Persistent postnatal patency of normal prenatal connection from pulmonary artery (PA) to proximal descending aorta
Category: Acyanotic, ↑ pulmonary blood flow
Hemodynamics: Left-to-right shunt between aorta & PA
PDA is frequently essential part of complex congenital heart disease
Typical ductal-dependent lesions, including hypoplastic left heart syndrome, severe hypoplastic-type coarctation, & interruption of aortic arch: Conduit for systemic perfusion (right-to-left flow)
D-transposition of great arteries: Necessary for admixture between systemic & pulmonary circuits (left-to-right flow)
Pulmonary atresia & other severe cyanotic heart diseases with right-sided obstruction: Conduit for pulmonary perfusion (left-to-right flow)
PDA is part of persistent fetal circulation syndrome: Right-to-left flow
Severe lung disease (meconium aspiration, surfactant deficiency disease, neonatal pneumonia)
Primary pulmonary hypertension of neonate
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Echocardiographic Findings
Angiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Porayette P et al: Rare association of absent pulmonary valve with intact ventricular septum and patent ductus arteriosus: assessment in a newborn with CT angiography. J Cardiovasc Comput Tomogr. 15(1):e1-2, 2021
Burkett DA: Common left-to-right shunts. Pediatr Clin North Am. 67(5):821-42, 2020
Jadhav SP et al: Correlation of ductus arteriosus length and morphology between computed tomographic angiography and catheter angiography and their relation to ductal stent length. Pediatr Radiol. 50(6):800-9, 2020
Krupiński M et al: Detailed radiological study of the patent ductus arteriosus: a computed tomography study in the Polish population. Folia Morphol (Warsz). 79(3):462-8, 2020
Rajesh V et al: Echocardiography in adult patients with PDA: a simplified approach. Echocardiography. 37(12):2194-8, 2020
Hagadorn JI et al: Covariation of neonatal intensive care unit-level patent ductus arteriosus management and in-neonatal intensive care unit outcomes following preterm birth. J Pediatr. 203:225-33.e1, 2018
Shafi NA et al: Sizing of patent ductus arteriosus in adults for transcatheter closure using the balloon pull-through technique. Catheter Cardiovasc Interv. 91(6):1159-63, 2018
Xu E et al: Ductus arteriosus aneurysm: case report and review of the literature. Arch Pediatr. 25(4):283-5, 2018
El-Khuffash A et al: A patent ductus arteriosus severity score predicts chronic lung disease or death before discharge. J Pediatr. 167(6):1354-61.e2, 2015
Ryan JJ et al: Eisenmenger syndrome with unrepaired patent ductus arteriosus. Circulation. 131(16):e409-11, 2015
Broadhouse KM et al: Assessment of PDA shunt and systemic blood flow in newborns using cardiac MRI. NMR Biomed. 26(9):1135-41, 2013
Brunetti MA et al: Percutaneous closure of patent ductus arteriosus: a multiinstitutional registry comparing multiple devices. Catheter Cardiovasc Interv. 76(5):696-702, 2010
Thai WE et al: Dynamic volume 320-slice CT in the assessment of patent ductus arteriosus for percutaneous closure. Heart. 96(4):321, 2010
Debl K et al: Quantification of left-to-right shunting in adult congenital heart disease: phase-contrast cine MRI compared with invasive oximetry. Br J Radiol. 82(977):386-91, 2009
Schneider DJ et al: Patent ductus arteriosus. Circulation. 114(17):1873-82, 2006
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
Patent ductus arteriosus (PDA)
Synonyms
Persistent arterial duct, patent ductus Botalli
Definitions
Persistent postnatal patency of normal prenatal connection from pulmonary artery (PA) to proximal descending aorta
Category: Acyanotic, ↑ pulmonary blood flow
Hemodynamics: Left-to-right shunt between aorta & PA
PDA is frequently essential part of complex congenital heart disease
Typical ductal-dependent lesions, including hypoplastic left heart syndrome, severe hypoplastic-type coarctation, & interruption of aortic arch: Conduit for systemic perfusion (right-to-left flow)
D-transposition of great arteries: Necessary for admixture between systemic & pulmonary circuits (left-to-right flow)
Pulmonary atresia & other severe cyanotic heart diseases with right-sided obstruction: Conduit for pulmonary perfusion (left-to-right flow)
PDA is part of persistent fetal circulation syndrome: Right-to-left flow
Severe lung disease (meconium aspiration, surfactant deficiency disease, neonatal pneumonia)
Primary pulmonary hypertension of neonate
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Echocardiographic Findings
Angiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Porayette P et al: Rare association of absent pulmonary valve with intact ventricular septum and patent ductus arteriosus: assessment in a newborn with CT angiography. J Cardiovasc Comput Tomogr. 15(1):e1-2, 2021
Burkett DA: Common left-to-right shunts. Pediatr Clin North Am. 67(5):821-42, 2020
Jadhav SP et al: Correlation of ductus arteriosus length and morphology between computed tomographic angiography and catheter angiography and their relation to ductal stent length. Pediatr Radiol. 50(6):800-9, 2020
Krupiński M et al: Detailed radiological study of the patent ductus arteriosus: a computed tomography study in the Polish population. Folia Morphol (Warsz). 79(3):462-8, 2020
Rajesh V et al: Echocardiography in adult patients with PDA: a simplified approach. Echocardiography. 37(12):2194-8, 2020
Hagadorn JI et al: Covariation of neonatal intensive care unit-level patent ductus arteriosus management and in-neonatal intensive care unit outcomes following preterm birth. J Pediatr. 203:225-33.e1, 2018
Shafi NA et al: Sizing of patent ductus arteriosus in adults for transcatheter closure using the balloon pull-through technique. Catheter Cardiovasc Interv. 91(6):1159-63, 2018
Xu E et al: Ductus arteriosus aneurysm: case report and review of the literature. Arch Pediatr. 25(4):283-5, 2018
El-Khuffash A et al: A patent ductus arteriosus severity score predicts chronic lung disease or death before discharge. J Pediatr. 167(6):1354-61.e2, 2015
Ryan JJ et al: Eisenmenger syndrome with unrepaired patent ductus arteriosus. Circulation. 131(16):e409-11, 2015
Broadhouse KM et al: Assessment of PDA shunt and systemic blood flow in newborns using cardiac MRI. NMR Biomed. 26(9):1135-41, 2013
Brunetti MA et al: Percutaneous closure of patent ductus arteriosus: a multiinstitutional registry comparing multiple devices. Catheter Cardiovasc Interv. 76(5):696-702, 2010
Thai WE et al: Dynamic volume 320-slice CT in the assessment of patent ductus arteriosus for percutaneous closure. Heart. 96(4):321, 2010
Debl K et al: Quantification of left-to-right shunting in adult congenital heart disease: phase-contrast cine MRI compared with invasive oximetry. Br J Radiol. 82(977):386-91, 2009
Schneider DJ et al: Patent ductus arteriosus. Circulation. 114(17):1873-82, 2006
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