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Head and Neck
Diagnosis
Parotid Space
Benign Tumors
Parotid Schwannoma
Parotid Schwannoma
Lisa J. Koenig, BChD, DDS, MS; Hilda E. Stambuk, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Synonyms

              • Facial neurilemmoma, intraparotid neurilemmoma

            • Definitions

              • Benign nerve sheath neoplasm from Schwann cells of intraparotid facial nerve (CNVII)

            IMAGING

            • General Features

              • Imaging Recommendations

                • CT Findings

                  • MR Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Behera P et al: Aspiration cytology of facial nerve schwannoma of parotid gland: a rare diagnosis. Cytopathology. 33(5):618-21, 2022
                                          2. Jiang JY et al: A giant schwannoma extending from medial portion of middle cranial fossa to parapharyngeal space and deep parotid space. Ear Nose Throat J. ePub, 2022
                                          3. Malić M et al: Multicentric intra/extracranial cystic facial nerve schwannoma: case report and review of literature. Indian J Otolaryngol Head Neck Surg. 74(Suppl 3):3872-6, 2022
                                          4. Shamim M et al: Giant facial nerve schwannoma with extra-temporal involvement: a series of two cases. Indian J Otolaryngol Head Neck Surg. 74(Suppl 3):4399-404, 2022
                                          5. Singh AK et al: Systematic review of intra parotid facial nerve schwannoma and a case report. Indian J Otolaryngol Head Neck Surg. 74(Suppl 3):6268-84, 2022
                                          6. Bartindale M et al: Facial schwannoma management outcomes: a systematic review of the literature. Otolaryngol Head Neck Surg. 163(2):293-301, 2020
                                          7. Seo BF et al: Intraparotid facial nerve schwannomas. Arch Craniofac Surg. 20(1):71-4, 2019
                                          8. Carlson ML et al: Facial nerve schwannomas: review of 80 cases over 25 years at Mayo Clinic. Mayo Clin Proc. 91(11):1563-76, 2016
                                          9. Zhang GZ et al: Clinical retrospective analysis of 9 cases of intraparotid facial nerve schwannoma. J Oral Maxillofac Surg. pii: S0278-2391(16)00165-8, 2016
                                          10. Bartindale M et al: The natural history of facial schwannomas: a meta-analysis of case series. J Neurol Surg B Skull Base. 80(5):458-68, 2019
                                          11. McCarthy WA et al: Intraparotid schwannoma. Arch Pathol Lab Med. 138(7):982-5, 2014
                                          12. Nader ME et al: Facial nerve paralysis due to a pleomorphic adenoma with the imaging characteristics of a facial nerve schwannoma. J Neurol Surg Rep. 75(1):e84-8, 2014
                                          13. De Ceulaer J et al: Intraparotid facial nerve schwannoma: case report and literature review. B-ENT. 8(3):225-8, 2012
                                          14. Gross BC et al: The intraparotid facial nerve schwannoma: a diagnostic and management conundrum. Am J Otolaryngol. 33(5):497-504, 2012
                                          15. Ma Q et al: Diagnosis and management of intraparotid facial nerve schwannoma. J Craniomaxillofac Surg. 38(4):271-3, 2010
                                          16. Alicandri-Ciufelli M et al: Critical literature review on the management of intraparotid facial nerve schwannoma and proposed decision-making algorithm. Eur Arch Otorhinolaryngol. 266(4):475-9, 2009
                                          17. Guzzo M et al: Schwannoma in the parotid gland. Experience at our institute and review of the literature. Tumori. 95(6):846-51, 2009
                                          18. Tanna N et al: Intraparotid facial nerve schwannoma: clinician beware. Ear Nose Throat J. 88(8):E18-20, 2009
                                          19. Mehta RP et al: Intraoperative diagnosis of facial nerve schwannoma at parotidectomy. Am J Otolaryngol. 29(2):126-9, 2008
                                          20. Salemis NS et al: Large intraparotid facial nerve schwannoma: case report and review of the literature. Int J Oral Maxillofac Surg. 37(7):679-81, 2008
                                          21. Marchioni D et al: Intraparotid facial nerve schwannoma: literature review and classification proposal. J Laryngol Otol. 121(8):707-12, 2007
                                          22. Ciko Z: [Current treatment of acute leukemias.] Vojnosanit Pregl. 26(11):563-6, 1969
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    TERMINOLOGY

                                                    • Synonyms

                                                      • Facial neurilemmoma, intraparotid neurilemmoma

                                                    • Definitions

                                                      • Benign nerve sheath neoplasm from Schwann cells of intraparotid facial nerve (CNVII)

                                                    IMAGING

                                                    • General Features

                                                      • Imaging Recommendations

                                                        • CT Findings

                                                          • MR Findings

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Staging, Grading, & Classification

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Behera P et al: Aspiration cytology of facial nerve schwannoma of parotid gland: a rare diagnosis. Cytopathology. 33(5):618-21, 2022
                                                                                  2. Jiang JY et al: A giant schwannoma extending from medial portion of middle cranial fossa to parapharyngeal space and deep parotid space. Ear Nose Throat J. ePub, 2022
                                                                                  3. Malić M et al: Multicentric intra/extracranial cystic facial nerve schwannoma: case report and review of literature. Indian J Otolaryngol Head Neck Surg. 74(Suppl 3):3872-6, 2022
                                                                                  4. Shamim M et al: Giant facial nerve schwannoma with extra-temporal involvement: a series of two cases. Indian J Otolaryngol Head Neck Surg. 74(Suppl 3):4399-404, 2022
                                                                                  5. Singh AK et al: Systematic review of intra parotid facial nerve schwannoma and a case report. Indian J Otolaryngol Head Neck Surg. 74(Suppl 3):6268-84, 2022
                                                                                  6. Bartindale M et al: Facial schwannoma management outcomes: a systematic review of the literature. Otolaryngol Head Neck Surg. 163(2):293-301, 2020
                                                                                  7. Seo BF et al: Intraparotid facial nerve schwannomas. Arch Craniofac Surg. 20(1):71-4, 2019
                                                                                  8. Carlson ML et al: Facial nerve schwannomas: review of 80 cases over 25 years at Mayo Clinic. Mayo Clin Proc. 91(11):1563-76, 2016
                                                                                  9. Zhang GZ et al: Clinical retrospective analysis of 9 cases of intraparotid facial nerve schwannoma. J Oral Maxillofac Surg. pii: S0278-2391(16)00165-8, 2016
                                                                                  10. Bartindale M et al: The natural history of facial schwannomas: a meta-analysis of case series. J Neurol Surg B Skull Base. 80(5):458-68, 2019
                                                                                  11. McCarthy WA et al: Intraparotid schwannoma. Arch Pathol Lab Med. 138(7):982-5, 2014
                                                                                  12. Nader ME et al: Facial nerve paralysis due to a pleomorphic adenoma with the imaging characteristics of a facial nerve schwannoma. J Neurol Surg Rep. 75(1):e84-8, 2014
                                                                                  13. De Ceulaer J et al: Intraparotid facial nerve schwannoma: case report and literature review. B-ENT. 8(3):225-8, 2012
                                                                                  14. Gross BC et al: The intraparotid facial nerve schwannoma: a diagnostic and management conundrum. Am J Otolaryngol. 33(5):497-504, 2012
                                                                                  15. Ma Q et al: Diagnosis and management of intraparotid facial nerve schwannoma. J Craniomaxillofac Surg. 38(4):271-3, 2010
                                                                                  16. Alicandri-Ciufelli M et al: Critical literature review on the management of intraparotid facial nerve schwannoma and proposed decision-making algorithm. Eur Arch Otorhinolaryngol. 266(4):475-9, 2009
                                                                                  17. Guzzo M et al: Schwannoma in the parotid gland. Experience at our institute and review of the literature. Tumori. 95(6):846-51, 2009
                                                                                  18. Tanna N et al: Intraparotid facial nerve schwannoma: clinician beware. Ear Nose Throat J. 88(8):E18-20, 2009
                                                                                  19. Mehta RP et al: Intraoperative diagnosis of facial nerve schwannoma at parotidectomy. Am J Otolaryngol. 29(2):126-9, 2008
                                                                                  20. Salemis NS et al: Large intraparotid facial nerve schwannoma: case report and review of the literature. Int J Oral Maxillofac Surg. 37(7):679-81, 2008
                                                                                  21. Marchioni D et al: Intraparotid facial nerve schwannoma: literature review and classification proposal. J Laryngol Otol. 121(8):707-12, 2007
                                                                                  22. Ciko Z: [Current treatment of acute leukemias.] Vojnosanit Pregl. 26(11):563-6, 1969