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Perivascular Space Enhancing Lesions
Karen L. Salzman, MD
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DIFFERENTIAL DIAGNOSIS

    ESSENTIAL INFORMATION

    • Key Differential Diagnosis Issues

      • Helpful Clues for Common Diagnoses

        • Helpful Clues for Less Common Diagnoses

          • Helpful Clues for Rare Diagnoses

            • Alternative Differential Approaches

              Selected References

              1. Becker J et al: Primary central nervous system vasculitis and its mimicking diseases - clinical features, outcome, comorbidities and diagnostic results - A case control study. Clin Neurol Neurosurg. 156:48-54, 2017
              2. Naganawa S et al: Gd-based Contrast Enhancement of the Perivascular Spaces in the Basal Ganglia. Magn Reson Med Sci. 16(1):61-65, 2017
              3. Rapalino O et al: Intracranial Infectious and Inflammatory Diseases Presenting as Neurosurgical Pathologies. Neurosurgery. ePub, 2017
              4. Salvarani C et al: Imaging Findings of Cerebral Amyloid Angiopathy, Aβ-Related Angiitis (ABRA), and Cerebral Amyloid Angiopathy-Related Inflammation: A Single-Institution 25-Year Experience. Medicine (Baltimore). 95(20):e3613, 2016
              5. Zhang YX et al: CLIPPERS with diffuse white matter and longitudinally extensive spinal cord involvement. Neurology. 86(1):103-5, 2016
              6. Moussaddy A et al: Inflammatory Cerebral Amyloid Angiopathy, Amyloid-β-Related Angiitis, and Primary Angiitis of the Central Nervous System: Similarities and Differences. Stroke. 46(9):e210-3, 2015
              7. Saigal G et al: Acute lacunar infarcts in CLIPPERS: is the chronic infiltrative lymphocytic perivascular disease process to blame? Neuroradiol J. 26(6):629-35, 2013
              8. Pittock SJ et al: Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS). Brain. 133(9):2626-34, 2010
              Related Anatomy
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              Related Differential Diagnoses
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              References
              Tables

              Tables

              DIFFERENTIAL DIAGNOSIS

                ESSENTIAL INFORMATION

                • Key Differential Diagnosis Issues

                  • Helpful Clues for Common Diagnoses

                    • Helpful Clues for Less Common Diagnoses

                      • Helpful Clues for Rare Diagnoses

                        • Alternative Differential Approaches

                          Selected References

                          1. Becker J et al: Primary central nervous system vasculitis and its mimicking diseases - clinical features, outcome, comorbidities and diagnostic results - A case control study. Clin Neurol Neurosurg. 156:48-54, 2017
                          2. Naganawa S et al: Gd-based Contrast Enhancement of the Perivascular Spaces in the Basal Ganglia. Magn Reson Med Sci. 16(1):61-65, 2017
                          3. Rapalino O et al: Intracranial Infectious and Inflammatory Diseases Presenting as Neurosurgical Pathologies. Neurosurgery. ePub, 2017
                          4. Salvarani C et al: Imaging Findings of Cerebral Amyloid Angiopathy, Aβ-Related Angiitis (ABRA), and Cerebral Amyloid Angiopathy-Related Inflammation: A Single-Institution 25-Year Experience. Medicine (Baltimore). 95(20):e3613, 2016
                          5. Zhang YX et al: CLIPPERS with diffuse white matter and longitudinally extensive spinal cord involvement. Neurology. 86(1):103-5, 2016
                          6. Moussaddy A et al: Inflammatory Cerebral Amyloid Angiopathy, Amyloid-β-Related Angiitis, and Primary Angiitis of the Central Nervous System: Similarities and Differences. Stroke. 46(9):e210-3, 2015
                          7. Saigal G et al: Acute lacunar infarcts in CLIPPERS: is the chronic infiltrative lymphocytic perivascular disease process to blame? Neuroradiol J. 26(6):629-35, 2013
                          8. Pittock SJ et al: Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS). Brain. 133(9):2626-34, 2010