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Parotid and Salivary Gland Carcinoma
Amanda Jo Lott Marcellino, MD; Paige Bennett, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Diagnostic Checklist

        TERMINOLOGY

        • Definitions

          • Tumors of parotid and submandibular glands (as well as minor salivary tissue) include
            • Parotid carcinoma (most common site of salivary gland cancer)
            • Benign mixed tumors or pleomorphic adenoma
            • Warthin tumor
            • Primary lymphoma

        IMAGING

        • F-18 FDG PET/CT Findings

          • CT Findings

            • MR Findings

              DIFFERENTIAL DIAGNOSIS

                PATHOLOGY

                • General Features

                  • Staging, Grading, & Classification

                    • Gross Pathologic & Surgical Features

                      CLINICAL ISSUES

                      • Presentation

                        • Treatment

                          DIAGNOSTIC CHECKLIST

                          • Image Interpretation Pearls

                            Selected References

                            1. Panwar A et al: Cancers of major salivary glands. Surg Oncol Clin N Am. 24(3):615-633, 2015
                            2. Uchida Y et al: Diagnostic value of FDG PET and salivary gland scintigraphy for parotid tumors. Clin Nucl Med. 30(3):170-6, 2005
                            3. Witt RL et al: Etiology and management of recurrent parotid pleomorphic adenoma. Laryngoscope. 125(4):888-93, 2014
                            4. Johnson, JT. Bailey's Head and Neck Surgery Otolaryngology. 5th edition. 1760-1775, 2014
                            5. Peter Klussmann J et al: High risk for bilateral Warthin tumor in heavy smokers--review of 185 cases. Acta Otolaryngol. 126(11):1213-7, 2006
                            6. Horiuchi M et al: Four cases of Warthin's tumor of the parotid gland detected with FDG PET. Ann Nucl Med. 12(1):47-50, 1998
                            7. Matsuda M et al: Positron emission tomographic imaging of pleomorphic adenoma in the parotid gland. Acta Otolaryngol Suppl. 538:214-20, 1998
                            8. Okamura T et al: Fluorine-18 fluorodeoxyglucose positron emission tomography imaging of parotid mass lesions. Acta Otolaryngol Suppl. 538:209-13, 1998
                            9. Keyes JW Jr et al: Salivary gland tumors: pretherapy evaluation with PET. Radiology. 192(1):99-102, 1994
                            Related Anatomy
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                            Related Differential Diagnoses
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                            References
                            Tables

                            Tables

                            KEY FACTS

                            • Terminology

                              • Imaging

                                • Diagnostic Checklist

                                  TERMINOLOGY

                                  • Definitions

                                    • Tumors of parotid and submandibular glands (as well as minor salivary tissue) include
                                      • Parotid carcinoma (most common site of salivary gland cancer)
                                      • Benign mixed tumors or pleomorphic adenoma
                                      • Warthin tumor
                                      • Primary lymphoma

                                  IMAGING

                                  • F-18 FDG PET/CT Findings

                                    • CT Findings

                                      • MR Findings

                                        DIFFERENTIAL DIAGNOSIS

                                          PATHOLOGY

                                          • General Features

                                            • Staging, Grading, & Classification

                                              • Gross Pathologic & Surgical Features

                                                CLINICAL ISSUES

                                                • Presentation

                                                  • Treatment

                                                    DIAGNOSTIC CHECKLIST

                                                    • Image Interpretation Pearls

                                                      Selected References

                                                      1. Panwar A et al: Cancers of major salivary glands. Surg Oncol Clin N Am. 24(3):615-633, 2015
                                                      2. Uchida Y et al: Diagnostic value of FDG PET and salivary gland scintigraphy for parotid tumors. Clin Nucl Med. 30(3):170-6, 2005
                                                      3. Witt RL et al: Etiology and management of recurrent parotid pleomorphic adenoma. Laryngoscope. 125(4):888-93, 2014
                                                      4. Johnson, JT. Bailey's Head and Neck Surgery Otolaryngology. 5th edition. 1760-1775, 2014
                                                      5. Peter Klussmann J et al: High risk for bilateral Warthin tumor in heavy smokers--review of 185 cases. Acta Otolaryngol. 126(11):1213-7, 2006
                                                      6. Horiuchi M et al: Four cases of Warthin's tumor of the parotid gland detected with FDG PET. Ann Nucl Med. 12(1):47-50, 1998
                                                      7. Matsuda M et al: Positron emission tomographic imaging of pleomorphic adenoma in the parotid gland. Acta Otolaryngol Suppl. 538:214-20, 1998
                                                      8. Okamura T et al: Fluorine-18 fluorodeoxyglucose positron emission tomography imaging of parotid mass lesions. Acta Otolaryngol Suppl. 538:209-13, 1998
                                                      9. Keyes JW Jr et al: Salivary gland tumors: pretherapy evaluation with PET. Radiology. 192(1):99-102, 1994