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PET/CT Artifacts
Todd M. Blodgett, MD; Ashok Muthukrishnan, MD
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KEY FACTS

  • AC Artifacts

    • Respiratory Artifacts

      • Factors That Decrease Image Quality

        • CT Protocols

          ATTENUATION CORRECTION (AC) ARTIFACTS

          • Sources

            • Methods to Avoid Misinterpretation of AC Artifacts

              IMAGING ISSUES

              • Oral and IV Contrast

                • Ports and Other High-Contrast Materials

                  • Metallic Devices

                    • Calcified Lymph Nodes

                      • Non-AC Artifacts: Diaphragmatic Motion

                        • Other Image Quality Considerations

                          IMAGING PROTOCOLS

                          • CT-based Attenuation Correction

                            • CT Portion of PET/CT Examination

                              Selected References

                              1. Hamill JJ et al: Respiratory-gated CT as a tool for the simulation of breathing artifacts in PET and PET/CT. Med Phys. 35(2):576-85, 2008
                              2. Nahmias C et al: Does Reducing CT Artifacts from Dental Implants Influence the PET Interpretation in PET/CT Studies of Oral Cancer and Head and Neck Cancer? J Nucl Med. 49(7):1047-1052, 2008
                              3. Bacharach SL: PET/CT attenuation correction: breathing lessons. J Nucl Med. 48(5):677-9, 2007
                              4. Cook GJ: Pitfalls in PET/CT interpretation. Q J Nucl Med Mol Imaging. 51(3):235-43, 2007
                              5. Kaneta T et al: High-density materials do not always induce artifacts on PET/CT: what is responsible for the difference? Nucl Med Commun. 28(6):495-9, 2007
                              6. Beyer T et al: Whole-body 18F-FDG PET/CT in the presence of truncation artifacts. J Nucl Med. 47(1):91-9, 2006
                              7. Blodgett TM et al: Positron emission tomography/computed tomography: protocol issues and options. Semin Nucl Med. 36(2):157-68, 2006
                              8. Carney JP et al: Method for transforming CT images for attenuation correction in PET/CT imaging. Med Phys. 33(4):976-83, 2006
                              9. Mawlawi O et al: Truncation artifact on PET/CT: impact on measurements of activity concentration and assessment of a correction algorithm. AJR Am J Roentgenol. 186(5):1458-67, 2006
                              10. Mawlawi O et al: PET/CT imaging techniques, considerations, and artifacts. J Thorac Imaging. 21(2):99-110, 2006
                              11. Beyer T et al: Optimized intravenous contrast administration for diagnostic whole-body 18F-FDG PET/CT. J Nucl Med. 46(3):429-35, 2005
                              12. Blodgett TM et al: Issues, controversies, and clinical utility of combined PET/CT imaging: what is the interpreting physician facing? AJR Am J Roentgenol. 184(5 Suppl):S138-45, 2005
                              Related Anatomy
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                              Related Differential Diagnoses
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                              References
                              Tables

                              Tables

                              KEY FACTS

                              • AC Artifacts

                                • Respiratory Artifacts

                                  • Factors That Decrease Image Quality

                                    • CT Protocols

                                      ATTENUATION CORRECTION (AC) ARTIFACTS

                                      • Sources

                                        • Methods to Avoid Misinterpretation of AC Artifacts

                                          IMAGING ISSUES

                                          • Oral and IV Contrast

                                            • Ports and Other High-Contrast Materials

                                              • Metallic Devices

                                                • Calcified Lymph Nodes

                                                  • Non-AC Artifacts: Diaphragmatic Motion

                                                    • Other Image Quality Considerations

                                                      IMAGING PROTOCOLS

                                                      • CT-based Attenuation Correction

                                                        • CT Portion of PET/CT Examination

                                                          Selected References

                                                          1. Hamill JJ et al: Respiratory-gated CT as a tool for the simulation of breathing artifacts in PET and PET/CT. Med Phys. 35(2):576-85, 2008
                                                          2. Nahmias C et al: Does Reducing CT Artifacts from Dental Implants Influence the PET Interpretation in PET/CT Studies of Oral Cancer and Head and Neck Cancer? J Nucl Med. 49(7):1047-1052, 2008
                                                          3. Bacharach SL: PET/CT attenuation correction: breathing lessons. J Nucl Med. 48(5):677-9, 2007
                                                          4. Cook GJ: Pitfalls in PET/CT interpretation. Q J Nucl Med Mol Imaging. 51(3):235-43, 2007
                                                          5. Kaneta T et al: High-density materials do not always induce artifacts on PET/CT: what is responsible for the difference? Nucl Med Commun. 28(6):495-9, 2007
                                                          6. Beyer T et al: Whole-body 18F-FDG PET/CT in the presence of truncation artifacts. J Nucl Med. 47(1):91-9, 2006
                                                          7. Blodgett TM et al: Positron emission tomography/computed tomography: protocol issues and options. Semin Nucl Med. 36(2):157-68, 2006
                                                          8. Carney JP et al: Method for transforming CT images for attenuation correction in PET/CT imaging. Med Phys. 33(4):976-83, 2006
                                                          9. Mawlawi O et al: Truncation artifact on PET/CT: impact on measurements of activity concentration and assessment of a correction algorithm. AJR Am J Roentgenol. 186(5):1458-67, 2006
                                                          10. Mawlawi O et al: PET/CT imaging techniques, considerations, and artifacts. J Thorac Imaging. 21(2):99-110, 2006
                                                          11. Beyer T et al: Optimized intravenous contrast administration for diagnostic whole-body 18F-FDG PET/CT. J Nucl Med. 46(3):429-35, 2005
                                                          12. Blodgett TM et al: Issues, controversies, and clinical utility of combined PET/CT imaging: what is the interpreting physician facing? AJR Am J Roentgenol. 184(5 Suppl):S138-45, 2005