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Pineal Cyst
Anne G. Osborn, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Pineal cyst (PC)
            • Synonyms

              • Glial cyst of pineal gland
            • Definitions

              • Nonneoplastic intrapineal glial-lined cyst

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Angiographic Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Lukewich MK et al: Spontaneous resolution of dorsal midbrain syndrome caused by a pineal cyst. World Neurosurg. 136:289-92, 2020
                                          2. Pitskhelauri DI et al: Pineal cyst-related aqueductal stenosis as cause of intractable headaches in nonhydrocephalic patients. World Neurosurg. 123:e147-e55, 2019
                                          3. Bezuidenhout AF et al: Relationship between pineal cyst size and aqueductal CSF flow measured by phase contrast MRI. J Neurosurg Sci. ePub, 2018
                                          4. Gokce E et al: Evaluation of pineal cysts with magnetic resonance imaging. World J Radiol. 10(7):65-77, 2018
                                          5. Evans RW: Incidental findings and normal anatomical variants on MRI of the brain in adults for primary headaches. Headache. 57(5):780-91, 2017
                                          6. Májovský M et al: Conservative and surgical treatment of patients with pineal cysts: A prospective case series of 110 patients. World Neurosurg. ePub, 2017
                                          7. Ramji S et al: Normal neuroanatomical variants that may be misinterpreted as disease entities. Clin Radiol. 72(10):810-25, 2017
                                          8. Starke RM et al: Pineal cysts and other pineal region malignancies: determining factors predictive of hydrocephalus and malignancy. J Neurosurg. 1-6, 2016
                                          9. Kalani MY et al: Pineal cyst resection in the absence of ventriculomegaly or Parinaud's syndrome: clinical outcomes and implications for patient selection. J Neurosurg. 1-5, 2015
                                          10. Fakhran S et al: Pineocytoma mimicking a pineal cyst on imaging: true diagnostic dilemma or a case of incomplete imaging? AJNR Am J Neuroradiol. 29(1):159-63, 2008
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Abbreviations

                                                      • Pineal cyst (PC)
                                                    • Synonyms

                                                      • Glial cyst of pineal gland
                                                    • Definitions

                                                      • Nonneoplastic intrapineal glial-lined cyst

                                                    IMAGING

                                                    • General Features

                                                      • CT Findings

                                                        • MR Findings

                                                          • Angiographic Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Lukewich MK et al: Spontaneous resolution of dorsal midbrain syndrome caused by a pineal cyst. World Neurosurg. 136:289-92, 2020
                                                                                  2. Pitskhelauri DI et al: Pineal cyst-related aqueductal stenosis as cause of intractable headaches in nonhydrocephalic patients. World Neurosurg. 123:e147-e55, 2019
                                                                                  3. Bezuidenhout AF et al: Relationship between pineal cyst size and aqueductal CSF flow measured by phase contrast MRI. J Neurosurg Sci. ePub, 2018
                                                                                  4. Gokce E et al: Evaluation of pineal cysts with magnetic resonance imaging. World J Radiol. 10(7):65-77, 2018
                                                                                  5. Evans RW: Incidental findings and normal anatomical variants on MRI of the brain in adults for primary headaches. Headache. 57(5):780-91, 2017
                                                                                  6. Májovský M et al: Conservative and surgical treatment of patients with pineal cysts: A prospective case series of 110 patients. World Neurosurg. ePub, 2017
                                                                                  7. Ramji S et al: Normal neuroanatomical variants that may be misinterpreted as disease entities. Clin Radiol. 72(10):810-25, 2017
                                                                                  8. Starke RM et al: Pineal cysts and other pineal region malignancies: determining factors predictive of hydrocephalus and malignancy. J Neurosurg. 1-6, 2016
                                                                                  9. Kalani MY et al: Pineal cyst resection in the absence of ventriculomegaly or Parinaud's syndrome: clinical outcomes and implications for patient selection. J Neurosurg. 1-5, 2015
                                                                                  10. Fakhran S et al: Pineocytoma mimicking a pineal cyst on imaging: true diagnostic dilemma or a case of incomplete imaging? AJNR Am J Neuroradiol. 29(1):159-63, 2008