. Surgery. 138(4):681-7; discussion 687-9, 2005
                                                          7. Gilat H et al: Minimally invasive procedure for resection of a parathyroid adenoma: the role of preoperative high-resolution ultrasonography. J Clin Ultrasound. 33(6):283-7, 2005
                                                          8. Kleinpeter KP et al: Is parathyroid carcinoma indeed a lethal disease? Ann Surg Oncol. 12(3):260-6, 2005
                                                          9. Kraas J et al: The scintigraphic appearance of subcapsular parathyroid adenomas. Clin Nucl Med. 30(4):213-7, 2005
                                                          10. Mehta NY et al: Relationship of technetium Tc 99m sestamibi scans to histopathological features of hyperfunctioning parathyroid tissue. Arch Otolaryngol Head Neck Surg. 131(6):493-8, 2005
                                                          11. Palestro CJ et al: Radionuclide imaging of the parathyroid glands. Semin Nucl Med. 35(4):266-76, 2005
                                                          12. Shi H et al: Parathyroid and bone scintigraphy in hyperparathyroidism. Clin Nucl Med. 30(11):769-70, 2005
                                                          13. Clark P et al: Providing optimal preoperative localization for recurrent parathyroid carcinoma: a combined parathyroid scintigraphy and computed tomography approach. Clin Nucl Med. 29(11):681-4, 2004
                                                          14. Smith JR et al: Radionuclide imaging of the parathyroid glands: patterns, pearls, and pitfalls. Radiographics. 24(4):1101-15, 2004
                                                          15. Clark PB et al: Enhanced scintigraphic protocol required for optimal preoperative localization before targeted minimally invasive parathyroidectomy. Clin Nucl Med. 28(12):955-60, 2003