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Pheochromocytoma and Paraganglioma
Akram M. Shaaban, MBBCh
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6

OVERVIEW

  • General Comments

    PATHOLOGY

    • Routes of Spread

      • General Features

        • Gross Pathology & Surgical Features

          IMAGING FINDINGS

          • Surveillance

            • Detection

              • Staging

                CLINICAL ISSUES

                • Presentation

                  • Cancer Natural History & Prognosis

                    • Treatment Options

                      REPORTING CHECKLIST

                      • T Staging

                        • N Staging

                          • M Staging

                            Selected References

                            1. Hescot S et al: Prognosis of malignant pheochromocytoma and paraganglioma (MAPP-Prono study): an ENS@T retrospective study. J Clin Endocrinol Metab. 104(6):2367-74, 2019
                            2. Kroiss AS et al: 68Ga-DOTATOC PET/CT in the localization of metastatic extra-adrenal paraganglioma and pheochromocytoma compared with 18F-DOPA PET/CT. Rev Esp Med Nucl Imagen Mol. 38(2):94-9, 2019
                            3. Amin MB et al: AJCC Cancer Staging Manual. 8th Ed. Springer New York, 2017
                            4. Nockel P et al: Preoperative 18F-FDG PET/CT in pheochromocytomas and paragangliomas allows for precision surgery. Ann Surg. 269(4):741-7, 2018
                            5. Daniel E et al: Rapid-sequence MRI for long-term surveillance for paraganglioma and phaeochromocytoma in patients with succinate dehydrogenase mutations. Eur J Endocrinol. 175(6):561-70, 2016
                            6. Shaaban AM et al: Fat-containing retroperitoneal lesions: imaging characteristics, localization, and differential diagnosis. Radiographics. 36(3):710-34, 2016
                            7. Angelousi A et al: Metastatic pheochromocytoma and paraganglioma. Eur J Clin Invest. 45(9):986-97, 2015
                            8. Timmers HJ et al: Staging and functional characterization of pheochromocytoma and paraganglioma by 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography. J Natl Cancer Inst. 104(9):700-8, 2012
                            9. Vanderveen KA et al: Biopsy of pheochromocytomas and paragangliomas: potential for disaster. Surgery. 146(6):1158-66, 2009
                            10. Bessell-Browne R et al: CT of pheochromocytoma and paraganglioma: risk of adverse events with i.v. administration of nonionic contrast material. AJR Am J Roentgenol. 188(4):970-4, 2007
                            Related Anatomy
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                            Related Differential Diagnoses
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                            References
                            Tables

                            Tables

                            OVERVIEW

                            • General Comments

                              PATHOLOGY

                              • Routes of Spread

                                • General Features

                                  • Gross Pathology & Surgical Features

                                    IMAGING FINDINGS

                                    • Surveillance

                                      • Detection

                                        • Staging

                                          CLINICAL ISSUES

                                          • Presentation

                                            • Cancer Natural History & Prognosis

                                              • Treatment Options

                                                REPORTING CHECKLIST

                                                • T Staging

                                                  • N Staging

                                                    • M Staging

                                                      Selected References

                                                      1. Hescot S et al: Prognosis of malignant pheochromocytoma and paraganglioma (MAPP-Prono study): an ENS@T retrospective study. J Clin Endocrinol Metab. 104(6):2367-74, 2019
                                                      2. Kroiss AS et al: 68Ga-DOTATOC PET/CT in the localization of metastatic extra-adrenal paraganglioma and pheochromocytoma compared with 18F-DOPA PET/CT. Rev Esp Med Nucl Imagen Mol. 38(2):94-9, 2019
                                                      3. Amin MB et al: AJCC Cancer Staging Manual. 8th Ed. Springer New York, 2017
                                                      4. Nockel P et al: Preoperative 18F-FDG PET/CT in pheochromocytomas and paragangliomas allows for precision surgery. Ann Surg. 269(4):741-7, 2018
                                                      5. Daniel E et al: Rapid-sequence MRI for long-term surveillance for paraganglioma and phaeochromocytoma in patients with succinate dehydrogenase mutations. Eur J Endocrinol. 175(6):561-70, 2016
                                                      6. Shaaban AM et al: Fat-containing retroperitoneal lesions: imaging characteristics, localization, and differential diagnosis. Radiographics. 36(3):710-34, 2016
                                                      7. Angelousi A et al: Metastatic pheochromocytoma and paraganglioma. Eur J Clin Invest. 45(9):986-97, 2015
                                                      8. Timmers HJ et al: Staging and functional characterization of pheochromocytoma and paraganglioma by 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography. J Natl Cancer Inst. 104(9):700-8, 2012
                                                      9. Vanderveen KA et al: Biopsy of pheochromocytomas and paragangliomas: potential for disaster. Surgery. 146(6):1158-66, 2009
                                                      10. Bessell-Browne R et al: CT of pheochromocytoma and paraganglioma: risk of adverse events with i.v. administration of nonionic contrast material. AJR Am J Roentgenol. 188(4):970-4, 2007