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Periosteal Chondrosarcoma
Behrang Amini, MD, PhD; B. J. Manaster, MD, PhD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Synonyms

              • Not recommended: juxtacortical chondrosarcoma
            • Definitions

              • Chondrosarcoma arising in periosteal layer of tubular bones

            IMAGING

            • General Features

              • Radiographic Findings

                • MR Findings

                  • Nuclear Medicine Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • Gross Pathologic & Surgical Features

                        • Microscopic Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Consider

                                    Selected References

                                    1. Cleven AHG et al: Periosteal chondrosarcoma. In Fletcher CDM et al: WHO Classification of Tumours: Tumours of Soft Tissue and Bone. IARC Press. 381-2, 2020
                                    2. Pacheco M et al: Primary malignant tumors of bone surface: a review with emphasis in differential diagnosis. J Cancer Metastasis Treat. 6:49, 2020. http://dx.doi.org/10.20517/2394-4722.2020.85
                                    3. Cleven AH et al: Periosteal chondrosarcoma: a histopathological and molecular analysis of a rare chondrosarcoma subtype. Histopathology. 67(4):483-90, 2015
                                    4. Liu X et al: Bony metastases following complete resection of periosteal chondrosarcoma. World J Surg Oncol. 13:121, 2015
                                    5. Goedhart LM et al: The presentation, treatment and outcome of periosteal chondrosarcoma in the Netherlands. Bone Joint J. 96-B(6):823-8, 2014
                                    6. Morimoto S et al: Usefulness of PET/CT for diagnosis of periosteal chondrosarcoma of the femur: a case report. Oncol Lett. 7(6):1826-8, 2014
                                    7. Chaabane S et al: Periosteal chondrosarcoma. AJR Am J Roentgenol. 192(1):W1-6, 2009
                                    8. Robinson P et al: Periosteal chondroid tumors: radiologic evaluation with pathologic correlation. AJR Am J Roentgenol. 177(5):1183-8, 2001
                                    9. Vanel D et al: Radiological features of 24 periosteal chondrosarcomas. Skeletal Radiol. 30(4):208-12, 2001
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Pathology

                                            • Clinical Issues

                                              TERMINOLOGY

                                              • Synonyms

                                                • Not recommended: juxtacortical chondrosarcoma
                                              • Definitions

                                                • Chondrosarcoma arising in periosteal layer of tubular bones

                                              IMAGING

                                              • General Features

                                                • Radiographic Findings

                                                  • MR Findings

                                                    • Nuclear Medicine Findings

                                                      DIFFERENTIAL DIAGNOSIS

                                                        PATHOLOGY

                                                        • Gross Pathologic & Surgical Features

                                                          • Microscopic Features

                                                            CLINICAL ISSUES

                                                            • Presentation

                                                              • Demographics

                                                                • Natural History & Prognosis

                                                                  • Treatment

                                                                    DIAGNOSTIC CHECKLIST

                                                                    • Consider

                                                                      Selected References

                                                                      1. Cleven AHG et al: Periosteal chondrosarcoma. In Fletcher CDM et al: WHO Classification of Tumours: Tumours of Soft Tissue and Bone. IARC Press. 381-2, 2020
                                                                      2. Pacheco M et al: Primary malignant tumors of bone surface: a review with emphasis in differential diagnosis. J Cancer Metastasis Treat. 6:49, 2020. http://dx.doi.org/10.20517/2394-4722.2020.85
                                                                      3. Cleven AH et al: Periosteal chondrosarcoma: a histopathological and molecular analysis of a rare chondrosarcoma subtype. Histopathology. 67(4):483-90, 2015
                                                                      4. Liu X et al: Bony metastases following complete resection of periosteal chondrosarcoma. World J Surg Oncol. 13:121, 2015
                                                                      5. Goedhart LM et al: The presentation, treatment and outcome of periosteal chondrosarcoma in the Netherlands. Bone Joint J. 96-B(6):823-8, 2014
                                                                      6. Morimoto S et al: Usefulness of PET/CT for diagnosis of periosteal chondrosarcoma of the femur: a case report. Oncol Lett. 7(6):1826-8, 2014
                                                                      7. Chaabane S et al: Periosteal chondrosarcoma. AJR Am J Roentgenol. 192(1):W1-6, 2009
                                                                      8. Robinson P et al: Periosteal chondroid tumors: radiologic evaluation with pathologic correlation. AJR Am J Roentgenol. 177(5):1183-8, 2001
                                                                      9. Vanel D et al: Radiological features of 24 periosteal chondrosarcomas. Skeletal Radiol. 30(4):208-12, 2001