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KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Patent ductus arteriosus (PDA)
Synonyms
- Persistent arterial duct, patent ductus Botalli
Definitions
- Persistent postnatal patency of normal prenatal connection from pulmonary artery (PA) to proximal descending aorta
- Category: Acyanotic, ↑ pulmonary blood flow
- Hemodynamics: Left-to-right shunt between aorta & PA
- PDA is frequently essential part of complex congenital heart disease
- Typical ductal-dependent lesions, including hypoplastic left heart syndrome, severe hypoplastic-type coarctation, & interruption of aortic arch: Conduit for systemic perfusion (right-to-left flow)
- D-transposition of great arteries: Necessary for admixture between systemic & pulmonary circuits (left-to-right flow)
- Pulmonary atresia & other severe cyanotic heart diseases with right-sided obstruction: Conduit for pulmonary perfusion (left-to-right flow)
- PDA is part of persistent fetal circulation syndrome: Right-to-left flow
- Severe lung disease (meconium aspiration, surfactant deficiency disease, neonatal pneumonia)
- Primary pulmonary hypertension of neonate
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Echocardiographic Findings
Angiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
- Porayette P et al: Rare association of absent pulmonary valve with intact ventricular septum and patent ductus arteriosus: assessment in a newborn with CT angiography. J Cardiovasc Comput Tomogr. 15(1):e1-2, 2021
- Burkett DA: Common left-to-right shunts. Pediatr Clin North Am. 67(5):821-42, 2020
- Jadhav SP et al: Correlation of ductus arteriosus length and morphology between computed tomographic angiography and catheter angiography and their relation to ductal stent length. Pediatr Radiol. 50(6):800-9, 2020
- Krupiński M et al: Detailed radiological study of the patent ductus arteriosus: a computed tomography study in the Polish population. Folia Morphol (Warsz). 79(3):462-8, 2020
- Rajesh V et al: Echocardiography in adult patients with PDA: a simplified approach. Echocardiography. 37(12):2194-8, 2020
- Hagadorn JI et al: Covariation of neonatal intensive care unit-level patent ductus arteriosus management and in-neonatal intensive care unit outcomes following preterm birth. J Pediatr. 203:225-33.e1, 2018
- Shafi NA et al: Sizing of patent ductus arteriosus in adults for transcatheter closure using the balloon pull-through technique. Catheter Cardiovasc Interv. 91(6):1159-63, 2018
- Xu E et al: Ductus arteriosus aneurysm: case report and review of the literature. Arch Pediatr. 25(4):283-5, 2018
- El-Khuffash A et al: A patent ductus arteriosus severity score predicts chronic lung disease or death before discharge. J Pediatr. 167(6):1354-61.e2, 2015
- Ryan JJ et al: Eisenmenger syndrome with unrepaired patent ductus arteriosus. Circulation. 131(16):e409-11, 2015
- Anilkumar M: Patent ductus arteriosus. Cardiol Clin. 31(3):417-30, 2013
- Broadhouse KM et al: Assessment of PDA shunt and systemic blood flow in newborns using cardiac MRI. NMR Biomed. 26(9):1135-41, 2013
- Brunetti MA et al: Percutaneous closure of patent ductus arteriosus: a multiinstitutional registry comparing multiple devices. Catheter Cardiovasc Interv. 76(5):696-702, 2010
- Thai WE et al: Dynamic volume 320-slice CT in the assessment of patent ductus arteriosus for percutaneous closure. Heart. 96(4):321, 2010
- Debl K et al: Quantification of left-to-right shunting in adult congenital heart disease: phase-contrast cine MRI compared with invasive oximetry. Br J Radiol. 82(977):386-91, 2009
- Schneider DJ et al: Patent ductus arteriosus. Circulation. 114(17):1873-82, 2006
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Patent ductus arteriosus (PDA)
Synonyms
- Persistent arterial duct, patent ductus Botalli
Definitions
- Persistent postnatal patency of normal prenatal connection from pulmonary artery (PA) to proximal descending aorta
- Category: Acyanotic, ↑ pulmonary blood flow
- Hemodynamics: Left-to-right shunt between aorta & PA
- PDA is frequently essential part of complex congenital heart disease
- Typical ductal-dependent lesions, including hypoplastic left heart syndrome, severe hypoplastic-type coarctation, & interruption of aortic arch: Conduit for systemic perfusion (right-to-left flow)
- D-transposition of great arteries: Necessary for admixture between systemic & pulmonary circuits (left-to-right flow)
- Pulmonary atresia & other severe cyanotic heart diseases with right-sided obstruction: Conduit for pulmonary perfusion (left-to-right flow)
- PDA is part of persistent fetal circulation syndrome: Right-to-left flow
- Severe lung disease (meconium aspiration, surfactant deficiency disease, neonatal pneumonia)
- Primary pulmonary hypertension of neonate
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Echocardiographic Findings
Angiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
- Porayette P et al: Rare association of absent pulmonary valve with intact ventricular septum and patent ductus arteriosus: assessment in a newborn with CT angiography. J Cardiovasc Comput Tomogr. 15(1):e1-2, 2021
- Burkett DA: Common left-to-right shunts. Pediatr Clin North Am. 67(5):821-42, 2020
- Jadhav SP et al: Correlation of ductus arteriosus length and morphology between computed tomographic angiography and catheter angiography and their relation to ductal stent length. Pediatr Radiol. 50(6):800-9, 2020
- Krupiński M et al: Detailed radiological study of the patent ductus arteriosus: a computed tomography study in the Polish population. Folia Morphol (Warsz). 79(3):462-8, 2020
- Rajesh V et al: Echocardiography in adult patients with PDA: a simplified approach. Echocardiography. 37(12):2194-8, 2020
- Hagadorn JI et al: Covariation of neonatal intensive care unit-level patent ductus arteriosus management and in-neonatal intensive care unit outcomes following preterm birth. J Pediatr. 203:225-33.e1, 2018
- Shafi NA et al: Sizing of patent ductus arteriosus in adults for transcatheter closure using the balloon pull-through technique. Catheter Cardiovasc Interv. 91(6):1159-63, 2018
- Xu E et al: Ductus arteriosus aneurysm: case report and review of the literature. Arch Pediatr. 25(4):283-5, 2018
- El-Khuffash A et al: A patent ductus arteriosus severity score predicts chronic lung disease or death before discharge. J Pediatr. 167(6):1354-61.e2, 2015
- Ryan JJ et al: Eisenmenger syndrome with unrepaired patent ductus arteriosus. Circulation. 131(16):e409-11, 2015
- Anilkumar M: Patent ductus arteriosus. Cardiol Clin. 31(3):417-30, 2013
- Broadhouse KM et al: Assessment of PDA shunt and systemic blood flow in newborns using cardiac MRI. NMR Biomed. 26(9):1135-41, 2013
- Brunetti MA et al: Percutaneous closure of patent ductus arteriosus: a multiinstitutional registry comparing multiple devices. Catheter Cardiovasc Interv. 76(5):696-702, 2010
- Thai WE et al: Dynamic volume 320-slice CT in the assessment of patent ductus arteriosus for percutaneous closure. Heart. 96(4):321, 2010
- Debl K et al: Quantification of left-to-right shunting in adult congenital heart disease: phase-contrast cine MRI compared with invasive oximetry. Br J Radiol. 82(977):386-91, 2009
- Schneider DJ et al: Patent ductus arteriosus. Circulation. 114(17):1873-82, 2006
