Recent reports of associated endocrine abnormalities (hypopituitarism, ectopic thyroid)
Kasselbach-Merrit syndrome
Hemangioma associated with thrombocytopenia
Platelet consumption from large hemangiomas
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Kim KH et al: Comparison of efficacy and safety between propranolol and steroid for infantile hemangioma: a randomized clinical trial. JAMA Dermatol. 153(6):529-36, 2017
Rotter A et al: Ultrasonography as an objective tool for assessment of infantile hemangioma treatment with propranolol. Int J Dermatol. 56(2):190-4, 2017
Weber FC et al: Role of imaging in the diagnosis of parotid infantile hemangiomas. Int J Pediatr Otorhinolaryngol. 102:61-6, 2017
Bauman NM et al: Propranolol vs prednisolone for symptomatic proliferating infantile hemangiomas: a randomized clinical trial. JAMA Otolaryngol Head Neck Surg. 140(4):323-30, 2014
Shi H et al: Ultrasound in assessing the efficacy of propranolol therapy for infantile hemangiomas. Ultrasound Med Biol. 40(11):2622-9, 2014
Dubois J et al: Vascular anomalies: what a radiologist needs to know. Pediatr Radiol. 40(6):895-905, 2010
Holmes WJ et al: Propranolol as first-line treatment for infantile hemangiomas. Plast Reconstr Surg. 125(1):420-1, 2010
Maturo S et al: Initial experience using propranolol as the sole treatment for infantile airway hemangiomas. Int J Pediatr Otorhinolaryngol. 74(3):323-5, 2010
Mistry N et al: Use of propranolol to treat multicentric airway haemangioma. J Laryngol Otol. 124(12):1329-32, 2010
Sinno H et al: Management of infantile parotid gland hemangiomas: a 40-year experience. Plast Reconstr Surg. 125(1):265-73, 2010
Storch CH et al: Propranolol for infantile haemangiomas: insights into the molecular mechanisms of action. Br J Dermatol. 163(2):269-74, 2010
Metry D et al: Consensus statement on diagnostic criteria for PHACE syndrome. Pediatrics. 124(5):1447-56, 2009
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Abbreviations
Infantile hemangioma (IH)
Synonyms
Hemangioma of infancy
Capillary hemangioma (older term)
Definitions
Benign vascular neoplasm of proliferating endothelial cells
Not vascular malformation
Associated Syndromes
PHACES association
Posterior fossa and supratentorial brain malformations (Dandy-Walker malformation/variant, migrational anomaly)
Recent reports of associated endocrine abnormalities (hypopituitarism, ectopic thyroid)
Kasselbach-Merrit syndrome
Hemangioma associated with thrombocytopenia
Platelet consumption from large hemangiomas
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Kim KH et al: Comparison of efficacy and safety between propranolol and steroid for infantile hemangioma: a randomized clinical trial. JAMA Dermatol. 153(6):529-36, 2017
Rotter A et al: Ultrasonography as an objective tool for assessment of infantile hemangioma treatment with propranolol. Int J Dermatol. 56(2):190-4, 2017
Weber FC et al: Role of imaging in the diagnosis of parotid infantile hemangiomas. Int J Pediatr Otorhinolaryngol. 102:61-6, 2017
Bauman NM et al: Propranolol vs prednisolone for symptomatic proliferating infantile hemangiomas: a randomized clinical trial. JAMA Otolaryngol Head Neck Surg. 140(4):323-30, 2014
Shi H et al: Ultrasound in assessing the efficacy of propranolol therapy for infantile hemangiomas. Ultrasound Med Biol. 40(11):2622-9, 2014
Dubois J et al: Vascular anomalies: what a radiologist needs to know. Pediatr Radiol. 40(6):895-905, 2010
Holmes WJ et al: Propranolol as first-line treatment for infantile hemangiomas. Plast Reconstr Surg. 125(1):420-1, 2010
Maturo S et al: Initial experience using propranolol as the sole treatment for infantile airway hemangiomas. Int J Pediatr Otorhinolaryngol. 74(3):323-5, 2010
Mistry N et al: Use of propranolol to treat multicentric airway haemangioma. J Laryngol Otol. 124(12):1329-32, 2010
Sinno H et al: Management of infantile parotid gland hemangiomas: a 40-year experience. Plast Reconstr Surg. 125(1):265-73, 2010
Storch CH et al: Propranolol for infantile haemangiomas: insights into the molecular mechanisms of action. Br J Dermatol. 163(2):269-74, 2010
Metry D et al: Consensus statement on diagnostic criteria for PHACE syndrome. Pediatrics. 124(5):1447-56, 2009
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