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Parathyroid Carcinoma
Eunice Y. L. Dai, MBBS, FRCR; Yolanda Y. P. Lee, MBChB, FRCR; Anil T. Ahuja, MD, FRCR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Diagnostic Checklist

          TERMINOLOGY

          • Abbreviations

            • Parathyroid carcinoma (PTCa)
          • Definitions

            • Low-grade malignancy arising from parathyroid gland

          IMAGING

          • General Features

            • Ultrasonographic Findings

              • CT Findings

                • Nuclear Medicine Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Staging, Grading, & Classification

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Image Interpretation Pearls

                                    • Reporting Tips

                                      Selected References

                                      1. Christakis I et al: The diagnostic accuracy of neck ultrasound, 4D-Computed tomographyand sestamibi imaging in parathyroid carcinoma. Eur J Radiol. 95:82-88, 2017
                                      2. Nam M et al: Differentiation of parathyroid carcinoma and adenoma by preoperative ultrasonography. Acta Radiol. 58(6):670-675, 2017
                                      3. Halenka M et al: Four ultrasound and clinical pictures of parathyroid carcinoma. Case Rep Endocrinol. 2012:363690, 2012
                                      4. Digonnet A et al: Parathyroid carcinoma: a review with three illustrative cases. J Cancer. 2:532-7, 2011
                                      5. Owen RP et al: Parathyroid carcinoma: a review. Head Neck. 33(3):429-36, 2011
                                      6. Sidhu PS et al: Ultrasound features of malignancy in the preoperative diagnosis of parathyroid cancer: a retrospective analysis of parathyroid tumours larger than 15 mm. Eur Radiol. 21(9):1865-73, 2011
                                      7. Dudney WC et al: Parathyroid carcinoma. Otolaryngol Clin North Am. 43(2):441-53, xi, 2010
                                      8. Givi B et al: Parathyroid carcinoma. Clin Oncol (R Coll Radiol). 22(6):498-507, 2010
                                      9. Lee YS et al: Parathyroid carcinoma: a 16-year experience in a single institution. Endocr J. 57(6):493-7, 2010
                                      10. Okamoto T et al: Parathyroid carcinoma: etiology, diagnosis, and treatment. World J Surg. 33(11):2343-54, 2009
                                      11. Fakhran S et al: Parathyroid imaging. Neuroimaging Clin N Am. 18(3):537-49, ix, 2008
                                      12. Hara H et al: Ultrasonographic features of parathyroid carcinoma. Endocr J. 48(2):213-7, 2001
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Top Differential Diagnoses

                                            • Diagnostic Checklist

                                              TERMINOLOGY

                                              • Abbreviations

                                                • Parathyroid carcinoma (PTCa)
                                              • Definitions

                                                • Low-grade malignancy arising from parathyroid gland

                                              IMAGING

                                              • General Features

                                                • Ultrasonographic Findings

                                                  • CT Findings

                                                    • Nuclear Medicine Findings

                                                      • Imaging Recommendations

                                                        DIFFERENTIAL DIAGNOSIS

                                                          PATHOLOGY

                                                          • General Features

                                                            • Staging, Grading, & Classification

                                                              CLINICAL ISSUES

                                                              • Presentation

                                                                • Demographics

                                                                  • Natural History & Prognosis

                                                                    • Treatment

                                                                      DIAGNOSTIC CHECKLIST

                                                                      • Image Interpretation Pearls

                                                                        • Reporting Tips

                                                                          Selected References

                                                                          1. Christakis I et al: The diagnostic accuracy of neck ultrasound, 4D-Computed tomographyand sestamibi imaging in parathyroid carcinoma. Eur J Radiol. 95:82-88, 2017
                                                                          2. Nam M et al: Differentiation of parathyroid carcinoma and adenoma by preoperative ultrasonography. Acta Radiol. 58(6):670-675, 2017
                                                                          3. Halenka M et al: Four ultrasound and clinical pictures of parathyroid carcinoma. Case Rep Endocrinol. 2012:363690, 2012
                                                                          4. Digonnet A et al: Parathyroid carcinoma: a review with three illustrative cases. J Cancer. 2:532-7, 2011
                                                                          5. Owen RP et al: Parathyroid carcinoma: a review. Head Neck. 33(3):429-36, 2011
                                                                          6. Sidhu PS et al: Ultrasound features of malignancy in the preoperative diagnosis of parathyroid cancer: a retrospective analysis of parathyroid tumours larger than 15 mm. Eur Radiol. 21(9):1865-73, 2011
                                                                          7. Dudney WC et al: Parathyroid carcinoma. Otolaryngol Clin North Am. 43(2):441-53, xi, 2010
                                                                          8. Givi B et al: Parathyroid carcinoma. Clin Oncol (R Coll Radiol). 22(6):498-507, 2010
                                                                          9. Lee YS et al: Parathyroid carcinoma: a 16-year experience in a single institution. Endocr J. 57(6):493-7, 2010
                                                                          10. Okamoto T et al: Parathyroid carcinoma: etiology, diagnosis, and treatment. World J Surg. 33(11):2343-54, 2009
                                                                          11. Fakhran S et al: Parathyroid imaging. Neuroimaging Clin N Am. 18(3):537-49, ix, 2008
                                                                          12. Hara H et al: Ultrasonographic features of parathyroid carcinoma. Endocr J. 48(2):213-7, 2001