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Pituicytoma
Karen L. Salzman, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Synonyms

                • Less preferred terms include infundibuloma and posterior pituitary astrocytoma
              • Definitions

                • Rare tumor arising from pituicytes, specialized glial cells in neurohypophysis and infundibulum

              IMAGING

              • General Features

                • CT Findings

                  • MR Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Staging, Grading, & Classification

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          Selected References

                                          1. Zygourakis CC et al: Pituicytomas and spindle cell oncocytomas: modern case series from the University of California, San Francisco. Pituitary. 18(1):150-8, 2015
                                          2. Feng M et al: Surgical management of pituicytomas: case series and comprehensive literature review. Pituitary. 17(5):399-413, 2014
                                          3. Teti C et al: Pituitary image: pituicytoma. Pituitary. ePub, 2014
                                          4. Kleinschmidt-DeMasters BK et al: Update on hypophysitis and TTF-1 expressing sellar region masses. Brain Pathol. 23(5):495-514, 2013
                                          5. Secci F et al: Pituicytomas: radiological findings, clinical behavior and surgical management. Acta Neurochir (Wien). 154(4):649-57; discussion 657, 2012
                                          6. Covington MF et al: Pituicytoma, spindle cell oncocytoma, and granular cell tumor: clarification and meta-analysis of the world literature since 1893. AJNR Am J Neuroradiol. 32(11):2067-72, 2011
                                          7. Brat DJ et al: Newly codified glial neoplasms of the 2007 WHO Classification of Tumours of the Central Nervous System: angiocentric glioma, pilomyxoid astrocytoma and pituicytoma. Brain Pathol. 17(3):319-24, 2007
                                          8. Louis DN et al: The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007 Aug;114(2):97-109. Epub 2007 Jul 6. Review. Erratum in: Acta Neuropathol. 114(5):547, 2007
                                          9. Wesseling et al: Pituicytoma. In Louis DN et al (eds): WHO Classification of Tumours of the Central Nervous System. Lyon, France: IARC Press. 243-4, 2007
                                          10. Benveniste RJ et al: Pituicytoma presenting with spontaneous hemorrhage. Pituitary. 9(1):53-8, 2006
                                          11. Gibbs WN et al: Pituicytoma: diagnostic features on selective carotid angiography and MR imaging. AJNR Am J Neuroradiol. 27(8):1639-42, 2006
                                          12. Takei H et al: Pituicytoma incidentally found at autopsy. Pathol Int. 55(11):745-9, 2005
                                          13. Ulm AJ et al: Pituicytoma: report of two cases and clues regarding histogenesis. Neurosurgery. 2004 Mar;54(3):753-7; discussion 757-8. Erratum in: Neurosurgery. 54(5):1252, 2004
                                          14. Katsuta T et al: Distinctions between pituicytoma and ordinary pilocytic astrocytoma. Case report. J Neurosurg. 98(2):404-6, 2003
                                          15. Figarella-Branger D et al: Pituicytomas, a mis-diagnosed benign tumor of the neurohypophysis: report of three cases. Acta Neuropathol. 104(3):313-9, 2002
                                          16. Brat DJ et al: Pituicytoma: a distinctive low-grade glioma of the neurohypophysis. Am J Surg Pathol. 24(3):362-8, 2000
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Synonyms

                                                        • Less preferred terms include infundibuloma and posterior pituitary astrocytoma
                                                      • Definitions

                                                        • Rare tumor arising from pituicytes, specialized glial cells in neurohypophysis and infundibulum

                                                      IMAGING

                                                      • General Features

                                                        • CT Findings

                                                          • MR Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Staging, Grading, & Classification

                                                                    • Gross Pathologic & Surgical Features

                                                                      • Microscopic Features

                                                                        CLINICAL ISSUES

                                                                        • Presentation

                                                                          • Demographics

                                                                            • Natural History & Prognosis

                                                                              • Treatment

                                                                                DIAGNOSTIC CHECKLIST

                                                                                • Consider

                                                                                  Selected References

                                                                                  1. Zygourakis CC et al: Pituicytomas and spindle cell oncocytomas: modern case series from the University of California, San Francisco. Pituitary. 18(1):150-8, 2015
                                                                                  2. Feng M et al: Surgical management of pituicytomas: case series and comprehensive literature review. Pituitary. 17(5):399-413, 2014
                                                                                  3. Teti C et al: Pituitary image: pituicytoma. Pituitary. ePub, 2014
                                                                                  4. Kleinschmidt-DeMasters BK et al: Update on hypophysitis and TTF-1 expressing sellar region masses. Brain Pathol. 23(5):495-514, 2013
                                                                                  5. Secci F et al: Pituicytomas: radiological findings, clinical behavior and surgical management. Acta Neurochir (Wien). 154(4):649-57; discussion 657, 2012
                                                                                  6. Covington MF et al: Pituicytoma, spindle cell oncocytoma, and granular cell tumor: clarification and meta-analysis of the world literature since 1893. AJNR Am J Neuroradiol. 32(11):2067-72, 2011
                                                                                  7. Brat DJ et al: Newly codified glial neoplasms of the 2007 WHO Classification of Tumours of the Central Nervous System: angiocentric glioma, pilomyxoid astrocytoma and pituicytoma. Brain Pathol. 17(3):319-24, 2007
                                                                                  8. Louis DN et al: The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007 Aug;114(2):97-109. Epub 2007 Jul 6. Review. Erratum in: Acta Neuropathol. 114(5):547, 2007
                                                                                  9. Wesseling et al: Pituicytoma. In Louis DN et al (eds): WHO Classification of Tumours of the Central Nervous System. Lyon, France: IARC Press. 243-4, 2007
                                                                                  10. Benveniste RJ et al: Pituicytoma presenting with spontaneous hemorrhage. Pituitary. 9(1):53-8, 2006
                                                                                  11. Gibbs WN et al: Pituicytoma: diagnostic features on selective carotid angiography and MR imaging. AJNR Am J Neuroradiol. 27(8):1639-42, 2006
                                                                                  12. Takei H et al: Pituicytoma incidentally found at autopsy. Pathol Int. 55(11):745-9, 2005
                                                                                  13. Ulm AJ et al: Pituicytoma: report of two cases and clues regarding histogenesis. Neurosurgery. 2004 Mar;54(3):753-7; discussion 757-8. Erratum in: Neurosurgery. 54(5):1252, 2004
                                                                                  14. Katsuta T et al: Distinctions between pituicytoma and ordinary pilocytic astrocytoma. Case report. J Neurosurg. 98(2):404-6, 2003
                                                                                  15. Figarella-Branger D et al: Pituicytomas, a mis-diagnosed benign tumor of the neurohypophysis: report of three cases. Acta Neuropathol. 104(3):313-9, 2002
                                                                                  16. Brat DJ et al: Pituicytoma: a distinctive low-grade glioma of the neurohypophysis. Am J Surg Pathol. 24(3):362-8, 2000