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Periosteal Osteosarcoma
B.J. Manaster, MD, PhD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Clinical Issues

        TERMINOLOGY

        • Abbreviations

          • Osteosarcoma (OS)
        • Synonyms

          • Juxtacortical chondroblastic OS
        • Definitions

          • Intermediate-grade surface OS, usually chondroblastic; ± marrow involvement

        IMAGING

        • General Features

          • Imaging Recommendations

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      • Staging, Grading, & Classification

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      • Image Interpretation Pearls

                                        Selected References

                                        1. Gulia A et al: Oncological and functional outcome of periosteal osteosarcoma. Indian J Orthop. 48(3):279-84, 2014
                                        2. Maheshwari AV et al: Bilateral synchronous tibial periosteal osteosarcoma with familial incidence. Skeletal Radiol. 41(8):1005-9, 2012
                                        3. Cesari M et al: Periosteal osteosarcoma: a single-institution experience. Cancer. 117(8):1731-5, 2011
                                        4. Yarmish G et al: Imaging characteristics of primary osteosarcoma: nonconventional subtypes. Radiographics. 30(6):1653-72, 2010
                                        5. Rose PS et al: Periosteal osteosarcoma: long-term outcome and risk of late recurrence. Clin Orthop Relat Res. 453:314-7, 2006
                                        6. Grimer RJ et al: Periosteal osteosarcoma--a European review of outcome. Eur J Cancer. 41(18):2806-11, 2005
                                        7. Murphey MD et al: Imaging of periosteal osteosarcoma: radiologic-pathologic comparison. Radiology. 233(1):129-38, 2004
                                        8. Ayala AG et al: Periosteal osteosarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours: Tumours of Soft Tissue and Bone, 282-3. Lyon: IARC Press, 2002
                                        9. Murphey MD et al: The many faces of osteosarcoma. Radiographics. 17(5):1205-31, 1997
                                        10. Wong KT et al: Chondroblastic, grade 3 periosteal osteosarcoma. Skeletal Radiol. 24(1):69-71, 1995
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Clinical Issues

                                              TERMINOLOGY

                                              • Abbreviations

                                                • Osteosarcoma (OS)
                                              • Synonyms

                                                • Juxtacortical chondroblastic OS
                                              • Definitions

                                                • Intermediate-grade surface OS, usually chondroblastic; ± marrow involvement

                                              IMAGING

                                              • General Features

                                                • Imaging Recommendations

                                                  • Radiographic Findings

                                                    • CT Findings

                                                      • MR Findings

                                                        DIFFERENTIAL DIAGNOSIS

                                                          PATHOLOGY

                                                          • General Features

                                                            • Staging, Grading, & Classification

                                                              • Gross Pathologic & Surgical Features

                                                                • Microscopic Features

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Demographics

                                                                      • Natural History & Prognosis

                                                                        • Treatment

                                                                          DIAGNOSTIC CHECKLIST

                                                                          • Consider

                                                                            • Image Interpretation Pearls

                                                                              Selected References

                                                                              1. Gulia A et al: Oncological and functional outcome of periosteal osteosarcoma. Indian J Orthop. 48(3):279-84, 2014
                                                                              2. Maheshwari AV et al: Bilateral synchronous tibial periosteal osteosarcoma with familial incidence. Skeletal Radiol. 41(8):1005-9, 2012
                                                                              3. Cesari M et al: Periosteal osteosarcoma: a single-institution experience. Cancer. 117(8):1731-5, 2011
                                                                              4. Yarmish G et al: Imaging characteristics of primary osteosarcoma: nonconventional subtypes. Radiographics. 30(6):1653-72, 2010
                                                                              5. Rose PS et al: Periosteal osteosarcoma: long-term outcome and risk of late recurrence. Clin Orthop Relat Res. 453:314-7, 2006
                                                                              6. Grimer RJ et al: Periosteal osteosarcoma--a European review of outcome. Eur J Cancer. 41(18):2806-11, 2005
                                                                              7. Murphey MD et al: Imaging of periosteal osteosarcoma: radiologic-pathologic comparison. Radiology. 233(1):129-38, 2004
                                                                              8. Ayala AG et al: Periosteal osteosarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours: Tumours of Soft Tissue and Bone, 282-3. Lyon: IARC Press, 2002
                                                                              9. Murphey MD et al: The many faces of osteosarcoma. Radiographics. 17(5):1205-31, 1997
                                                                              10. Wong KT et al: Chondroblastic, grade 3 periosteal osteosarcoma. Skeletal Radiol. 24(1):69-71, 1995